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Isotrex
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Isotrex0.05mg/100ml

Gel
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GlaxoSmithKline
Generic: Isotretinoin 0.05% Topical
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descriptionSafety Advices
AlcoholAlcohol
No interaction found/established
PregnancyPregnancy
UNSAFE
Isotrex is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effe... View More
BreastfeedingBreastfeeding
CONSULT YOUR DOCTOR
Isotrex is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
DrivingDriving
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KidneyKidney
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descriptionMedical Overview

Introduction

Isotrex belongs to a group of medicines known as retinoids that are used to treat severe acne, which occur as pimples, in adults and adolescents from 12... View More

Uses of Isotrex

  • Acne

Side effects of Isotrex

Common
  • Application site reactions (burning, irritation, itching and redness)
  • Dry skin
  • Cracked lips

How to use Isotrex

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and ... View More

How Isotrex works

Isotrex is a derivative of vitamin A. It acts on glands (sebaceous) on your skin to reduce the production of a natural substance (sebum) that causes acn... View More

What if you forget to take Isotrex?

If you miss a dose of Isotrex, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your r... View More

quick tipsQuick Tips
  • You have been prescribed Isotrex for the treatment of acne.
  • Clean the area to be treated with water and a non-medicated soap, and let it dry for 20-30 minutes before applying Isotrex.
  • It may increase the severity of the lesions in the first few weeks of use. Continue using it as prescribed by your doctor.
  • It may cause stinging sensation or a feeling of warmth when you first start using it. Inform your doctor if this persists.
  • Avoid exposure to sunlight while using it as it increases the sensitivity of your skin. Use protective measures such as sun-cream or protective clothing... View More
  • Avoid face waxing and laser treatment while using this medicine as it makes your skin more fragile.
  • Do not use Isotrex if you are pregnant or breastfeeding.
  • Inform your doctor if excessive skin dryness or skin sensitivity take place.
descriptionBrief Description

Indication

Acne

Adult Dose

Topical/Cutaneous Acne Adult: As 0.05% gel: Apply sparingly once or twice daily. Effect is observed w/in 6-8 wk of treatment.

Contraindication

Pregnancy, lactation.

Mode of Action

Isotretinoin is a synthetic retinoid which reduces sebaceous gland size and sebum production. It also regulates cell proliferation and differentiation.

Precaution

Preexisting or predisposition to hypertriglyceridaemia (e.g. DM, obesity or increased alcohol intake). Monitor triglyceride levels. Monitor blood lipids... View More

Side Effect

Dryness of mucous membranes, dryness of skin with scaling, fragility, erythema, cheilitis, pruritus, epistaxis, conjunctivitis, dry sore mouth and palmo... View More

Interaction

Additive toxicity with vitamin A or its derivatives. Decreased efficacy of microdosed progesterone (use 2 forms of contraception). May increase risk of ... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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