>10%
Neutropenia (25-33%),Anemia,Leukopenia,Thrombocytopenia
Frequency Not Defined
Seizures,Hallucinations,Peripheral neuropathy,Nausea,Vomiting,Pulmonary fibrosis,GI effects,Leukemia,Myelosuppression,Hyperuricemia,Infertility,Hepatotoxicity & jaundice,Type I hypersensitivity,Rash,Stevens-Johnson syndrome (rare),Toxic epidermal necrosis (rare),Urticaria,Erythema multiforme (rare),Secondary malignancies
Potentially Fatal: Severe bone marrow suppression, carcinogenic and human infertility.