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Leukeran

Tablet-(2mg)
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Rainbow Traders

Generic: Chlorambucil

25 Tablets (1 Box)
৳ 1033.53
৳ 1137
9% OFF

Medicine Overview of Leukeran 2mg Tablet

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Introduction

Leukeran is used in the treatment of some cancers of blood and lymphatic system. It may be also used to treat other kinds of cancer, as determined by the doctor. It is used alone or in combination with other cancer medicines. Leukeran should be taken empty stomach, or 1 hour before and 2 hours after a meal. But, try to have it at the same time every day for most benefits. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include anemia (low number of red blood cells), decreased blood cells (red cells, white cells, and platelets) decreased white blood cell count, infection, nausea and vomiting. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Inform your doctor if you have a medical history, of bleeding disorders, heart or liver disease, radiation treatment or any infection. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Leukeran

  • Blood cancer
  • Hodgkin’s disease

Side effects of Leukeran

Common
  • Anemia (low number of red blood cells)
  • Decreased blood cells (red cells, white cells, and platelets)
  • Decreased white blood cell count (neutrophils)
  • Decreased white blood cell count
  • Bone marrow suppression
  • Nausea
  • Vomiting
  • Diarrhea
  • Mouth ulcer

How to use Leukeran

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Leukeran is to be taken empty stomach.

How Leukeran works

Leukeran is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

What if you forget to take Leukeran?

If you miss a dose of Leukeran, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick Tips

  • Leukeran should be taken one hour before a meal or two hours after a meal.

Brief Description

Indication

Lymphocytic leukemia, non-Hodgkin lymphoma, Waldenstrm macroglobulinemia, polycythemia vera, trophoblastic neoplasms, ovarian carcinoma, nephrotic syndrome, Hodgkin's disease

Administration

Should be taken on an empty stomach. Take on an empty stomach. Ensure adequate hydration. Swallow whole, do not chew/crush.

Adult Dose

Chronic Lymphatic (Lymphocytic) Leukemia 0.1 mg/kg/day for 3-6 weeks or 0.4 mg/kg (increased by 0.1 mg/kg/dose until response/toxicity observed) biweekly or 0.4 mg/kg (increased by 0.1 mg/kg/dose until response observed) monthly or 0.03-0.1 mg/kg/day continuously Reduce initial dose if administered within 4 weeks after a full course of radiation/myelosuppressive therapy or patients with bone marrow disease Not to exceed 0.1 mg/kg/day if bone marrow infiltrated with lymphocytes Hodgkin's Lymphoma 0.2 mg/kg/day for 3-6 weeks or 0.4 mg/kg (increased by 0.1 mg/kg/dose until response/toxicity observed) biweekly or 0.4 mg/kg (increased by 0.1 mg/kg/dose until response or toxicity observed) monthly or 0.03-0.1 mg/kg/day continuously Reduce initial dose if administered within 4 weeks after a full course of radiation/myelosuppressive therapy or patients with bone marrow disease Not to exceed 0.1 mg/kg/day if bone marrow infiltrated with lymphocytes Hepatic Impairment Primarily metabolized in liver; dose reduction may be required

Renal Dose

Renal Impairment <1% (including metabolites) excreted in urine; no dose adjustment required

Contraindication

Hypersensitivity. Pregnancy and lactation. Porphyria.

Mode of Action

Chlorambucil interferes with DNA replication and RNA transcription by alkylation and cross-linking cellular DNA strands, thus leading to disruption of the nucleic acid function.

Precaution

Renal or hepatic dysfunction. Perform blood counts regularly. Seizure disorder, bone marrow suppression. Patient who has received radiation therapy, myelosuppressive drugs or has a depressed baseline leukocyte/platelet count within the previous 4 wk. Increased incidence of acute leukaemias and other secondary malignancies. Lactation: not known if excreted in breast milk; do not nurse

Side Effect

>10% Neutropenia (25-33%),Anemia,Leukopenia,Thrombocytopenia Frequency Not Defined Seizures,Hallucinations,Peripheral neuropathy,Nausea,Vomiting,Pulmonary fibrosis,GI effects,Leukemia,Myelosuppression,Hyperuricemia,Infertility,Hepatotoxicity & jaundice,Type I hypersensitivity,Rash,Stevens-Johnson syndrome (rare),Toxic epidermal necrosis (rare),Urticaria,Erythema multiforme (rare),Secondary malignancies Potentially Fatal: Severe bone marrow suppression, carcinogenic and human infertility.

Pregnancy Category Note

Pregnancy Category: D Lactation: not known if excreted in breast milk; do not nurse

Interaction

Impairs immune response to vaccines, possible infection after admin of live vaccines.

Buy Leukeran from Arogga

In Bangladesh, you can get the original Leukeran. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Leukeran in Bangladesh?

The latest price of Leukeran in Bangladesh is 1033.53৳. You can buy Leukeran at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Leukeran. Please consult your doctor.
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CONSULT YOUR DOCTOR
Leukeran may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
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UNSAFE
Leukeran is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
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CONSULT YOUR DOCTOR
It is not known whether Leukeran alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
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CAUTION
Leukeran should be used with caution in patients with kidney disease. Dose adjustment of Leukeran may be needed. Please consult your doctor. Careful monitoring by a doctor is important as kidney disease patients are at an increased risk of bone marrow depression and inflammation and infections of urinary bladder while taking this medicine.
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CONSULT YOUR DOCTOR
There is limited information available on the use of Leukeran in patients with liver disease. Please consult your doctor.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.