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Integril 220mg/10ml

Injection
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Incepta Pharmaceuticals Ltd.
Generic: Eptifibatide
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descriptionSafety Advices
AlcoholAlcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Integril 2. Please consult your doctor.
PregnancyPregnancy
SAFE IF PRESCRIBED
Integril 2 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, th... View More
BreastfeedingBreastfeeding
CAUTION
Integril 2 should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is... View More
DrivingDriving
NOT RELEVANT
Not relevant, as Integril 2 is intended for use in hospitalised patients.
KidneyKidney
CAUTION
Integril 2 should be used with caution in patients with kidney disease. Dose adjustment of Integril 2 may be needed. Please consult your doctor. Use of ... View More
LiverLiver
CONSULT YOUR DOCTOR
There is limited information available on the use of Integril 2 in patients with liver disease. Please consult your doctor. Use of Integril 2 is not rec... View More
descriptionMedical Overview

Introduction

Integril 2 is a blood thinner which prevents formation of harmful blood clots. It is used in the treatment of a heart attack and also prevents the clott... View More

Uses of Integril 2

  • Heart attack

Side effects of Integril 2

Common
  • Bleeding
  • Decreased blood pressure

How to use Integril 2

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Integril 2 works

Integril 2 is an antiplatelet medication. It works by preventing the platelets from sticking together, thereby decreasing the formation of harmful blood... View More

What if you forget to take Integril 2?

If you miss a dose of Integril 2, please consult your doctor.

quick tipsQuick Tips
  • It is usually given by your nurse or doctor as an infusion (drip) into a vein.
  • It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails or using sharp objects.
  • Notify your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
descriptionBrief Description

Indication

Myocardial infarction, Unstable angina, Angioplasty, Percutaneous coronary intervention (PCI)

Adult Dose

Intravenous Unstable angina Adult: 180 mcg/kg via IV inj followed by 2 mcg/kg per minute by IV infusion for up to 72 hr. If percutaneous coronary inte... View More

Renal Dose

Renal Impairment (CrCl <50 mL/min) ACS: 180 mcg/kg IV, THEN continuous infusion 1 mcg/kg/min PCI: 180 mcg/kg IV, THEN continuous infusion 1 mcg/... View More

Contraindication

Active bleeding, increased risk of haemorrhage including hemorrhagic disorders, cerebrovascular disorders, history of stroke, uncontrolled hypertension,... View More

Mode of Action

Eptifibatide is a cyclic heptapeptide which blocks the platelet glycoprotein IIb/IIIa receptor thus preventing platelet aggregation and thrombosis.

Precaution

Discontinue in case of serious uncontrolled bleeding, or if emergency surgery or thrombolytic therapy is required. Hepatic impairment, platelet counts <... View More

Side Effect

1-10% Bleeding (8%),Hypotension (7%),Thrombocytopenia (2.3%),Injection site reaction <1% Hypersensitivity,Intracranial hemorrhage,Pulmonary hemorrh... View More

Pregnancy Category Note

Pregnancy Category: B Lactation: excretion in milk unknown; use with caution

Interaction

Increased risk of bleeding w/ heparin, other anticoagulants, antiplatelet & thrombolytic agents.

descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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