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Acaril 50
The White Horse Pharmaceuticals Ltd
Generic: Acarbose
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
Acaril 50 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor
CONSULT YOUR DOCTOR
Caution is advised when consuming alcohol with Acaril 50. Please consult your doctor.
CONSULT YOUR DOCTOR
Information regarding the use of Acaril 50 during breastfeeding is not available. Please consult your doctor.
SAFE
Acaril 50 does not usually affect your ability to drive.
CAUTION
Acaril 50 should be used with caution in patients with kidney disease. Dose adjustment of Acaril 50 may be needed. Please consult your doctor. Use of Acaril 50 is not recommended in patients with severe kidney disease.
CAUTION
Acaril 50 should be used with caution in patients with liver disease. Dose adjustment of Acaril 50 may be needed. Please consult your doctor. Use of Acaril 50 is not recommended in patients with severe liver disease.
Medicine Overview of Acaril 50mg Tablet
Introduction
Acaril 50 is used to treat people with type 2 diabetes mellitus. It helps lower the blood sugar levels after meals. It belongs to a group of medicines known as alpha-glucosidase inhibitors. This medicine is usually prescribed in combination with other diabetes medications. Acaril 50 should be taken just before a meal or along with the first mouthful of food. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your blood sugar levels. It may be increased gradually. Do not stop taking it without consulting your...
... Show moreUses of Acaril 50
- Type 2 diabetes mellitus
Side effects of Acaril 50
Common
- Flatulence
- Abdominal pain
- Diarrhea
How to use Acaril 50
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it
Acaril 50 is to be taken with food.
How Acaril 50 works
Acaril 50 is an anti-diabetic medicine. It inhibits the intestinal enzymes responsible for breaking complex sugars into simple sugars such as glucose. This prevents blood glucose levels from rising very high immediately after meals.
What if you forget to take Acaril 50?
If you miss a dose of Acaril 50, skip it and continue with your normal schedule. Do not double the dose.
Quick Tips
- Acaril 50 is used together with other diabetes medicines to control blood sugar and avoid long-term complications.
- You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Acaril 50.
- Acaril 50 lowers your post-meal blood sugar levels. Therefore, it should be taken before meals.
- Side effects such as stomach pain, gas, and diarrhea may occur during the first few weeks of treatment but should get better with time.
Brief Description
Indication
Dosage Adult: PO Initial: 25 mg/day q8hr. May adjust gradually. Maintenance: 50-100 mg 3 times/day. Max: <60 kg: 50 mg 3 times/day. >60 kg: 100 mg 3 times/day. Hepatic Impairment Severe
Administration
May enhance effects of other antidiabetics including insulin. Diminished effects w/ GI adsorbents (e.g. charcoal) and digestive enzyme preparations containing carbohydrate splitting enzymes (e.g. amylase, pancreatin). Neomycin and colestyramine may enhance effects of acarbose. May inhibit absorption of digoxin.
Adult Dose
Monitor LFT every 3 mth for 1st yr and periodically thereafter especially for doses >50 mg tid. Reduce dose or withdraw therapy if transaminases elevations persist. If hypoglycaemia occurs, give glucose orally as a 1st aid measure. Adhere strictly to the prescribed diabetic diet to avoid intensification of GI symptoms. Lactation: not known if crosses into breast milk, avoid using in nursing women.
Renal Dose
Acarbose competitively and reversibly inhibits pancreatic alpha-amylase and intestinal brush border alpha-glucosidases, resulting in retardation of glucose absorption from hydrolysed complex carbohydrates and reduction of blood-glucose concentrations.
Mode of Action
Should be taken with food. Take w/ 1st bite of each main meal.
Precaution
Type 2 DM
Side Effect
Renal Impairment CrCl Dosage <25 Contraindicated.
Pregnancy Category Note
>10% abdominal pain (19%),diarrhea (31%),elevated serum transaminases, flatulence (74%) Potentially Fatal: Hepatotoxicity.
Interaction
Patients <18 yr; diabetic ketoacidosis or cirrhosis; malabsorption; inflammatory bowel disease; with or pre-disposed to intestinal obstruction; intestinal diseases that affect digestion or absorption; conditions that worsen as a result of increased gas formation e.g. hernias; colonic ulcers; hepatic impairment; CrClr< 25 ml/min/1.73m2. Pregnancy, lactation.
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