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Perigen IM

Injection-(5mg/ml)
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General Pharmaceuticals Ltd.

Generic: Haloperidol

1 x 1 amps
৳ 10.94
৳ 12.03
9% OFF

Medicine Overview of Perigen IM 5mg/ml Injection

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Introduction

Perigen IM is a prescription medicine used in the treatment of schizophrenia (a mental disorder in which a person develops unreal thoughts and behavior). It is also used to treat Tourette syndrome (chronic multiple motor and vocal problems and involuntary responses) in adults and children. Perigen IM can also be used for treating psychosis, mania, severe behavior problems in adults and children. It may be taken with or without food, preferably at the same time each day. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms. Some common side effects of this medicine include dry mouth, abnormality of voluntary movements, urinary retention, constipation, and muscle rigidity. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. Before taking it, inform your doctor if you are suffering from thyroid or kidney problems, epilepsy, Parkinson's disease, glaucoma, or any heart problems. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, cough, and/ or allergy medication. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly.

Uses of Perigen IM

  • Schizophrenia

Side effects of Perigen IM

Common
  • Abnormality of voluntary movements
  • Constipation
  • Dryness in mouth
  • Increased prolactin level in blood
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Sleepiness
  • Weight gain

How to use Perigen IM

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Perigen IM may be taken with or without food, but it is better to take it at a fixed time.

How Perigen IM works

Perigen IM is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.

Quick Tips

  • Perigen IM helps treat schizophrenia.
  • It is less likely to cause weight gain as compared to other similar medicines.
  • Use caution while driving or doing anything that requires concentration as Perigen IM may cause dizziness and sleepiness.
  • Avoid drinking alcohol while taking this medicine as it can cause increased dizziness.
  • Inform your doctor if you experience any abnormal movements or have difficulty controlling movements.
  • It may affect how your body regulates your temperature. Avoid getting dehydrated and drink plenty of fluids.
  • Your doctor may check your heart function and level of electrolytes such as sodium and magnesium before you start treatment with this medicine and regularly thereafter.
  • Do not stop taking Perigen IM without talking to your doctor first as it may cause worsening of symptoms.

Brief Description

Indication

Schizophrenia, Delirium, Hiccups, Acute psychosis, Hyperactivity, Aggression, Agitation and confusion, Tic disorders, Tourette syndrome, Chorea, Nausea and vomiting, Dementia.

Administration

May be taken with or without food. May be taken w/ meals to minimise GI irritation.

Adult Dose

Oral Psychoses Adult: 0.5-5 mg bid/tid, may increase up to 100 mg daily in severe or resistant cases. Usual maintenance: 3-10 mg daily. Tourette's syndrome; Severe tics Adult: Initially, 0.5-1.5 mg tid. Up to 30 mg daily may be required in Tourette's syndrome; adjust dose carefully to obtain optimum response; usual maintenance: 4 mg daily. Short-term adjunct in severe anxiety or behavioral disturbances Adult: 0.5 mg bid. Restlessness and confusion Adult: 1-3 mg every 8 hr. Intractable hiccup Adult: 1.5 mg tid, adjust according to response. Intramuscular Acute psychosis Adult: Doses range from 2-10 mg, may be given every hr or at intervals of 4-8 hr, until symptoms are controlled. Max: 18 mg/day. For emergency control of severely disturbed patients: Up to 18 mg may be given IV/IM. Elderly: PO: Lower initial doses and more gradual adjustments recommended; 0.25-0.5 mg PO q8-12hr initially IM (prompt-acting): Lower adult doses and longer dosing intervals recommended compared with typical adult doses

