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Chronic Disease Lab Promotion

Barbit

Injection-(200mg/ml)
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Incepta Pharmaceuticals Ltd.
5 Injections (1 Box)
৳ 72.72
৳ 80
9% OFF

Medicine Overview of Barbit 200mg/ml Injection

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Introduction

Barbit belongs to a class of medicines called barbiturates. It is a prescription medicine used to treat and prevent epilepsy (seizures). They also have hypnotic properties. Means, they slow down the activity of the brain and can make you feel sleepy or dizzy. Barbit may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor as it may be habit-forming with long-term use. If you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. Some common side effects of this medicine include nausea, diarrhea, hyperactivity, depression, confusion, decreased blood pressure and fatigue. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Remember to consult your doctor if you notice severe rashes, especially accompanied by fever after taking this medicine. It should be noted that long-term use of this medicine can cause pain in joints also.

Uses of Barbit

  • Epilepsy/Seizures

Side effects of Barbit

Common
  • Drowsiness
  • Nausea
  • Diarrhea
  • Hyperactivity
  • Depression
  • Confusion
  • Decreased blood pressure
  • Fatigue
  • Headache
  • Dizziness
  • Constipation
  • Excitement
  • Hangover

How to use Barbit

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Barbit may be taken with or without food, but it is better to take it at a fixed time.

How Barbit works

Barbit controls seizures or fits by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Quick Tips

  • Barbit helps in treatment and prevention of seizures.
  • It may be habit-forming with long-term use.
  • Talk with your doctor if it stops working well. Do not take more than prescribed.
  • It may make you very sleepy. Don't drive or do anything that requires mental focus until you know how it affects you.
  • Inform your doctor if you notice pain in your joints or if you have a history of bone disease.
  • Get regular blood tests done to monitor the amount of medication in your body.
  • Talk to your doctor immediately if you notice skin rash accompanied with fever.
  • Do not stop taking the medication suddenly without talking to your doctor.

Brief Description

Indication

Status epilepticus, Partial seizures, Sedation, Generalised tonic-clonic seizures, Hypnotic, Preoperative sedation

Administration

Reconstitution: Dilute w/ most IV infusion soln (e.g. NaCl 0.45% or 0.9%, lactated Ringer's, dextrose 5%, Ringer's). IV Administration Slow injection at <60 mg/min May be given IM into large muscle

Adult Dose

Parenteral Status epilepticus ; Emergency management of acute seizures Adult: As phenobarbital Na: 200-600 mg. OR 15-18 mg/kg IV loading dose infused at 25-60 mg/min; prepare to support ventilation; may repeat in 20-minute intervals PRN; not to exceed 30 mg/kg As a hypnotic Adult: 100-320 mg. Do not admin for >2 wk for the treatment of insomnia. Intramuscular Preoperative sedation Adult: As phenobarbital Na: 100-200 mg 60-90 min pre-op. Hepatic impairment: Reduce dose. Severe: Contraindicated.

Child Dose

Parenteral Status epilepticus ; Emergency management of acute seizures Child: As phenobarbital Na: 100-400 mg. OR Infants and children: 15-20 mg/kg IV infused at a rate not to exceed 2 mg/kg/min; not to exceed 1000 mg/dose <60 kg: IV rate at <30 mg/min May repeat with 5-10 mg/kg bolus dose after 15-30 min PRN; not to exceed cumulative dose of 40 mg/kg Seizures Neonates (<28 days): 3-5 mg/kg/day IV/PO in 1-2 divided doses Infants: 5-6 mg/kg/day in 1-2 divided doses 1-5 years: 6-8 mg/kg/day in 1-2 divided doses 6-12 years: 4-6 mg/kg/day in 1-2 divided doses >12 years: 1-3 mg/kg/day in 1-2 divided doses, OR 50-100 mg BID/TID Intramuscular Preoperative sedation Child: As phenobarbital Na: 16-100 mg 60-90 min pre-op. Intravenous Preoperative sedation Child: 1-3 mg/kg pre-op.

Renal Dose

Renal impairment: Reduce dose. Severe: Contraindicated.

Contraindication

Severe renal and hepatic disorders. Severe respiratory depression, dyspnoea or airway obstruction; porphyria. Pregnancy.

Mode of Action

Phenobarbitone is a short-acting barbiturate. It depresses the sensory cortex, reduces motor activity, changes cerebellar function, and produces drowsiness, sedation and hypnosis. Its anticonvulsant property is exhibited at high doses.

Precaution

Patient w/ history or sedative/hypnotic addiction; resp disease, depression or suicidal tendencies, hypoadrenalism. Avoid abrupt withdrawal. Mild to moderate renal and hepatic impairment. Elderly or debilitated patient, childn. Pregnancy and lactation. Patient Counselling May impair ability to drive or operate machinery. Monitoring Parameters Monitor CBC, LFTs, mental status and seizure activity. Lactation: Do not nurse

Side Effect

Common Ataxia,Dizziness,Drowsiness,Dysarthria,Fatigue,Headache,Irritability,Nystagmus,Paresthesia restlessness,Vertigo Geriatric patients: Excitement, confusion, depression Pediatric patients: Paradoxical excitement/hyperactivity Less Common Mental dullness,Constipation,Diarrhea,Nausea,Vomiting,Megaloblastic (folate-deficiency) anemia Uncommon Rash,Hypocalcemia,Hepatotoxicity Rare Stevens-Johnson syndrome,Rickets,Osteomalacia Potentially Fatal: Stevens-Johnson syndrome.

Interaction

May enhance the hepatotoxic potential of paracetemaol overdoses. May decrease levels/effects of various CYP isoenzyme substrates e.g. teniposide, methotrexate, antipsychotics, beta-blockers, calcium-channel blockers, other anticonvulsants, chloramphenicol, cimetidine, corticosteroids, ciclosporin, doxycycline, oestrogens, felbamate, griseofulvin, tacrolimus, furosemide, methadone, oral contraceptives, theophylline, TCAs, warfarin. May reduce effects of guanfacine. Reduced metabolism and or increased toxicity with chloramphenicol, felbamate, MAOIs, valproic acid. May enhance the nephrotoxic effects of methoxyflurane. Potentially Fatal: Additive sedation and/or respiratory depression with ethanol, sedatives, antidepressants, opioid analgesics, benzodiazepines and other CNS depressants. May decrease levels/effects of antiarrhythmic drugs e.g. disopyramide, propafenone, quinidine.

Buy Barbit from Arogga

In Bangladesh, you can get the original Barbit. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Barbit in Bangladesh?

The latest price of Barbit in Bangladesh is 72.72. You can buy Barbit at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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UNSAFE
It is unsafe to consume alcohol with Barbit.
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CONSULT YOUR DOCTOR
Barbit is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
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CONSULT YOUR DOCTOR
Barbit is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Monitor the baby for sleepiness, skin rash, and feeding issues.
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UNSAFE
Barbit may cause side effects which could affect your ability to drive.
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CAUTION
Barbit should be used with caution in patients with kidney disease. Dose adjustment of Barbit may be needed. Please consult your doctor. Use of Barbit is not recommended in patients with severe kidney disease.
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CAUTION
Barbit should be used with caution in patients with liver disease. Dose adjustment of Barbit may be needed. Please consult your doctor. Use of Barbit is not recommended in patients with severe liver disease.
Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.