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ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন

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Losium Plus 100

Name: Losium Plus 100 12.5mg+100mg Tablet
Brand: The Ibn Sina Pharmaceutical Ind. Ltd.
SKU: 23325
Price: 109.08 BDT
Availability: InStock
Rating: 4.9 (1 reviews)

Tablet - (12.5mg+100mg)

The Ibn Sina Pharmaceutical Ind. Ltd.

Generic: Hydrochlorothiazide + Losartan Potassium

Safety Advices

বাংলা

English

UNSAFE

It is unsafe to consume alcohol with Losium Plus 100.

CONSULT YOUR DOCTOR

Losium Plus 100 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

SAFE IF PRESCRIBED

Losium Plus 100 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

UNSAFE

Losium Plus 100 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

CAUTION

Losium Plus 100 should be used with caution in patients with severe kidney disease. Dose adjustment of Losium Plus 100 may be needed. Please consult your doctor. Use of Losium Plus 100 is not recommended in patients with severe kidney disease.

CAUTION

Losium Plus 100 should be used with caution in patients with liver disease. Dose adjustment of Losium Plus 100 may be needed. Please consult your doctor.

Medicine Overview of Losium Plus 100 12.5mg+100mg Tablet

Introduction

Losium Plus 100 is a combination of two medicines. It helps to control high blood pressure in different ways. If high blood pressure is not treated it can lead to heart attacks, strokes and kidney failure. You can take Losium Plus 100 with or without food. The dose will depend on your condition and how your respond to the medicine. Try to take it at the same time each day. It is important to keep taking this medicine until your doctor tells you not to. It contains a diuretic (water pill) and will make you urinate more so, it is...

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Uses of Losium Plus 100

Hypertension (high blood pressure)

Side effects of Losium Plus 100

Common

Nausea
Taste change
Upset stomach
Diarrhea
Headache
Dizziness
Weakness
Decreased blood pressure
Increased blood uric acid
Increased blood lipid level
Glucose intolerance
Electrolyte imbalance

How to use Losium Plus 100

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Losium Plus 100 may be taken with or without food, but it is better to take it at a fixed time.

How Losium Plus 100 works

Losium Plus 100 is a combination of two medicines: Losartan and Hydrochlorothiazide, which lowers the blood pressure effectively. Losartan is an angiotensin receptor blocker (ARB). It works by blocking the hormone angiotensin thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Hydrochlorothiazide is a diuretic that removes extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.

Quick Tips

You have been prescribed Losium Plus 100 for the treatment of high blood pressure.

It can be taken with or without food.

Losium Plus 100 may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, very dry mouth or muscle weakness.

It may cause dizziness. Get up slowly when rising from a sitting or lying position.

Use of Losium Plus 100 during pregnancy or breastfeeding is unsafe.

It may also decrease the risk of stroke and heart attacks.

Brief Description

Indication

Hypertension, Stroke, risk reduction of hypertensive or LVH patients

Adult Dose

Hypertension Initial: 50 mg/12.5 mg PO qDay If dose titrated upward, do not to exceed final titration of 100 mg/25 mg PO qDay or 50 mg/12.5 mg PO q12hr Decrease losartan to 25 mg PO qDay initially if volume depleted

Child Dose

Safety and efficacy not established

Renal Dose

Renal impairment CrCl 30 mL/min: No dosage adjustment required

Contraindication

Pregnancy, lactation; intravascular volume depletion.

Mode of Action

Hydrochlorothiazide increases renal excretion of sodium and chloride and reduces cardiac load. Losartan is an angiotensin II receptor (type AT1) antagonist antihypertensive which acts by blocking the actions of angiotensin II of renin-angiotensin-aldosterone system. The drug and its active metabolite selectively block the vasoconstrictor and aldosterone secreting effects of angiotensin II. The two drugs exert additive effects in hypertension.

Precaution

Existing electrolyte disturbances; hepatic cirrhosis; severe hepatic failure; oedema; elderly (>75 yr); renal impairment; hepatic impairment; diabetes, gout, hyperlipidaemia; hyperuricaemia; ECG: LVH and/or ventricular ectopics extrasystoles); volume depleted patients; patients on diuretics and salt restriction; renal artery stenosis; aortic and mitral stenosis. Monitor potassium concentration. Discontinue before performing tests for parathyroid function. Lactation: Discontinue drug or do not nurse

Side Effect

>10% Losartan Fatigue (14%),Hypoglycemia (14%),Chest pain (12%),Cough, incidence higher in previous cough related to ACE therapy (3-11%) 1-10% Losartan Diarrhea (2-10%),URI (8%),Hypotension (7%),Dizziness (4%),Nausea (2%) Hydrochlorothiazide Hypotension,Anorexia,Epigastric distress,Hypokalemia,Phototoxicity,Thrombocytopenia Potentially Fatal: Hypersensitivity reactions; hemolytic anaemia; toxic epidermal necrolysis.

Interaction

Reduced excretion of lithium; effect of diuretic, natriuretic & other antihypertensive w/ NSAIDs including selective COX-2 inhibitors. Do not co-administer w/ aliskiren in patients w/ diabetes & renal impairment. Losartan: Rifampin & fluconazole. Increased serum potassium w/ K-sparing diuretics (eg spironolactone, triamterene, amiloride), K supplements or salt substitutes containing K. Hydrochlorothiazide: Potentiate orthostatic hypotension w/ alcohol, barbiturates or narcotics. Antidiabetic drugs (oral agents, insulin), other antihypertensive drugs. Impaired absorption w/ cholestyramine & colestipol resins. Intensified electrolyte depletion w/ corticosteroids, ACTH, glycyrrhizin (liquorice). Possible decreased response to pressor amines (eg adrenaline); increased response to nondepolarizing skeletal muscle relaxants (eg tubocurarine). May...

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ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন

0 People recently viewed this

Losium Plus 100

Tablet - (12.5mg+100mg)

The Ibn Sina Pharmaceutical Ind. Ltd.

Generic: Hydrochlorothiazide + Losartan Potassium

Additional Offers

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৳50

For purchasing above ৳5000+

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৳20

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৳10

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

Losium Plus 100

Medicine Overview of Losium Plus 100 12.5mg+100mg Tablet

Losium Plus 100

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