12-24 Hours
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Perkirol 0.25
Square Pharmaceuticals PLC.
Generic: Ropinirole
Safety Advices
বাংলা
English
CAUTION
Caution is advised when consuming alcohol with Perkirol 0.25. Please consult your doctor.
CONSULT YOUR DOCTOR
Perkirol 0.25 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Perkirol 0.25 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Perkirol 0.25 suppresses serum prolactin and may interfere with breastfeeding.
UNSAFE
Perkirol 0.25 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CAUTION
Perkirol 0.25 should be used with caution in patients with severe kidney disease. Dose adjustment of Perkirol 0.25 may be needed. Please consult your doctor.
CAUTION
Perkirol 0.25 should be used with caution in patients with liver disease. Dose adjustment of Perkirol 0.25 may be needed. Please consult your doctor.
Use of Perkirol 0.25 is not recommended in patients with the severe liver disease.
Medicine Overview of Perkirol 0.25 0.25mg Tablet
Introduction
Perkirol 0.25 is a prescription medicine used in the treatment of Parkinson's disease and restless leg syndrome (an urge to move the legs usually accompanied or caused by uncomfortable and unpleasant leg sensations). It helps to treat excessive shaking by slowing down the body movements. Perkirol 0.25 should be taken with food. However, take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you...
... Show moreUses of Perkirol 0.25
- Parkinson's disease
- Restless leg syndrome
Side effects of Perkirol 0.25
Common
- Headache
- Dizziness
- Fainting
- Sleepiness
- Vomiting
- Weakness
- Nausea
- Edema (swelling)
- Abnormality of voluntary movements
- Indigestion
- Hallucination
- Confusion
- Viral infection
How to use Perkirol 0.25
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Perkirol 0.25 is to be taken with food.
How Perkirol 0.25 works
Perkirol 0.25 works by increasing the action of dopamine, a chemical messenger that is needed to control movement in the brain.
Quick Tips
- You have been prescribed Perkirol 0.25 to treat your symptoms of Parkinson's disease and/or restless leg syndrome.
- It can be taken with or without food. Taking it with food may reduce nausea.
- For restless leg syndrome, take this medicine 2 to 3 hours before bedtime.
- Avoid activities that require you to be alert, such as driving a car until you know how this medication affects you.
- When you first start taking Perkirol 0.25, it may cause sudden drop in your blood pressure when you change positions. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
- Inform your doctor if you develop compulsive behaviors that are hard to control, such as binge eating, gambling, spending money, and sexual urges.
- Talk to your doctor in case you develop hallucinations or other changes in your behavior.
- Do not stop taking the medication suddenly without talking to your doctor.
Brief Description
Indication
Parkinson's disease, Restless leg syndrome
Administration
May be taken with or without food. May be taken w/ meals to reduce occurrence of nausea.
Adult Dose
Oral As monotherapy in Parkinson's disease Adult: Initially, 250 mcg tid, may increase by 750 mcg at wkly intervals for the first 4 wk. Subsequent increments can be made in steps of 1.5 mg at wkly intervals up to 9 mg/day, then in steps of 3 mg at wkly intervals. Usual dose ranges from 3-9 mg daily. Max: 24 mg/day. Higher dose may be necessary if used in conjunction with levodopa. Gradual withdrawal is recommended. Restless leg syndrome Adult: Initially, 250 mcg daily for 2 days, taken 1-3 hr before bedtime. May increase to 500 mcg daily for the next...
... Show moreContraindication
Lactation.
Mode of Action
Ropinirole is a non-ergot dopamine D2-agonist with similar actions to those of bromocriptine. It is used in the management of Parkinson's disease, either alone or as an adjunct to levodopa.
Precaution
Pregnancy. May impair ability to drive or operate machinery. Withdrawal should be gradual. Hepatic or renal impairment. May cause daytime sleepiness or episodes of falling asleep during activities. May cause or worsen pre-existing dyskinesia.
Side Effect
>10%
Nausea (40-60%),Dizziness (6-40%),Somnolence (11-40%),Syncope (1-12%),Vomiting (12%),Fatigue (8-11%),Viral infection (11%),Dyspepsia (10%)
1-10%
Hypertension (5%),Flushing (3%),Orthostasis (1-6%),Chest pain (4%),Palpitation (3%),Extrasystoles (2%),Tachycardia (2%),Hyperhidrosis (3%),Abnormal pain (3-7%),Anorexia (4%),Flatulence (3%),Malaise (3%),Hypoesthesia (4%),Urinary tract infection (5%),Impotence (3%),Alkaline phosphatase (3%),Abnormal vision (6%),Xerophthalmia (2%),Increased diaphoresis (3-6%)
<1%
Agitation,Aneurysm,Aphasia,Bradycardia,Cardiac arrest,Valvulopathy,Cellulitis,Colitis,Delusion,Delirium,Diaphoresis,Dyspnea,Ulceration,Glaucoma,Psychotic-like behavior,Impulse control/compulsive behavior,Withdrawal-emergent hyperpyrexia and confusion,Melanoma,Fibrotic complications
Interaction
Inhibitors of CYP1A2 e.g. cimetidine, ciprofloxacin, erythromycin, fluvoxamine, isoniazid, ritonavir and zileuton may increase serum concentrations of ropinirole. Oestrogens and tobacco smoking may decrease clearance of ropinirole. Efficacy may be reduced by dopamine antagonists such as phenothiazines and metoclopramide.
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