Adult: PO: (age > 12 year) 10 mg, once daily.
Increased risk of nephrotoxicity with nephrotoxic drugs e.g. aminoglycosides, ciclosporin, NSAIDs, vancomycin, tacrolimus. Ibuprofen increases bioavaila... View More
Pregnancy; elderly; child; renal or hepatic impairment. HIV antibody testing to be performed before initiation due to possible resistance development in... View More
Adefovir dipivoxil is an acyclic nucleoside reverse transciptase inhibitor. The diester function is hydrolyzed and subsequently phosphorylated to the ac... View More
Mode of Action
Taken orally, without regard to food.
Chronic hepatitis B
Renal impairment: Haemodialysis patients: 10 mg every 7 days after dialysis. CrCl (ml/min) 30-49 10 mg every 48 hr. 10-29 10 mg every 72 hr.
Pregnancy Category Note
>10% Hematuria (11% vs 10% in placebo-treated),Asthenia (13% vs. 14% placebo),Hepatitis exacerbation (25%) 1-10% Nausea (5%),Flatulence (4%),Diarrh... View More
Adefovir Dipivoxil is contraindicated in patients with previously demonstrated hypersensitivity to any of the components of the product.