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Safety Advices
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UNSAFE
Thalidon 25 may cause excessive drowsiness with alcohol.
CONSULT YOUR DOCTOR
Thalidon 25 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Thalidon 25 is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
UNSAFE
Thalidon 25 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CAUTION
Thalidon 25 should be used with caution in patients with severe kidney disease. Dose adjustment of Thalidon 25 may be needed. Please consult your doctor.
Use of Thalidon 25 is not recommended in these patients.
CAUTION
Thalidon 25 should be used with caution in patients with liver disease. Dose adjustment of Thalidon 25 may be needed. Please consult your doctor.
Use of Thalidon 25 is not recommended in patients with severe liver disease.
Medicine Overview of Thalidon 25mg Tablet
Introduction
Thalidon 25 is a diuretic (water pill) medicine used to treat hypertension (high blood pressure). This medicine reduces excess fluid levels in the body and treats edema (fluid overload) associated with heart, liver, kidney, or lung disease. Thalidon 25 makes you lose excess water through urine. It may be used alone or in combination with other medicines. This medicine should be taken only during day time to avoid frequent urination at night. You must take this medicine in the dose and duration as advised by the doctor and never stop it abruptly without consulting the doctor. Most people with high...
... Show moreUses of Thalidon 25
- Hypertension (high blood pressure)
Side effects of Thalidon 25
Common
- Headache
- Nausea
- Increased blood uric acid
- Decreased potassium level in blood
- Glucose intolerance
- Altered blood lipid level
How to use Thalidon 25
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Thalidon 25 is to be taken with food.
How Thalidon 25 works
Thalidon 25 is a diuretic which lowers blood pressure by removing extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.
What if you forget to take Thalidon 25?
If you miss a dose of Thalidon 25, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Take it in the morning with breakfast to avoid getting up at night to urinate.
- It makes you feel dizzy. Avoid driving and attention requiring activity until you know how it affects you.
- Avoid alcohol intake while taking CTD 12.5 Tablet as it may increase the dizziness.
- It may cause a sudden drop of sodium level in blood. Avoid low sodium diet while you are taking this medication.
- Monitor your blood pressure after starting CTD 12.5 Tablet, and notify your doctor if it does not lower down.
- Notify your doctor if you experience dizziness, tiredness, or muscle weakness that does not go away.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Brief Description
Indication
Hypertension, Oedema, Diabetes insipidus, Congestive heart failure
Administration
Should be taken with food. Take during meals.
Adult Dose
Hypertension
25-100 mg/day PO; usual range, 12.5-25 mg/day
Edema
50-100 mg/day PO or 100 mg PO every other day; not to exceed 200 mg/day
Heart Failure
12.5-25 mg/day PO; not to exceed 100 mg/day
Renal Dose
Renal impairment
CrCl 10 mL/min: Dose adjustment not necessary
Contraindication
Severe renal impairment or anuria. Severe hepatic impairment, addison's disease, preexisting hypercalcaemia, asthma; hypersensitivity; severe allergy. Pregnancy and lactation.
Mode of Action
Chlortalidone is an oral, long acting antihypertensive/diuretic. It is a monosulfamyl diuretic that acts by enhancing the excretion of sodium and chloride ions, and water by interfering with the transport of sodium ions across the renal tubular epithelium. Their primary site of action appears to be at the cortical diluting segment in the nephron of the loop of Henle.
Precaution
Existing fluid and electrolyte disturbances, hepatic cirrhosis, severe heart failure, hyperuricaemia, mild to moderate renal impairment. Elderly. Monitor fluid and electrolyte balance. Kidney or liver disease; diabetes; gout; hyperlipidaemia and ventricular extra systoles.
Lactation: Drug enters breast milk; not recommended (American Academy of Pediatrics states that it is "compatible with nursing")
Side Effect
Common
Cardiovascular: Hypotension, vasculitis
Dermatologic: Photosensitivity, phototoxicity
Endocrine/metabolic: Electrolyte abnormalities, hyperglycemia, hyperuricemia
Gastrointestinal: Constipation, diarrhea, loss of appetite, nausea, vomiting
Musculoskeletal: Spasticity
Neurologic: Dizziness, headache, paresthesia
Ophthalmologic: Blurred vision, xanthopsia
Psychiatric: Restlessness
Reproductive: Impotence
Potentially Fatal: Rare. Severe hyponatraemia and idiosyncratic hypersensitivity.
Pregnancy Category Note
Pregnancy Available data over decades from observational studies and reports with chlorthalidone use in pregnant women have not identified a drug-associated risk of major birth defects or miscarriage; however, adverse fetal outcomes, including fetal or neonatal jaundice, thrombocytopenia, hypoglycemia, and electrolyte abnormalities reported following maternal use of thiazide diuretics Drug not for use as first-line therapy to treat hypertension in pregnancy; advise pregnant women of potential risk to fetus Hypertension in pregnancy increases maternal risk for pre-eclampsia, gestational diabetes, premature delivery, and delivery complications (eg, need for cesarean section, and post-partum hemorrhage); hypertension increases fetal risk for intrauterine growth restriction...
... Show moreInteraction
NSAIDs antagonise hypotensive action. Suppresses action of oral anticoagulants due to reduced prothrombin activity. Increased risk of hypokalaemia when corticosteroids are given concurrently.
Potentially Fatal: Potentiates bone marrow suppression caused by anticancer drugs. Diuretic-induced vol depletion can potentiate aminoglycoside nephrotoxicity. Impairs action of oral hypoglycaemic agents. Enhances digitalis toxicity due to hypokalaemia. vol depletion enhances lithium toxicity, conversely, sudden withdrawal of diuretics may result in subtherapeutic levels of circulating lithium. Prolonged paralysis with tubocurarine due to hypokalaemia.
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Disclaimer
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.
