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Safety Advices
বাংলা
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UNSAFE
It is unsafe to consume alcohol with Curon.
CONSULT YOUR DOCTOR
Curon may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Curon is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
UNSAFE
Curon may cause side effects which could affect your ability to drive.
As Curon is given as part of a general anesthetic, you may feel tired, weak or dizzy for some time afterward and this affects your ability to drive.
SAFE IF PRESCRIBED
Curon is safe to use in patients with kidney disease. No dose adjustment of Curon is recommended.
However, inform your doctor if you have any underlying kidney disease.
CAUTION
Curon should be used with caution in patients with liver disease. Dose adjustment of Curon may be needed. Please consult your doctor.
Medicine Overview of Curon 10mg/ml Injection
Introduction
Curon belongs to a group of medicines called muscle relaxants. It is used along with general anesthesia or sedatives to provide skeletal muscle relaxation during surgical procedures. It is also used to facilitate emergency airway management in patients in intensive care. Curon is administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. The most common side effects of this medicine include injection site reactions such as pain, redness, and swelling. Long-term use of this medicine may...
... Show moreUses of Curon
- Skeletal mucle relaxation during surgery
Side effects of Curon
Common
- Skin rash
- Increased saliva production
- Injection site reactions (pain, swelling, redness)
- High blood pressure
How to use Curon
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Curon works
Curon relaxes the muscles by blocking the impulses from the nerves.
Quick Tips
- Curon is given as an injection by healthcare professionals only.
- It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how Curon affects you.
- You will be monitored continuously during the treatment to check the effect of the medicine.
- You will be given artificial ventilation until you are able to breathe on your own.
Brief Description
Indication
General anaesthesia, Skeletal muscle relaxation
Adult Dose
Intravenous
Muscle relaxant in general anaesthesia; Facilitate endotracheal intubation; Facilitate mechanical ventilation in intensive care
Adult: Initially, 80-100 mcg/kg by inj. Maintenance: 20-30 mcg/kg by inj or as continuous infusion at 0.8-1.4 mcg/kg/min.
Surgical procedures after intubation w/ suxamethonium: 30-50 mcg/kg.
Caesarean section: <100 mcg/kg.
Surgery under halothane and neurolept anaesth: Initially, 150-300 mcg/kg.
Child Dose
Intravenous
Muscle relaxant in general anaesthesia; Facilitate endotracheal intubation; Facilitate mechanical ventilation in intensive care
Child: 4 month: 80-100 mcg/kg by inj. Maintenance: 20-30 mcg/kg by inj or as continuous infusion at 0.8-1.4 mcg/kg/min.
Neonatal surgery: <100 mcg/kg.
Contraindication
Hypersensitivity to vecuronium or bromide.
Mode of Action
Vecuronium bromide inhibits depolarisation by blocking acetylcholine from binding to receptors on motor endplate.
Precaution
Patient w/ CV disease, oedema, neuromuscular disease, previous poliomyelitis, burn injury, severe electrolyte disturbances, altered blood pH, dehydration; obese patient. Hepatic and renal impairment. Childn. Pregnancy and lactation. Monitoring Parameters Monitor BP, heart rate; peripheral nerve stimulation.
Side Effect
Skeletal muscle weakness or paralysis, resp insufficiency or apnoea, bronchospasm, hypotension, tachycardia, acute urticaria, erythema, minimal induration, redness, itching, CV effects (e.g. changes in heart rate, cardiac index), myopathy.
Potentially Fatal: Anaphylaxis.
Interaction
Increases neuromuscular blockade with volatile anaesthetic agents (halothane, ether, enflurane, isoflurane, methoxyflurane, propofol and cyclopropane), fentanyl, other non-depolarising muscle relaxants, prior admin of succinylcholine, tetracyclines, polymyxins, diuretics, thiamine, MAOIs, bacitracin, colistin, sodium colistimethate, acylaminopenicillins, aminoglycoside antibiotics, high dose metronidazole, protamine, beta-adrenergic blocking agents, calcium antagonists e.g. verapamil, and Mg. Decreased neuromuscular blockade with anticholinesterases, prior chronic admin of corticosteroids, phenytoin, carbamazepine, noradrenaline, azathioprine, theophylline, calcium chloride.
