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Xflam 400
Square Pharmaceuticals PLC.
Generic: Dexibuprofen
Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Xflam 400.
CONSULT YOUR DOCTOR
Xflam 400 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Xflam 400 is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
UNSAFE
Xflam 400 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CAUTION
Xflam 400 should be used with caution in patients with kidney disease. Dose adjustment of Xflam 400 may be needed. Please consult your doctor.
Regular monitoring of kidney function tests is advised in these patients while taking this medicine. Use of Xflam 400 is not recommended in severe kidney disease patients.
CAUTION
Xflam 400 should be used with caution in patients with liver disease. Dose adjustment of Xflam 400 may be needed. Please consult your doctor.
Use of Xflam 400 is not recommended in severe liver disease patients.
Medicine Overview of Xflam 400mg Tablet
Introduction
Xflam 400 is a pain relieving medicine. It is used for symptomatic treatment of pain and inflammation associated with osteoarthritis, pain during menstruation, and other muscular-skeletal or dental pain. Xflam 400 can be taken with food, preferably with a glass of water. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it. The most common side effects of this medicine include mild indigestion, diarrhea, nausea, vomiting, stomach pain,...
... Show moreUses of Xflam 400
- Pain relief
Side effects of Xflam 400
Common
- Vomiting
- Stomach pain
- Nausea
- Indigestion
- Heartburn
How to use Xflam 400
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xflam 400 is to be taken with food.
How Xflam 400 works
Xflam 400 is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).
Quick Tips
- You have been prescribed Xflam 400 to relieve pain and inflammation.
- Take it with food or milk to prevent upset stomach.
- Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
- Do not take indigestion remedies (antacids) within two hours of taking Xflam 400.
- Avoid consuming alcohol while taking Xflam 400 as it can increase your risk of stomach problems.
- Inform your doctor if you have a history of heart disease or stroke.
- Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.
Brief Description
Indication
Osteoarthritis, Pain, Fever, Pericarditis, Dysmenorrhea, Rheumatic disorders, Patent ductus arteriosus
Adult Dose
Oral
Pain and inflammation associated with musculoskeletal and joint disorders ; Dysmenorrhoea
Adult: 600-900 mg daily in 2-3 divided doses. May increase to 1200 mg daily for patients with acute conditions or exacerbations.
Max Dosage: 400 mg/dose and 1200 mg/day.
Hepatic impairment: Dose reduction is recommended.
Renal Dose
Renal impairment: Dose reduction is recommended.
Contraindication
Hypersensitivity to aspirin or NSAIDs; active or suspected GI ulcer or history of recurrent GI ulcer; GI bleeding or other active bleedings or bleeding disorders; active Crohn's disease or ulcerative colitis; haemorrhagic diasthesis and other coagulation disorders, or patients receiving anticoagulant therapy; severe heart failure, renal or hepatic impairment; child <18 yrs; pregnancy (third trimester).
Mode of Action
Dexibuprofen is a NSAID. It acts by inhibition of cyclo-oxygenase, which is involved in prostaglandin synthesis.
Precaution
History of bronchial asthma; renal or hepatic disorders; bleeding disorders; CV disease; elderly; lactation.
Side Effect
GI bleeding, heartburn, epigastric pain; dyspepsia, peptic ulcer; nausea, vomiting, diarrhoea; jaundice, hepatitis; rash; thrombocytopaenia; visual disturbances; tinnitus; depression; fatigue, headache, dizziness, vertigo.
Interaction
Avoid concomitant use with anticoagulants, other NSAIDs and salicylates. Increases risk of methotrexate and lithium toxicity.
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