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Hypnoclone
Popular Pharmaceuticals Ltd.
Generic: Zopiclone
Safety Advices
বাংলা
English
UNSAFE
Hypnoclone may cause excessive drowsiness with alcohol.
CONSULT YOUR DOCTOR
Hypnoclone is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
CONSULT YOUR DOCTOR
Hypnoclone is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
UNSAFE
Hypnoclone may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CAUTION
Hypnoclone should be used with caution in patients with kidney disease. Dose adjustment of Hypnoclone may be needed. Please consult your doctor.
CAUTION
Hypnoclone should be used with caution in patients with liver disease. Dose adjustment of Hypnoclone may be needed. Please consult your doctor.
Use of Hypnoclone is not recommended in patients with severe liver disease.
Medicine Overview of Hypnoclone 7.5mg Tablet
Introduction
Hypnoclone is a prescription medicine used for short term treatment of insomnia. It reduces sleep onset time and frequent awakening at night. This medicine improves sleep maintenance and therefore ensures sound sleep. Hypnoclone is never used for long term treatment of insomnia, because of its high habit forming potential. It should be taken on an empty stomach, preferably just before going to bed. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by...
... Show moreUses of Hypnoclone
- Insomnia
Side effects of Hypnoclone
Common
- Metallic taste
How to use Hypnoclone
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Hypnoclone is to be taken empty stomach.
How Hypnoclone works
Hypnoclone is a nonbenzodiazepine hypnotic. It has hypnotic and anxiolytic properties. It works by regulating the GABA receptor, thus relaxes the nerves and brain. This is how it helps you to fall asleep.
What if you forget to take Hypnoclone?
If you miss a dose of Hypnoclone, skip it and continue with your normal schedule. Do not double the dose.
Quick Tips
- Your doctor has prescribed Hypnoclone to help you fall asleep faster and sleep for longer.
- It is best taken without food as a high-fat meal can reduce its absorption and effect.
- Take it 30 to 45 minutes before bedtime and only when you have time to sleep for at least 7 hours.
- It makes you feel dizzy next morning. Don't drive or do anything requiring concentration until you know how it affects you.
- It does not affect total sleep time. However, it reduces sleep onset time and frequent awakening at night.
- Never share your medication with any other person who also has a sleep problem.
- It may cause a bitter taste in your mouth or a dry mouth. Try sipping water and inform your doctor if it bothers you.
- Inform your doctor if your sleep doesn’t improve after 7 to 10 days of treatment.
- Stop taking medication and inform your doctor If you experience sleep driving or memory loss.
- Do not stop taking medication suddenly as it may lead to anxiety, mood changes, and restlessness.
Brief Description
Indication
Insomnia
Administration
May be taken with or without food.
Adult Dose
Oral
Short-term management of insomnia
Adult: 7.5 mg at bedtime.
Elderly: Initially, 3.75 mg at bedtime.
Hepatic impairment: Mild to moderate: Initially 3.75 mg at bedtime. Severe: Contraindicated.
Child Dose
Child: Not recommended.
Renal Dose
Renal impairment: Initiate at 3.75 mg at bedtime.
Contraindication
Myasthenia gravis; respiratory failure; severe sleep apnoea syndrome; severe hepatic impairment; pregnancy, lactation.
Mode of Action
Zopiclone is a cyclopyrrolone derivative with hypnotic and sedative actions, anticonvulsant and muscle relaxant properties similar to benzodiazepines. It binds to a site in the GABA-A-benzodiazepine-chloride channel macromolecular-receptor complex which is different from that of the benzodiazepine binding site.
Precaution
Hepatic and renal insufficiency; elderly; psychiatric disorders; history of drug abuse. May impair ability to drive or operate machinery. Limit treatment duration to <4 wk to minimise risk of dependence and tolerance. Avoid abrupt discontinuation of therapy.
Side Effect
Metallic or bitter aftertaste; irritability, confusion, depressed mood, aggressiveness, incoordination, anterograde amnesia, mild increase in LFTs, drowsiness, lightheadedness, nausea, vomiting, urticaria, rashes.
Interaction
Reduced hypnotic effect with phenytoin and carbamazepine. Increased drowsiness and incoordination with TCAs. Increased CNS depressant effect with alcohol and other CNS depressants. Decreased zopiclone concentration with rifampicin. Possible increase in zopiclone concentration with CYP3A4 inhibitors e.g. erythromycin, clarithromycin, ketoconazole, itraconazole, ritonavir.
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