HomeLab TestAnti-Jo-I
Overview
The Anti-Jo-1 test is a blood test used to detect anti-histidyl-tRNA synthetase antibodies. These antibodies are primarily associated with idiopathic inflammatory myopathies, particularly ...
Risk assessment
Risk Assessment
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Conditions Assessed:
- Polymyositis: Chronic muscle inflammation causing muscle weakness.
- Dermatomyositis: Similar to polymyositis but also i...
Ranges
Normal Range
- Negative: Anti-Jo-1 antibodies are not detected.
- Typically reported as "negative" or below a specific threshold (varies by laboratory).
Test result interpretation
Interpretation
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Negative Test:
- Anti-Jo-1 antibodies are absent.
- Does not rule out other causes of myopathy or autoimmune diseases.
-
Positive Test:
Sample types
Sample Type
- Blood Sample:
- Collected via venipuncture (from a vein in the arm).
- Serum is typically used for analysis.
Frequently Asked Questions
What are the symptoms of diseases associated with Anti-Jo-1?
How common are Anti-Jo-1 antibodies?
What is Anti-Jo-1?
What diseases are associated with Anti-Jo-1?
How is Anti-Jo-1-related disease treated?
What is the significance of a positive Anti-Jo-1 test?
What is the prognosis for patients with Anti-Jo-1 antibodies?
Can Anti-Jo-1 antibodies be present in other conditions?
Are there other myositis-specific antibodies?
How is the Anti-Jo-1 test performed?
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Anti-Jo-I
The test is done to find if these antibody is being produced as it can lead to many diseases starting usually with muscle weakness.
৳1200৳1500
20% OFF
Sample Type:
blood
Fasting Required:
No
Description
Anti-Jo-1 antibodies are autoantibodies directed against histidyl-tRNA synthetase, an enzyme involved in protein synthesis. The presence of these antibodies is strongly associated with polymyositis and dermatomyositis, which are types of inflammatory myopathies. Patients with anti-Jo-1 antibodies often present with muscle weakness, lung disease (interstitial lung disease), and joint pain. The test is part of the myositis-specific antibody panel used to diagnose and differentiate inflammatory muscle diseases. Detection of anti-Jo-1 antibodies ca....
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