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Stopain
Beximco Pharmaceuticals Ltd.
Generic: Pentazocine Hydrochloride
Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Stopain.
CONSULT YOUR DOCTOR
Stopain may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Stopain is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
UNSAFE
Stopain may cause side effects which could affect your ability to drive.
Stopain may cause sedation especially if taken with alcohol. This may impair your driving ability.
CAUTION
Stopain should be used with caution in patients with kidney disease. Dose adjustment of Stopain may be needed. Please consult your doctor.
CAUTION
Stopain should be used with caution in patients with liver disease. Dose adjustment of Stopain may be needed. Please consult your doctor.
Medicine Overview of Stopain 25mg Tablet
Introduction
Stopain is a pain relieving medicine. It is used to manage persistent, moderate to severe chronic pain that requires continuous, around-the-clock treatment for an extended period of time. Stopain is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. The most common side effects of this medicine include injection site reactions (such as pain, redness, and swelling), headache, drowsiness, fatigue, vomiting, constipation, dry mouth, and sweating. If any of these side effects persist or get...
... Show moreUses of Stopain
- Moderate to severe pain
Side effects of Stopain
Common
- Headache
- Dizziness
- Sleepiness
- Vomiting
- Nausea
- Constipation
How to use Stopain
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Stopain works
Stopain is an opioid analgesic (pain reliever) which works by blocking transmission of pain signals to the brain to lower pain perception.
What if you forget to take Stopain?
If you miss a dose of Stopain, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Use Stopain as instructed by your doctor. Never take in greater amounts or more often than prescribed.
- It causes sleepiness or drowsiness. If this happens to you, do not drive or use machinery.
- Avoid consuming alcohol when taking the Stopain, as it may cause excessive sleepiness or drowsiness.
- Inform your doctor if you have ever been diagnosed with kidney or liver problems.
- Store opioid pain relievers in a safe place and out of reach of others.
Brief Description
Indication
Moderate to severe pain
Administration
Should be taken with food. Take after meals.
Adult Dose
Oral
Moderate to severe pain
Adult: 50-100 mg every 3-4 hrs; max 600 mg daily.
Hepatic impairment: Reduce dose or avoid in liver disease.
Child Dose
Oral
Moderate to severe pain
Child: 6-12 yr: 25 mg every 3-4 hr.
Renal Dose
Renal impairment:
CrCl (ml/min) Dosage Recommendation
10-50 75% normal dose.
<10 50% normal dose.
Contraindication
Head injury; narcotic dependence; respiratory depression; raised intracranial pressure; MI; heart failure; arterial or pulmonary hypertension; porphyria; pregnancy (prolonged use or high doses at term).
Mode of Action
Pentazocine is a benzomorphan derivative with mixed opioid agonist and antagonist actions. It alters perception of and response to pain and produces generalised CNS depression by binding to opiate receptors in the CNS and acting as a partial agonist/antagonist.
Precaution
May precipitate withdrawal in narcotic addicts. Impaired respiratory, renal and hepatic function; morbidly obese patients; thyroid dysfunction; prostatic hyperplasia or urinary stricture; biliary tract impairment; adrenal insufficiency (including Addison's disease); abdominal conditions. Elderly or debilitated patients; seizure-prone patients; children and infants (safety and efficacy not established in <1 yr); lactation. May impair ability to drive or operate machinery. Administer IM rather than SC (when frequent inj are needed) and inj sites should be varied.
Lactation: unknown if excreted in breast milk, use caution
Side Effect
Physical dependence; sedation, dizziness, euphoria, lightheadedness, alterations of mood; respiratory depression; visual hallucinations, disorientation, confusion; hypertension, tachycardia, circulatory depression; shock; hypotension; nausea, vomiting, constipation; seizures, diaphoresis; rash; blood dyscrasias; local tissue damages (SC), muscle fibrosis (IM).
Potentially Fatal: Respiratory depression, hypotension, circulatory failure, deepening coma, convulsions.
Pregnancy Category Note
Pregnancy Category: C; D if used for prolonged periods or near term
Interaction
Depressant affects potentiated by alcohol, CNS depressants; concurrent use with fluoxetine may lead to diaphoresis, ataxia flushing and tremor associated with serotonin syndrome.
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