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Locular
Square Pharmaceuticals PLC.
Generic: Brimonidine Tartrate (0.2 %, 0.15%) Eye prep
Safety Advices
বাংলা
English
SAFE IF PRESCRIBED
Locular is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Locular is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
To reduce the amount of Locular that reaches the breastmilk, place pressure over the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.
UNSAFE
Locular may cause side effects which could affect your ability to drive.
Locular may cause blurred or abnormal vision. This effect may seem worse at night or in reduced lighting and this may affect the ability to drive.
Medicine Overview of Locular 0.20% Eye Drop
Introduction
Locular is used in the treatment of ocular hypertension (pressure in the eye) and glaucoma. It helps to lower high pressure in the eye and reduces the risk of vision loss. This medicine may be used alone or in combination with another eye drop that reduces pressure in the eye. Locular is for external use only. Use it in the dose and duration as advised by the doctor. If you wear contact lenses, remove them before using the medication. Avoid touching the tip of the dropper to any surface as it may contaminate the eye drop. For best results, use...
... Show moreUses of Locular
- Ocular hypertension
- Glaucoma
Side effects of Locular
Common
- Erythema (skin redness)
- Foreign body sensation in eyes
- Blurred vision
- Dryness in mouth
- Dermatitis
- Burning sensation in eye
- Ocular hyperemia
- Stinging in the eyes
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Eye itching
- Allergic reaction in eye
How to use Locular
This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid.
How Locular works
Locular is a sympathomimetic. It works by decreasing the production of aqueous humour (fluid in the eye), thereby lowering the increased eye pressure.
What if you forget to take Locular?
If you miss a dose of Locular, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Locular helps lower high pressure in the eye and reduces the risk of vision loss.
- For best results, put one drop 2-3 times daily in the affected eye(s).
- Apply pressure on the corner of the eye (close to the nose) for about 1 minute, immediately after instilling the drop.
- Remove contact lenses before using Locular and allow at least 15 minutes before re-inserting them.
- Do not touch the tip of the dropper to any surface, or to your eye, to avoid contaminating the eye drops.
- Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
- It may cause short term blurring of vision when first used. Use caution before driving or using machines.
- It may cause temporary burning or itching sensation in the eye. Inform your doctor if this does not go away.
- Make sure to use within 4 weeks of opening the bottle.
Brief Description
Indication
Open-angle glaucoma, Ocular hypertension
Adult Dose
Ophthalmic
Open-angle glaucoma
Adult: Instill 1 drop of a solution bid-tid.
Child Dose
2 years: Instill 1 drop of a solution bid-tid.
Contraindication
This eye drops are contraindicated in patients with hypersensitivity to brimonidine tartrate or any component of this medication.This product is also contraindicated in patients receiving monoaminase oxidase inhibitor therapy.
Mode of Action
Brimonidine is an alpha 2-adrenoceptor agonist which works to reduce aqueous humor production and increase uveoscleral flow.
Precaution
General Brimonidine ophthalmic solution should be used with caution in patients with known hypersensitivity to other alpha-adrenoceptor agonists. Although brimonidine had minimal effect on blood pressure and heart rate of patients in clinical studies, caution should be exercised in treating patients with severe cardiovascular disease. Brimonidine has not been studied in patients with hepatic or renal impairment; caution should be exercised in treating such patients. Brimonidine should be used with caution in patients with depression, cerebral or coronary insufficiency. Lactation: It is not known whether this drug is excreted in milk. A decision should be made whether to discontinue nursing...
... Show moreSide Effect
Oral dryness,Conjunctival hyperemia,Allergic conjunctivitis,Eye pruritus,Rash,Photophobia,Headache,Fatigue,Dizziness,Dyspepsia,Blepharitis,Eye discharge
Pregnancy Category Note
Pregnancy Category: B
Lactation: It is not known whether this drug is excreted in milk. A decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
Interaction
Possibility of an additive or potentiating effect with CNS depressants e.g. alcohol, barbiturates, opiates, sedatives or anaesthetics. Caution when used with beta-blockers (ophthalmic and systemic), antihypertensives or cardiac glycosides. TCAs can affect the metabolism and uptake of circulating amines.
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