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Konakion
Roche Bangladesh Pharmaceutical
Generic: Phytomenadione (Vitamin K1)
Safety Advices
বাংলা
English
CAUTION
Caution is advised when consuming alcohol with Konakion. Please consult your doctor.
CONSULT YOUR DOCTOR
Konakion may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Konakion is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
SAFE
Konakion does not usually affect your ability to drive.
SAFE IF PRESCRIBED
Konakion is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Konakion may not be needed in these patients. Please consult your doctor.
SAFE IF PRESCRIBED
Konakion is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Konakion may not be needed in these patients. Please consult your doctor.
Medicine Overview of Konakion 2mg/0.2ml Injection
Introduction
Konakion is a medicine used to treat vitamin K deficiency in the body. It helps in improving conditions caused due to low levels of vitamin K in the body. Vitamin K is an important nutrient which is necessary for blood clotting and bone metabolism. Konakion is given under the supervision of a healthcare professional and should not be self-administered. You should take it regularly to get the most benefit from it. This medicine may be only part of a complete program of treatment that also includes making changes to your diet and taking vitamin supplements. Konakion is generally safe with...
... Show moreUses of Konakion
- Nutritional deficiencies
Side effects of Konakion
Common
- No common side effects seen
How to use Konakion
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Konakion works
Konakion is a synthetic form of vitamin K. It restores the activity of vitamin K and speeds up the normal blood clotting process to prevent or treat bleeding caused due to too high dose of warfarin.
Quick Tips
- Do not use phytomenadione if you have glucose-6-phosphate dehydrogenase (G6PD) deficiency (disorder in which the red blood cells are destroyed faster leading to anemia).
- Do not use it as antidote for heparin.
Brief Description
Indication
Vitamin K deficiency, Over-anticoagulation, Vitamin K deficiency bleeding
Administration
May be taken with or without food.
Adult Dose
Oral
Vitamin K deficiency due to drugs or malabsorption
Adult: 10-40 mg daily.
Over-anticoagulation
Adult: Up to 5 mg may be used. Dose depends on INR and degree of haemorrhage.
Intravenous
Over-anticoagulation
Adult: 0.5-5 mg via slow IV inj. Dose depends on INR and degree of haemorrhage.
Child Dose
Intramuscular
Prophylaxis of vitamin K deficiency bleeding in neonates
Child: Neonate: 0.5-1 mg, given as a single dose via IM inj.
Alternatively, 2 mg may be given orally, followed by a 2nd dose of 2 mg after 4-7 days.
Parenteral
Vitamin K deficiency bleeding in neonates
Child: Infant: 1 mg by IV/IM/SC inj, further doses may be given if necessary
Contraindication
Hypersensitivity.
Mode of Action
Phytomenadione promotes hepatic synthesis of clotting factors. It is a naturally occurring compound that is used to prevent and treat haemorrhages related to vitamin K deficiency.
Precaution
Increased risk of severe haemolytic anaemia in neonates after large doses; severe hepatic impairment; pregnancy. Premature neonates weighing <2.5 kg.
Lactation: Excreted in breast milk; use caution
Side Effect
Anaphylaxis, dyspnoea, cyanosis, pain, swelling, phloebitis at the Inj site, diaphoresis, dizziness, hypotension (rare), allergic reactions after SC and IM inj.
Interaction
Decreased effect of oral anticoagulants.
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