Overview

The Factor V test is a blood test that measures the activity or presence of Factor V, a protein involved in the coagulation (blood clotting) process. It helps diagnose bleeding disorders or an increased risk of blood clots.

Risk Assessment

A Factor V test is often performed for:
Bleeding disorders: If a patient has unexplained or excessive bleeding.
Clotting disorders: If a patient has recurrent blood clots (deep vein thrombosis, pulmonary embolism).
Factor V Leiden mutation: A genetic condition that increases the risk of abnormal blood clot formation.
Liver disease: Since Factor V is produced by the liver, its deficiency may indicate liver dysfunction.

Normal Range

• Factor V Activity: Typically 50% – 150% of normal clotting activity.
• Values may slightly vary based on laboratory standards.

Interpretation of Results

Normal Factor V levels: Indicates normal clotting function.
Low Factor V levels: May suggest:

• Liver disease
• Disseminated Intravascular Coagulation (DIC)
• Vitamin K deficiency
• Factor V deficiency (a rare bleeding disorder)

High Factor V levels: May indicate:

• Increased risk of clotting disorders
• Inflammatory conditions

If the Factor V Leiden mutation is tested separately, a positive result suggests a higher risk of blood clots.

Sample Type

Blood sample (plasma) collected from a vein using a standard venipuncture procedure.