Rheumatoid arthritis, Malaria, Systemic lupus erythematosus, SLE, Amoebiasis
Should be taken with food.
Malaria Prevention: 500 mg (300 mg base) PO once/week Non-chloroquine-resistant 1 g (600 mg base) PO, THEN 500 mg (300 mg base) PO 6-8 hours later... View More
Malaria Prophylaxis: 5 mg/kg PO q1Week Treatment 1st dose: 10 mg/kg PO x1 dose 6 hours after 1st dose: 5 mg/kg PO qDay x2 days
Renal impairment: May need to reduce dose in prolonged treatment.
Hypersensitivity, known or suspected resistant P. falciparum infection, porphyria, retinal damage, concurrent hepatotoxic drugs.
Mode of Action
Chloroquine is used for malarial prophylaxis (as a suppressive) and in managing acute attacks of malaria. It is highly active against erythrocytic forms... View More
Psoriasis, diseases of the haematopoietic or CNS systems, myasthenia gravis, hepatic or renal impairment, G6PD deficiency, epilepsy, childn. Pregnancy a... View More
Retinopathy, hair loss, photosensitivity, tinnitus, myopathy (long-term therapy). Diarrhea, Loss of appetite, Nausea, Stomach cramps, Vomiting, Psychosi... View More
Pregnancy Category Note
Pregnancy There are no adequate and well-controlled studies evaluating the safety and efficacy of chloroquine in pregnant women; usage during pregnancy... View More
Concomitant therapy with phenylbutazone predisposes to dermatitis, antagonises effect of neostigmine and pyridostigmine, reduces bioavailability of ampi... View More