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Tericin

Injection-(50mg/vial)
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Beacon Pharmaceuticals PLC

Generic: Amphotericin B

1 Injection
৳ 13675.91
৳ 15045
9% OFF

Medicine Overview of Tericin 50mg/vial Injection

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Introduction

Tericin is an antifungal medication. It is used in the treatment of severe fungal infections and kala-azar. It kills the infection causing fungi and thus, treats the infection. Tericin is administered as an injection by a healthcare professional. Kindly do not self administer. Before you take this medicine, inform your doctor if you suffer from diabetes, liver/kidney problems or are on dialysis or have low potassium level in blood. It may lead to a few common side effects like headache, vomiting, nausea, stomach cramps and fever. You may also notice some injection site reactions like pain, swelling or redness. Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding.

Uses of Tericin

  • Severe fungal infections
  • Kala-azar

Side effects of Tericin

Common
  • Headache
  • Vomiting
  • Nausea
  • Stomach cramp
  • Fever
  • Anemia (low number of red blood cells)
  • Heartburn
  • Hyperventilation (rapid breathing)

How to use Tericin

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Tericin works

Tericin is an antifungal medication. It kills fungi by destroying the fungal cell membrane.

What if you forget to take Tericin?

If you miss a dose of Tericin, please consult your doctor.

Quick Tips

  • It is usually given as an injection over 1-2 hours under the supervision of a medical professional.
  • Tericin can cause rash, chills, headache, and tiredness during initial days of the treatment, but these may fade away with time.
  • Your doctor may ask you for regular blood tests to monitor your blood sugar, potassium, magnesium and kidney function.
  • Inform your doctor immediately if you notice pain or blood upon urination, swelling of the face and trouble breathing.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Brief Description

Indication

Adult: Dosing regimens are applicable to amphotericin B (conventional). PO Oral candidiasis Per loz contains amphotericin B 10 mg: Suck 1 loz 4 times/day, up to 8 loz/day if needed. IV Systemic Fungal Infections Test dose: 1 mg IV x1 infused over 20-30 min Load: 0.25-0.5 mg/kg IV infused over 2-6 hr Maintenance: 0.25-1 mg/kg IV qDay OR up to 1.5 mg/kg IV qOD (may increase gradually by 0.25 mg-increments/day)

Administration

Increased toxicity with flucytosine. Drug induced renal toxicity enhanced in presence of other nephrotoxic medications. Antagonises effects of azole antifungals. Potentially Fatal: Potentiates K loss by corticosteroids. Avoid diuretics. Enhances digitalis toxicity and neuromuscular blocker effects.

Adult Dose

Renal and hepatic impairment; pregnancy; monitor renal and liver function changes. Lactation: Excretion in milk is unknown; due to the potential for serious adverse reactions in breast-fed infants, a decision should be made whether to discontinue nursing or whether to discontinue the drug, taking into account the importance of the drug to the mother

Renal Dose

Amphotericin B is a polyene antifungal antibiotic which alters cell membrane permeability by binding to ergosterol, thus causing leakage of cell components and subsequent cell death. It is active against Absidia spp, Aspergillus spp, Basidiobolus spp, B. dermatitidis, Candida spp, C. immitis, Conidobolus spp, C. neoformans, H. capsulatum, Mucor spp, P. brasiliensis, Rhizopus spp, Rodotorula spp. and S. schenckii.

Contraindication

Systemic Fungal Infections Test dose: 0.1 mg/kg IV, not to exceed 1 mg; administer over 20-60 min Initial dose: 0.25 mg/kg/dose IV qDay/qOD Maintenance: Increase by 0.25 mg/day increments as tolerated to 1-1.5 mg/kg/day

Mode of Action

IV Administration Use promptly after dilution. Infuse over 2-6 hr Reconstitution: For conventional amphotericin B: Reconstitute with sterile water for inj (without preservatives), then further dilute with glucose inj 5% (with a pH>4.2) to a final concentration not exceeding 0.1 mg/ml for peripheral infusion or 0.25 mg/ml for central infusion.

Precaution

Endocarditis, Systemic fungal infections, Visceral leishmaniasis, Primary amoebic meningoencephalitis, Thrush, Cryptococcal meningitis, Candidiasis, Aspergillosis, Candidal cystitis

Side Effect

Renal Impairment CrCl <10 mL/min: 0.5-0.7 mg/kg IV q24-48hr Consider other antifungal agents that may be less nephrotoxic Intermittent hemodialysis: 0.5-1 mg/kg IV q24hr after dialysis session Continuous renal replacement therapy: 0.5-1 mg/kg IV q24hr

Pregnancy Category Note

>10% Anorexia,Chills,Diarrhea,Fever,Headache,Hypokalemia,Hypomagnesemia,Hypotension,Malaise,Nausea,Pain (generalized),Pain at injection site,Renal function abnormalities,Tachypnea,Vomiting 1-10% Arachnoiditis,Delerium,Flushing,Hypertension,Leukocytosis,Lumbar nerve pain,Paresthesia,Urinary retention <1% Agranulocytosis,Anuria,Bone marrow suppression,Cardiac arrest,Coagulation defects,Convulsions,Dyspnea,Hearing loss,Leukopenia,Maculopapular rash,Renal failure,Thrombocytopenia,Vision changes Potentially Fatal: Anaphylactic reaction; leucoencephalopathy. Overdosage can result in cardio-respiratory arrest.

Interaction

Hypersensitivity; lactation; do not give to patients receiving antineoplastics.

Buy Tericin from Arogga

In Bangladesh, you can get the original Tericin. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Tericin in Bangladesh?

The latest price of Tericin in Bangladesh is 13675.91৳. You can buy Tericin at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Tericin. Please consult your doctor.
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SAFE IF PRESCRIBED
Tericin is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
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CONSULT YOUR DOCTOR
Tericin is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
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UNSAFE
Tericin may cause side effects which could affect your ability to drive.
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SAFE IF PRESCRIBED
Tericin is safe to use in patients with kidney disease. No dose adjustment of Tericin is recommended. However, inform your doctor if you have any underlying kidney disease.
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CONSULT YOUR DOCTOR
There is limited information available on the use of Tericin in patients with liver disease. Please consult your doctor.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.