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Slipam 15
General Pharmaceuticals Ltd.
Generic: Flurazepam
Safety Advices
বাংলা
English
UNSAFE
Slipam 15 may cause excessive drowsiness with alcohol.
UNSAFE
Slipam 15 is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
CONSULT YOUR DOCTOR
Slipam 15 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
UNSAFE
Slipam 15 may cause side effects which could affect your ability to drive.
As Slipam 15 may cause side effects such as reduced alertness, confusion, tiredness, dizziness, poor muscle coordination and this may affect your ability to drive.
SAFE IF PRESCRIBED
Slipam 15 is safe to use in patients with kidney disease. No dose adjustment of Slipam 15 is recommended.
However, talk to your doctor if you have any underlying kidney disease.
CAUTION
Slipam 15 should be used with caution in patients with liver disease. Dose adjustment of Slipam 15 may be needed. Please consult your doctor.
Use of Slipam 15 is not recommended in patients with severe liver disease.
Medicine Overview of Slipam 15mg Capsule
Introduction
Slipam 15 belongs to a class of medicines known as benzodiazepines. It is a prescription medicine used to treat insomnia. It relaxes the brain and helps to treat people who have problems with their sleeping habits. Slipam 15 may be taken with or without food. However, take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor as it has a high potential of habit-forming. If you have missed any doses, take it as soon as you...
... Show moreUses of Slipam 15
- Insomnia
Side effects of Slipam 15
Common
- Dizziness
- Drowsiness
- Impaired coordination
- Lightheadedness
How to use Slipam 15
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Slipam 15 may be taken with or without food, but it is better to take it at a fixed time.
How Slipam 15 works
Slipam 15 is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.
What if you forget to take Slipam 15?
If you miss a dose of Slipam 15, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- If you are taking Slipam 15 for the treatment of insomnia, it should not be used for more than 4 weeks.
- Take it 30 to 45 minutes before bedtime and only when you have time to sleep for at least 7 hours.
- The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
- Never share your medication with any other person who also has a sleep problem.
- It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
- Avoid consuming alcohol as it may increase dizziness and drowsiness.
- Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
- If you have been taking this medicine for a long time, regular monitoring of blood and liver functions may be required.
- Stop taking medication and inform your doctor If you experience sleep-driving or memory loss.
- Inform your doctor if you are suffering from depression, as this medicine may worsen the symptoms of depression.
- Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.
Brief Description
Indication
Insomnia
Administration
May be taken with or without food.
Adult Dose
Oral
Short-term management of insomnia
Adult: 15-30 mg at night.
Elderly: Max: 15 mg at night.
Child Dose
Oral
Short-term management of insomnia
Child: >15 yr 15 mg at night.
Elderly: Max: 15 mg at night.
Contraindication
Hypersensitivity; porphyria. Pregnancy (3rd trimester); neonates.
Mode of Action
Flurazepam is a long-acting benzodiazepine which binds to stereospecific benzodiazepine receptors on the postsynaptic GABA neuron w/in the CNS, including the limbic system, reticular formation. It enhances the inhibitory effect of GABA on neuronal excitability by increasing neuronal membrane permeability to Cl ions, thus resulting in hyperpolarisation and stabilisation.
Precaution
Chronic pulmonary insufficiency; elderly or debilitated patients; muscle weakness, impaired liver or kidney function; drowsiness may affect skilled tasks; monitor cardio-respiratory function when used for deep sedation; personality disorders or organic brain changes; history of alcohol or drug addiction. Respiratory depression and hypotension with parenteral admin. Dependence; lactation. Safety and efficacy are not proven in children <15 yr.
Lactation: Excretion in milk unknown; not recommended
Side Effect
Common
Ataxia,Dizziness,Drowsiness,Lethargy,Light-headedness
Less Common
Chest pain, palpitations,Headache, irritability, nervousness, weakness,GI complaints,Myalgia,GU complaints
Rare
Elevations of AST, ALT, bilirubin (T&D), alk phos
Pregnancy Category Note
Pregnancy Category: X
Lactation: Excretion in milk unknown; not recommended
Minor tranquilizers should be avoided in 1st trimester of pregnancy due to increased risk of congenital malformations
Maternal use shortly before delivery is associated with floppy infant syndrome (good and consistent evidence)
Prenatal benzodiazepine exposure slightly increased oral cleft risk (limited or inconsistent evidence)
Interaction
May enhance CNS depressant effect w/ antidepressants, antipsychotics, general anaesth, hypnotics or sedatives, opioid analgesics. Flurazepam clearance may be reduced by cimetidine, and may be increased by rifampicin.
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