Child Dose

<3 years: Safety and efficacy not established Psychosis/Sedation 3-12 years (15-40 kg): 0.25-0.5 mg/day PO divided q8-12hr initially; may be increased by 0.5 mg/day every 5-7 days PRN; maintenance: 0.05-0.15 mg/kg/day PO divided q8-12hr 6-12 years: Lactate (prompt-acting): 1-3 mg IM q4-8hr PRN; not to exceed 0.15 mg/kg/day >12 years: Moderate disease, 0.5-2 mg PO q8-12hr initially; severe disease, 3-5 mg PO q8-12hr; not to exceed 30 mg/day Tourette Disorder 3-12 years: 0.5 mg/day PO initially; dose increased by 0.5 mg every 5-7 days until therapeutic effect achieved, then reduced to lowest effective maintenance level of 0.05-0.075 mg/kg/day PO divided q8-12hr >12 years: 0.5-2 mg PO q8-12hr initially; if severe symptoms necessitate increased dosage, titrate upward to 3-5 mg PO q8-12hr; if patient remains inadequately controlled, daily doses up to 100 mg have been used (safety not determined) Behavioral Disorders 3-12 years: 0.5 mg/day PO initially; dose increased PRN by 0.5 mg every 5-7 days until therapeutic effect achieved, then reduced to lowest effective maintenance level of 0.05-0.075 mg/kg/day PO divided q8-12hr Acute Agitation <12 years: Safety and efficacy not established >12 years: 0.5-3 mg PO, repeated in 1 hour PRN; alternatively, 2-5 mg IM, repeated in 1 hr PRN

Contraindication

Severe toxic CNS depression; preexisting coma; Parkinson's disease; lactation.

Mode of Action

Haloperidol blocks postsynaptic dopamine D1 and D2 receptors in the mesolimbic system and decreases the release of hypothalamic and hypophyseal hormones. It produces calmness and reduces aggressiveness with disappearance of hallucinations and delusions.

Precaution

Parkinsonism; epilepsy, allergy, angle-closure glaucoma, benign prostatic hyperplasia; severe cardiac or hepatic disease; extremes in temp (hot and cold weather); presence of acute infections or leucopenia; hyperthyroidism; pregnancy, elderly, children. Patients receiving anticoagulants. Discontinue upon signs of neurological toxicity in patients taking haloperidol and lithium. Lactation: Drug enters breast milk; not recommended

Side Effect

Extrapyramidal symptoms Akathisia,Dystonia,Muscle stiffness,Neuroleptic malignant syndrome (NMS; infrequent but serious),Parkinsonism,Tardive dyskinesia Common Anticholinergic effects,Sedation,Weight gain,Erectile dysfunction,Oligomenorrhea or amenorrhea Less common Orthostatic hypotension (after IM injection), tachycardia Agitation, anxiety, cerebral edema, depression, dizziness, euphoria, headache, insomnia, poikilothermia, restlessness, weakness, confusion Anorexia, constipation, dyspepsia, ileus, decreased gag reflex Lens opacities (prolonged use) Uncommon ECG changes,Photosensitivity,Pruritus,Diarrhea,Blood dyscrasia,Ejaculatory disorder,Galactorrhea Rare Seizure,Cholestatic jaundice,Priapism Potentially Fatal: Neuroleptic malignant syndrome

Interaction

Carbamazepine and rifampicin reduce plasma concentrations. Symptoms of CNS depression may be enhanced by CNS depressants e.g. alcohol, hypnotics, general anaesthetics, anxiolytics and opioids. May reduce antihypertensive action of guanethidine. May increase risk of arrhythmia when used with drugs that prolong QT interval or diuretics that can cause electrolyte imbalance. May increase plasma levels of haloperidol when used with clozapine or chlorpromazine. Potentially Fatal: Increases lithium blood levels and may predispose to neuroleptic malignant syndrome.

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What is the price of Perigen IM in Bangladesh?

The latest price of Perigen IM in Bangladesh is 10.94. You can buy Perigen IM at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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UNSAFE
Perigen IM may cause excessive drowsiness with alcohol.
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CONSULT YOUR DOCTOR
Perigen IM may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
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CONSULT YOUR DOCTOR
Perigen IM is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. If Perigen IM is used, monitor the baby for excessive sleepiness.
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UNSAFE
Perigen IM may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
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SAFE IF PRESCRIBED
Perigen IM is safe to use in patients with kidney disease. No dose adjustment of Perigen IM is recommended. However, patients with severe kidney disease may need to be started at a lower dose as it may cause excessive sleepiness in these patients.
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CAUTION
Perigen IM should be used with caution in patients with liver disease. Dose adjustment of Perigen IM may be needed. Please consult your doctor.
Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.