Irotin 40 is used in the treatment of cancer of colon and rectum. It shows its working by stopping or slowing down the growth of cancer cells. Irotin 4... View More
Uses of Irotin 40
Side effects of Irotin 40
How to use Irotin 40
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Irotin 40 works
Irotin 40 is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase I) involved in DNA multiplication of the cancer... View More
What if you forget to take Irotin 40?
If you miss a dose of Irotin 40, please consult your doctor.
Carcinoma of the colon or rectum
Reconstitution: Dilute in 5% dextrose injection (preferred) or 0.9% sodium chloride injection to a final concentration of 0.12-2.8 mg/ml.
Intravenous Colorectal Cancer Indicated as first-line therapy (with 5-fluorouracil and leucovorin) for metastatic colorectal cancer (CRC); it is also ... View More
Patients with a known hypersensitivity to the drug or its excipients.
Mode of Action
Irinotecan, a derivative of camptothecin, works by inhibiting the enzyme topoisomerase I thereby interfering with the coiling and uncoiling of DNA durin... View More
Early diarrhea is usually transient and infrequently severe. It may be accompanied by cholinergic symptoms of rhinitis, increased salivation, miosis, la... View More
>10% Anemia (>90%),Leukopenia (>90%),Neutropenia (>90%),Thrombocytopenia (>90%),Elevated bilirubin (88%),Diarrhea (85%),Nausea (79%),Asthenia (70%),Abd... View More
Diuretics increase risks of dehydration secondary to vomiting/diarrhoea; prophylactic dexamethasone as an antiemetic may enhance lymphocytopenia; prochl... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More