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Glophen
Globe Pharmaceuticals Ltd.
Generic: Chloramphenicol 0.5% Eye drops
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
Glophen may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Glophen is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
UNSAFE
Glophen may cause blurring of your vision for a short time just after its use. Do not drive until your vision is clear.
Medicine Overview of Glophen 0.50% Eye/Ear Drops
Introduction
Glophen is an antibiotic that fights bacteria. It is used to treat infections of the eye caused by bacteria. It works by killing the bacteria that cause these problems. Glophen helps to improve your symptoms and cure the underlying infection. Follow your doctor's instructions precisely for administering this medicine in the eye. It should be used regularly at evenly spaced time intervals as prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. It is effective...
... Show moreUses of Glophen
- Bacterial eye infections
Side effects of Glophen
Common
- Stinging in the eyes
- Blurred vision
How to use Glophen
This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid.
How Glophen works
Glophen is an antibiotic which stops the growth of bacteria that cause eye infections. It does so by preventing synthesis of essential proteins required by bacteria to carry out vital functions. This does not directly kill the bacteria, but prevents them from increasing in numbers, and eventually clears up the eye infection.
Quick Tips
- You have been prescribed Glophen for the treatment of bacterial infections of the eye.
- Do not skip any doses and finish the full course of treatment even if you feel better.
- Do not touch the tip to any surface, or to your eye, to avoid contamination.
- Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
- You should continue using the medicine for 48 hours after your symptoms have cleared up. However, do not use for longer than five days without consulting your doctor.
- It may cause short term blurring of vision when first used. Use caution before driving or using machines.
- Talk to your doctor if your symptoms haven't started to improve within two days of starting treatment, if they get worse during treatment, or if you get another eye infection.
- Do not wear contact lenses until your infection clears up.
- Throw away any medicine left at the end of the 5 day course.
Brief Description
Indication
Bacterial Conjunctivitis
Adult Dose
Ophthalmic
Ocular infections
Adult: Instill 1 drop every 2 hr. Increase dosage interval upon improvement. To continue treatment for at least 48 hr after complete healing.
Reduce dose once symptoms are controlled or apply a 1% ointment 3-4 times daily.
Hepatic impairment: Dose reduction may be required.
Renal Dose
Renal impairment: Dose reduction may be required.
Contraindication
History of hypersensitivity or toxic reaction to the drug; Herpes simplex and other virul conditions of the eye or ear, mycosis.
Mode of Action
Chloramphenicol inhibits bacterial protein synthesis by binding to 50s subunit of the bacterial ribosome, thus preventing peptide bond formation by peptidyl transferase. It has both bacteriostatic and bactericidal action against H. influenzae, N. meningitidis and S. pneumoniae.
Precaution
Avoid prolonged use. Discontinue immediately if local hypersensitivity reactions occur.
Side Effect
Ophthalmic application: Hypersensitivity reactions including rashes, fever and angioedema.
Interaction
Decreased effects of iron and vitamin B12 in anaemic patients. Phenobarbitone and rifampin reduce efficacy of chloramphenicol. Impairs the action of oral contraceptives.
Potentially Fatal: Increases the effect of oral anticoagulants, oral hypoglycaemic agents, phenytoin. Avoid concomitant administration with drugs that depress bone marrow function.
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