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Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
Serontin may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Serontin is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
UNSAFE
Serontin may cause side effects which could affect your ability to drive.
CONSULT YOUR DOCTOR
There is limited information available on the use of Serontin in patients with kidney disease. Please consult your doctor.
CONSULT YOUR DOCTOR
There is limited information available on the use of Serontin in patients with liver disease. Please consult your doctor.
Medicine Overview of Serontin 5gm/100ml Syrup
Uses of Serontin
- Epilepsy/Seizures
Side effects of Serontin
Common
- Nausea
- Vomiting
- Fatigue
- Indigestion
- Stomach pain
- Dizziness
- Lightheadedness
- Diarrhea
- Weight loss
- Headache
- Loss of appetite
- Hiccup
How to use Serontin
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Serontin may be taken with or without food, but it is better to take it at a fixed time.
How Serontin works
Serontin is an anticonvulsant medicine. It works by binding with the T-type voltage sensitive calcium channels to regulate the entrance for calcium ions in the nerves and brain. In this way, it decreases the hyperactivity of the brain and nerves. Thus, it works on the nervous system to treat seizures (fits).
Quick Tips
- Take it only as per dose and duration prescribed by your doctor.
- It may cause dizziness. Do not drive or do anything that requires mental focus until you know how Absenz Syrup affects you.
- Your doctor may get regular tests done to monitor your kidney function, liver function, and the level of blood cells in your blood.
- Inform your doctor if you notice changes in your mood, behavior or if you have suicidal thoughts while taking Absenz Syrup.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
- Do not stop taking medication suddenly without talking to your doctor as it can worsen the seizures.
Brief Description
Indication
Absence seizures
Administration
May be taken with or without food.
Adult Dose
Oral
Absence seizures
Adult: Initially, 500 mg daily, may increase in steps of 250 mg at intervals of 4-7 days. Usual dose: 1-1.5 g daily.
Optimum plasma concentration: 40-100 mg/L (300-700 micromol/L).
Max: Up to 2 g in some patients. Strict supervision is recommended if dose >1.5 g daily.
Hepatic Impairment
Monitor closely
Child Dose
Child: 6 yr: Initially, 500 mg daily, may increase in steps of 250 mg at intervals of 4-7 days.
Usual dose: 1-1.5 g daily. Max: <6 yr: Up to 1 g/day and ?6 yr: 2 g/day .
Renal Dose
Renal Impairment
Monitor closely
Contraindication
Hypersensitivity. Pregnancy and lactation.
Mode of Action
Ethosuximide is used mainly in the management of absence (petite mal) seizures. It is usually ineffective in the management of partial seizures with complex symptomatology or tonic-clonic seizures.
Precaution
Hepatic or renal impairment, porphyria. Complete blood cell count, liver function tests, and urinalysis should be performed periodically. May increase the risk of grand mal seizures when used alone in mixed types of epilepsy. Avoid sudden withdrawal. May impair ability to drive or operate machinery.
Lactation: enters breast milk; use with caution (AAP Committee states "compatible with nursing")
Side Effect
Common
Dizziness,Headache,Somnolence,Anorexia,Diarrhea,GI upset,Nausea,Vomiting
Less Common
Ataxia, confusion, drowsiness, sleep disturbance,Gum hypertrophy, hiccoughs, swelling of tongue,Blood dyscrasias including aplastic anemia,Allergic reaction,Urticaria,Pruritic erythematous rashes,Blurred vision, myopia
Rare
Psychosis,Seizure,Suicidal thoughts and behavior,Stevens-Johnson syndrome,Systemic lupus erythematosus,Hirsutism
Pregnancy Category Note
Pregnancy Category: C
Lactation: enters breast milk; use with caution (AAP Committee states "compatible with nursing")
Interaction
Isoniazid may increase the serum concentration of ethosuximide, leading to toxicity. Antipsychotics, antidepressants, MAOIs, and mefloquine may antagonise anticonvulsant effects of ethosuximide. Plasma conc of ethosuximide may be reduced by carbamazepine, phenobarbital, phenytoin, and primidone; and affected by valproate. Chloroquine or hydroxychloroquine may increase risk of convulsions. Isoniazid.
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