Concord Pharmaceuticals Ltd.
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Consuming alcohol with Holicef IM does not cause any harmful side effects.
SAFE IF PRESCRIBED
Holicef IM is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
Holicef IM should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is... View More
Holicef IM may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
SAFE IF PRESCRIBED
Holicef IM is safe to use in patients with kidney disease. No dose adjustment of Holicef IM is recommended. However, inform your doctor if you have any ... View More
Holicef IM should be used with caution in patients with severe liver disease. Dose adjustment of Holicef IM may be needed. Please consult your doctor. D... View More
Holicef IM is an antibiotic belonging to the cephalosporin group, which is used to treat bacterial infections in your body. It is effective in infection... View More
Uses of Holicef IM
- Bacterial infections
Side effects of Holicef IM
- Abnormal liver function tests
How to use Holicef IM
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Holicef IM works
Holicef IM is an antibiotic. It kills the bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for the... View More
What if you forget to take Holicef IM?
If you miss a dose of Holicef IM, please consult your doctor.
- Your doctor has prescribed Holicef IM to cure your infection and improve your symptoms.
- Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection harder to treat.
- Discontinue Holicef IM and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your st... View More
Pneumonia, Meningitis, Acute otitis media, Lyme disease, Typhoid fever, Otitis media, Pelvic inflammatory disease, Septicemia, Skin and Skin-Structure I... View More
IV/IM Administration IV: Infuse intermittently over 30 minutes IM: Inject deep into large muscle mass
Susceptible infections IV/IM 1-2 g/day, up to 4 g/day for severe infections. Intra-abdominal Infections Complicated, mild-to-moderate, community ac... View More
Children: IV, IM: 50–75 mg/kg/day, max 2 g/day q24h 50 mg/kg, max 1 g, 1–3 doses IM for AOM q24h 100 mg/kg/day for meningitis, max 4 g/day q12h
Renal impairment: CrCl (ml/min) <10 Max: 2 g daily.
Hypersensitivity to cephalosporins; hyperbilirubinaemic neonates. Do not use calcium or calcium-containing solutions or products with or within 48 hr of... View More
Mode of Action
Ceftriaxone binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in ... View More
History of penicillin allergy; severe renal impairment; pregnancy and lactation; superinfection. Lactation: Drug enters breast milk in low concentrat... View More
>10% Induration after IM injection (5-17%) 1-10% Eosinophilia (6%),Thrombocytosis (5%),Diarrhea (3%),Elevated hepatic transaminases (3%),Leukopenia... View More
Pregnancy Category Note
Pregnancy category: B Lactation: Drug enters breast milk in low concentrations; use with caution
May increase nephrotoxicity of aminoglycosides. May diminish therapeutic effect of BCG, typhoid vaccine, Na picosulfate. May increase anticoagulant effe... View More
Alternative brand for Holicef IM
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More