Introduction
Cutivate belongs to a group of medicines called steroids. It is used for treatment of skin conditions with inflammation and itching such as eczema, dermatitis, and psoriasis. It provide relief from pain, swelling, redness, and itching in several skin problems.
Cutivate is only meant for external use and should be used as advised by your doctor. You should normally wash and dry the affected area before applying a thin layer of the medicine. Avoid any contact with your eyes, nose, or mouth. Rinse it off with plenty of water in case of accidental contact. Avoid covering the treated area with airtight dressings such as bandages unless directed by a doctor.
Using of the medicine may cause itching or burning sensation, irritation, redness, and swelling at the site of application. These side effects are temporary and usually go away with time. However, if they persist or worsen, let your doctor know. Pregnant and breastfeeding mothers should consult their doctors before using this medicine. It should not be used in children below 1 year of age.
Uses of Cutivate
- Skin conditions with inflammation & itching
Side effects of Cutivate
Common
- Application site reactions (burning, irritation, itching and redness)
How to use Cutivate
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and gently massage the ointment.
How Cutivate works
Cutivate is a steroid medicine. It works by blocking the production of certain chemical messengers that make the skin red, swollen and itchy due to skin conditions such as atopic eczema, allergic contact dermatitis, and psoriasis.
Indication
Psoriasis, Eczema, Corticosteroid-responsive dermatoses
Adult Dose
Topical cream
Atopic Dermatitis, Corticosteroid-responsive Dermatoses
Apply a thin film to the affected skin areas once or twice daily.
Rub in gently. Reassess diagnosis if no improvements within 2 weeks
Child Dose
Topical cream
Atopic Dermatitis, Corticosteroid-responsive Dermatoses
Child > 3 months: Apply a thin film to the affected skin areas once or twice daily.
Contraindication
Hypersensitivity. Acne vulgaris, rosacea, perioral dermatitis, skin atrophy; hypersensitivity. Primary cutaneous viral infections (e.g. herpes simplex, chicken pox), perianal and genital pruritus, primary fungal or bacterial skin infections. Inhalation: Status asthmaticus.
Mode of Action
Fluticasone utilises a fluorocarbothioate ester linkage at the C17 position. It has potent vasoconstrictive and anti-inflammatory activity, but weak HPA inhibitory effect when applied topically.
Precaution
Children, pregnancy, lactation, concomitant skin infections. Concomitant skin/lung/systemic infections. Advised to rinse mouth with water every time after inhalation. Application to large areas, broken skin or under occlusive dressings.
Lactation: Excretion in milk unknown; use with caution
Side Effect
1-10%
Pruritus (2.9%),Dryness (1.2%),Skin irritation: (3%),Eczema (1%),Telangiectasia (2-5%),Numbness of fingers (1%)
<1%
Burning,Folliculitis,Acneiform lesions,Urticaria,Hypertrichosis,Lightheadedness,Viral,Warts,Impetigo,Skin infection
Frequency Not Defined
Striae,Pigmentation changes,HPA suppression (with higher potency used >2 wk),Erythema,Cushing syndrome,Sepsis,Hemorrhage reported,Edema/swelling
Potentially Fatal: Suppression of immune system.
Pregnancy Category Note
Pregnancy Category: C
Lactation: Excretion in milk unknown; use with caution
Interaction
May lead to increased plasma concentrations of fluticasone when used with CYP4503A4 inhibitors such as ritonavir.