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Santinal MR 200
Unimed Unihealth Pharmaceuticals Ltd.
Generic: Dipyridamole
Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Santinal MR 200.
SAFE IF PRESCRIBED
Santinal MR 200 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Santinal MR 200 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
UNSAFE
Santinal MR 200 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
SAFE IF PRESCRIBED
Santinal MR 200 is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Santinal MR 200 may not be needed in these patients. Please consult your doctor.
SAFE IF PRESCRIBED
Santinal MR 200 is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Santinal MR 200 may not be needed in these patients. Please consult your doctor.
Medicine Overview of Santinal MR 200mg Capsule
Introduction
Santinal MR 200 is an antiplatelet medication used to prevent stroke. It is used to prevent blood clotting after heart valve replacement. It also reduces the risk of having another stroke in people who have already suffered a stroke. Santinal MR 200 should be taken as advised by the doctor. You should take it on an empty stomach and at a fixed time. This medicine should not be stopped abruptly without consulting the doctor. Use of this medicine may increase your risk of bleeding. Let your doctor know immediately if you see pinpoint rash or blood in your vomits, urine,...
... Show moreUses of Santinal MR 200
- Stroke
Side effects of Santinal MR 200
Common
- Headache
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Dizziness
- Nausea
- Diarrhea
- Decreased blood pressure
How to use Santinal MR 200
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Santinal MR 200 is to be taken empty stomach.
How Santinal MR 200 works
Santinal MR 200 is an antiplatelet medication. It works by preventing the platelets from sticking together, thereby decreasing the formation of harmful blood clots.
What if you forget to take Santinal MR 200?
If you miss a dose of Santinal MR 200, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Do not discontinue use without consulting your doctor.
- It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails or using sharp objects.
- If you are going to have a surgery or dental treatment, you may be asked to stop taking Santinal MR 200 temporarily.
- Headache is a common side effect, but it often goes away after the first week of use.
Brief Description
Indication
Stroke, Thromboembolism, Transient ischaemic attack
Administration
Should be taken on an empty stomach. Take on an empty stomach 1 hr before meals. May be taken w/ meals to reduce GI discomfort.
Adult Dose
Oral
Thromboembolism Prophylaxis Post-Cardiac Valve Replacement
Adult: 75-100 mg PO q6hr as adjunct to warfarin
Child Dose
Oral
Thromboembolism Prophylaxis Post-Cardiac Valve Replacement
Child: 3-6 mg/kg/day PO divided q6-8hr
Contraindication
Hypersensitivity. Peptic ulcer.
Mode of Action
Dipyridamole causes an accumulation of adenosine, adenine nucleotides and cAMP by inhibiting the activity of adenosine deaminase and phosphodiesterase thus inhibiting platelet aggregation and may cause vasodilation.
Precaution
In patients with rapidly worsening angina, subvalvular aortic stenosis, haemodynamic instability associated with recent MI or coagulation disorders esp when given IV during myocardial imaging. Hypotension, unstable angina, aortic stenosis. Pregnancy and lactation. Safety and efficacy are not established in childn < 12 yrs.
Lactation: enters breast milk; use with caution
Side Effect
>10%
Chest pain (20%),Abnormal ECG (15.9%),Dizziness (12%)
1-10%
ST-T changes (7.5%),Abdominal discomfort, oral (6.1%),Extrasystole (5%),Flushing (3.4%),Generalized pain (2.6%),Headache, oral (2.3%)
Frequency Not Defined
Myocardial infarction (rare),Ventricular arrhythmia (rare),Bronchospasm (rare),Dyspnea
Pregnancy Category Note
Pregnancy Category: B
Lactation: enters breast milk; use with caution
Interaction
Aminophylline may reverse vasodilatation effect. Useful combination with aspirin in prevention of thromboembolism. Efficacy reduced by concurrent admin of antacids. Concurrent use may increase the cardiotoxic effects of adenosine.
Potentially Fatal: Potentiates effects of oral anticoagulants and antiarrhythmic agents.
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