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Mexlo
Square Pharmaceuticals PLC.
Generic: Lomefloxacin 0.3% Eye or Ear prep
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
Mexlo may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Mexlo is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
SAFE
Mexlo does not usually affect your ability to drive.
Medicine Overview of Mexlo 0.30% Eye/Ear Drops
Introduction
Mexlo is an antibiotic, used in the treatment of bacterial infections of the eye. It relieves the symptoms of the infection by stopping the further growth of the causative microorganisms. Mexlo is for external use only. Take it in the dose and duration as advised by your doctor. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid. Avoid skipping any doses and finish the full course of treatment even if you feel better. It may cause burning sensation in the eyes immediately following...
... Show moreUses of Mexlo
- Bacterial eye infections
Side effects of Mexlo
Common
- Burning sensation in eye
How to use Mexlo
This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid.
How Mexlo works
Mexlo is an antibiotic. It treats bacterial eye infections by preventing the bacteria from dividing and repairing. It does so stopping the action of a bacterial enzyme called DNA-gyrase.
What if you forget to take Mexlo?
If you miss a dose of Mexlo, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- You have been prescribed Mexlo for the treatment of bacterial infections of the eye.
- Do not skip any doses and finish the full course of treatment even if you feel better.
- Apply pressure on the corner of the eye (close to the nose) for about 1 minute, immediately after instilling the medication.
- Do not touch the tip to any surface, or to your eye, to avoid contamination.
- Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
- It may cause short term blurring of vision when first used. Use caution before driving or using machines.
- Do not wear contact lenses until your infection clears up.
- Make sure to use within 4 weeks of opening the medication.
Brief Description
Indication
Otitis media, Bacterial Conjunctivitis, Otitis externa
Adult Dose
Ophthalmic
Bacterial conjunctivitis
Adults
At the beginning of therapy on day 1: Instill 5 drops into the conjunctival sac within 20 minutes.
Thereafter, until day 7-9: Instill 1 drop 3 times daily into the conjunctival sac.
Otic/Aural
Otitis externa
10 drops (0.5 mL, 1.5 mg ofloxacin) instilled into the affected ear once daily for 7 days.
Chronic Suppurative Otitis Media with perforated tympanic membranes:
10 drops (0.5 mL, 1.5 mg ofloxacin) instilled into the affected ear twice daily for 14 days.
Child Dose
Ophthalmic Bacterial conjunctivitis Adults At the beginning of therapy on day 1: Instill 5 drops into the conjunctival sac within 20 minutes. Thereafter, until day 7-9: Instill 1 drop 3 times daily into the conjunctival sac. Otic/Aural Otitis externa For patients 13 years and older: 10 drops (0.5 mL, 1.5 mg ofloxacin) instilled into the affected ear once daily for 7 days. Acute Otitis Media (1 to 12 years old) with tympanostomy tubes is: 5 drops (0.25 mL, 0.75 mg ofloxacin) instilled into the affected ear twice daily for 10 days. Chronic Suppurative Otitis Media with perforated tympanic membranes: 12...
... Show moreContraindication
Lomefloxacin is contraindicated in patients with a history of hypersensitivity to Lomefloxacin, quinolone or any other components of this product.
Mode of Action
Lomefloxacin promotes breakage of double-stranded DNA in susceptible organisms and inhibits DNA gyrase, which is essential in reproduction of bacterial DNA.
Precaution
Long term treatment with antibiotics may enhance development of secondary fungal infections or may support growth of non-susceptible bacteria. Contact lenses should not be worn in the presence of infectious eye diseases and the product should not be instilled while wearing contact lenses. During prolonged use, it is recommended that physicians conduct periodic examinations of the eye, including measurement of the intraocular pressure.
Side Effect
Mild, transient sensation of burning, irritation or pain may be experienced on instillation.
Interaction
Reduced bioavailability with sucralfate, antacids containing magnesium or aluminium, vitamin or mineral supplements containing iron. Increased serum levels with cimetidine. Potential increase in serum levels of ciclosporin. Renal elimination reduced with probenecid.
Potentially Fatal: Increased risk of ventricular arrhythmias with class IA (quinidine, procainamide) or class III (amiodarone, sotalol) antiarrhythmic agents.
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