Ifamide 2g is used in the treatment of different kinds of cancers. It is given alone or in combination with other chemotherapy medicines, radiotherapy a... View More
Uses of Ifamide 2g
Side effects of Ifamide 2g
How to use Ifamide 2g
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Ifamide 2g works
Ifamide 2g is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multip... View More
What if you forget to take Ifamide 2g?
If you miss a dose of Ifamide 2g, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to you... View More
Breast cancer, Lung cancer, Ovarian cancer, Lymphoma, Testicular cancer, Soft tissue sarcoma, Osteogenic sarcoma, Cervical cancer
IV Administration Slow IV infusion over 30 min, or continuous infusion over 5 d Mesna should be administered concomitantly (20% of the ifosfamide dose... View More
Intravenous Germ cell testicular carcinoma Adult: 1.2 g/m2/day for 5 days via slow infusion over at least 30 minutes, repeat treatment every 3 wk or a... View More
Safety and efficacy not established
Renal impairment: CrCl (ml/min) <10 Administer 75% of dose.
Hypersensitivity; severe bone-marrow depression. Pregnancy, lactation.
Mode of Action
Ifosfamide is converted to its active metabolites via hepatic microsomal enzymes. These active metabolites act as alkylating agents, disrupting DNA and ... View More
Hepatic or renal dysfunction, compromised bone marrow reserve. Use with mesna and ensure high oral/IV fluid intake to reduce urotoxic effects. Lactat... View More
>10% Alopecia (83%),Nausea (58%),Vomiting (58%),Leukopenia (50%),Hematuria (46%),Metabolic acidosis (31%),Thrombocytopenia (20%),CNS toxicity (12%),Neu... View More
Causes enhanced toxicity with allopurinol, cisplatin. Ifosfamide enhances the anticoagulant effect of warfarin. CYP2A6 inducers (e.g. amobarbital, pento... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More