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I-Penam250mg/vial

Injection
rx_reqRequire Prescription
Incepta Pharmaceuticals Ltd.
Generic: Meropenem
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descriptionSafety Advices
AlcoholAlcohol
SAFE
Consuming alcohol with I-Penam does not cause any harmful side effects.
PregnancyPregnancy
SAFE IF PRESCRIBED
I-Penam is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there... View More
BreastfeedingBreastfeeding
SAFE IF PRESCRIBED
I-Penam is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
DrivingDriving
CONSULT YOUR DOCTOR
It is not known whether I-Penam alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and rea... View More
KidneyKidney
CAUTION
I-Penam should be used with caution in patients with kidney disease. Dose adjustment of I-Penam may be needed. Please consult your doctor.
LiverLiver
SAFE IF PRESCRIBED
I-Penam is safe to use in patients with liver disease. No dose adjustment of I-Penam is recommended.
descriptionMedical Overview

Introduction

I-Penam is an antibiotic that fights bacteria. It is used to treat severe infections of the skin, lungs, stomach, urinary tract, blood and brain (eg. me... View More

Uses of I-Penam

  • Severe bacterial infections

Side effects of I-Penam

Common
  • Injection site reactions (pain, swelling, redness)
  • Nausea
  • Vomiting
  • Headache
  • Rash

How to use I-Penam

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How I-Penam works

I-Penam is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to su... View More

What if you forget to take I-Penam?

If you miss a dose of I-Penam, please consult your doctor.

quick tipsQuick Tips
  • I-Penam is an antibiotic that's usually only given in the hospital for serious infections.
  • Inform your doctor if you are allergic to penicillin or if you are taking any seizure medication before starting treatment with this medication.
  • Diarrhea may occur as a side effect. Inform your doctor if you develop severe stomach pain or if you find blood in your stools.
  • Your doctor may monitor your kidney function and blood count while you are having treatment with this medication.
descriptionBrief Description

Indication

Cystic fibrosis, Intra-abdominal infections, Meningitis, Skin and skin structure infections, Diabetic foot infection

Administration

IV Administration Administer IV infusion over 15-30 minutes; administer IV bolus over 3-5 minutes

Adult Dose

Intravenous Intra-abdominal infections Adult: 1 g 8 hrly via IV inj over approx 3-5 min or infused over approx 15-30 min. Skin and skin structure i... View More

Child Dose

Children: IV 60 mg/kg/day, max 3 g/day q8h 120 mg/kg/day meningitis, max 6 g/day q8h Intravenous Intra-abdominal infections Child: >3mth ?50 kg:... View More

Renal Dose

Renal impairment: CrCl (ml/min) 26-50 Usual dose 12 hrly. 10-25 Half the usual dose 12 hrly. <10 Half the usual dose 24 hrly.

Contraindication

Hypersensitivity to meropenem, other carbapenems. History of anaphylactic reaction to β-lactams (e.g. penicillins, cephalosporins).

Mode of Action

Meropenem is a synthetic carbapenem beta-lactam antibiotic that exerts its bactericidal activity by inhibiting bacterial cell wall synthesis in gm+ve an... View More

Precaution

Patient w/ underlying CNS disorders (e.g. brain lesions, history of seizures. Not recommended for treatment of MRSA. Renal impairment. Childn. Pregnancy... View More

Side Effect

1-10% Constipation (1-7%),Diarrhea (4-5%),Nausea or vomiting (1-4%),Rash (2-3%; includes diaper-area moniliasis in pediatric patients),Headache (2%),In... View More

Interaction

Increased plasma concentration w/ probenecid. May decrease plasma levels of valproic acid thus, increasing the risk of seizures.

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More