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Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Varni.
CONSULT YOUR DOCTOR
Varni may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CAUTION
Varni should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
UNSAFE
Varni may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CAUTION
Varni should be used with caution in patients with kidney disease. Dose adjustment of Varni may be needed. Please consult your doctor.
SAFE IF PRESCRIBED
Varni is safe to use in patients with liver disease. No dose adjustment of Varni is recommended.
Medicine Overview of Varni 0.5mg Tablet
Introduction
Varni is a prescription medicine used to quit smoking by reducing the craving for a cigarette and the irritable feeling that occurs when you stop smoking. It works by blocking nicotine effect on the brain and this suppresses enjoyment while smoking or the urge to smoke. Varni may be taken with or without food, preferably at the same time each day. Take it in the dose and duration as advised by your doctor. If you have missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment. You should...
... Show moreUses of Varni
- Quitting smoking
Side effects of Varni
Common
- Nausea
- Headache
- Insomnia (difficulty in sleeping)
- Abnormal dreams
- Nasopharyngitis (inflammation of the throat and nasal passages)
How to use Varni
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Varni may be taken with or without food, but it is better to take it at a fixed time.
How Varni works
Varni is a smoking cessation aid. It works by mimicking the effect of nicotine by binding to the nicotine receptors in the brain. This reduces the urge to smoke, relieves withdrawal symptoms, and helps you quit smoking.
What if you forget to take Varni?
If you miss a dose of Varni, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Varni helps you to quit smoking by reducing the craving for a cigarette and the irritable feeling that occurs when you stop smoking.
- In addition, counselling should be done to increase the chances of a successful quit attempt.
- Quitting smoking can lower your chances of having lung disease, heart disease or getting certain types of cancer that are related to smoking.
- Varni can make you very sleepy. Don't drive or do anything requiring concentration until you know how it affects you.
- Stop taking Varni and inform your doctor if you notice sudden mood and behavior changes or develop suicidal thoughts.
- Inform your doctor if you have a history of heart diseases, fits (seizures), or other mental disorders.
Brief Description
Indication
Smoking cessation aid
Administration
Taken after eating with full glass of water
Adult Dose
Smoking Cessation Set a date to stop smoking and begin varenicline 1 week before this date Alternatively, the patient can begin varenicline and then quit smoking between days 8 and 35 of treatment Also see Administration Quit smoking date regimen Initiate regimen 1 week before quit smoking date Days 1-3: 0.5 mg PO qDay Days 4-7: 0.5 mg PO BID Day 8 to end of treatment: 1 mg PO BID If quitting is successful after 12 weeks, continue another 12 weeks at 1 mg q12hr Gradual approach to quitting For patients who are sure that they are not able or...
... Show moreChild Dose
<18 years: Safety and efficacy not established
Renal Dose
Renal impairment
Mild-to-moderate (CrCl ?30 mL/min): No dosage adjustment required
Severe (CrCl <30 mL/min): 0.5 mg PO qDay initially; may increase to 0.5 mg PO q12hr
ESRD on hemodialysis: Not to exceed 0.5 mg PO qDay
Contraindication
Documented hypersensitivity or skin reactions to drug or components of formulation. Nonsmokers.
Mode of Action
Varenicline Tartrate is a partial neuronal alpha 2 beta 2 nicotinic acetylcholine receptor agonist. It works as a smoking cessation aid by preventing nicotine stimulation of mesolimbic dopamine system. It also stimulates dopamine activity but to a much lesser extent than nicotine does, resulting in reduced craving and withdrawal symptoms.
Precaution
Monitor for signs of suicidal ideation or behaviour, or changes in behaviour. May affect performance of skilled tasks. Not recommended for use in children <18 yr. Pregnancy, lactation.
Side Effect
N>10%
Nausea (15-40%; dose related),Abnormal dreams,Headache,Insomnia
1-10%
Appetite changes,Chest pain,Constipation,Dry mouth,Dyspepsia,Dyspnea,Flatulence,Gastroesophageal reflux disease (GERD),Fatigue or lethargy,Pruritus,Rash,Somnolence,Rhinorrhea,Vomiting,Upper respiratory tract disorder
Frequency Not Defined (selected)
Abnormal liver function tests,Anemia,Anxiety,Arrhythmia,Arthralgia,Depression,Diarrhea,Dizziness,Epistaxis,Hypertension,Myocardial infarction (MI),Polyuria,Respiratory disorder
Interaction
Increased incidence of adverse effects (nausea, vomiting) w/ transdermal nicotine. Increased exposure w/ cimetidine.
ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন
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