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Treponema Pallidum Antibody (TPAB)

Treponema Pallidum Antibody (TPAB) Test: Detecting Syphilis Infection.

Sample Type

blood

Fasting Required

Description

The Treponema Pallidum Antibody (TPAB) test is a blood test used to detect antibodies against Treponema pallidum, the bacterium responsible for syphilis. This test helps in diagnosing syphilis, especially in individuals who may not show symptoms but could still be infected. It is commonly used to screen and monitor syphilis infections in individuals.

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How our test process works!

Step 1

Sample Collection

Vaccinated Phlebotomists collects from syringe in the barcoded vials

Step 2

Sample Storage

Only vaccinated phelbos are assigned orders

Step 3

High Tech Facility

Lab ingests the sample into processing machines which are 100% automated

Step 4

Accurate Digital Reports

The reports are generated by the processing machines and clinically correlated by doctors

Overview

Overview:

Test Purpose: Detects antibodies against Treponema pallidum to help diagnose syphilis infection.
Antibodies Detected: The test looks for both IgM and IgG antibodies, which may appear in response to an infection by Treponema pallidum.

Risk Assessment

Risk Assessment:

Risk Factors:
- Unprotected sex with multiple partners
- Having a history of syphilis or other sexually transmitted infections (STIs)
- Men who have sex with men (MSM)
- Individuals with compromised immune systems (e.g., HIV-positive individuals)
- Drug users who share needles.

Normal Range

Normal Range:

The normal range for a TPAB test is negative, meaning no detectable antibodies to Treponema pallidum are present in the blood.

Interpretation of Results

Interpretation of Results:

Positive TPAB: A positive result typically indicates current or past syphilis infection. However, it can also be seen in people who have been treated for syphilis in the past or in cases of other conditions causing false positives.
Negative TPAB: A negative result suggests that there are no detectable antibodies to Treponema pallidum, indicating no active or past syphilis infection. However, a negative result in early infection might not be conclusive, as antibodies take time to develop.
Further Testing: If the TPAB is positive, follow-up tests like the VDRL (Venereal Disease Research Laboratory) or RPR (Rapid Plasma Reagin) test may be performed to confirm active syphilis. These tests detect antibodies related to syphilis in the blood and are more specific to current infections.

Sample Type