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Linexil IV Infusion

Solution-(0.20%)
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Opsonin Pharma Limited

Generic: Linezolid 0.2% Inj

1 x 300ml bot
৳ 410.28
৳ 451.36
9% OFF

Medicine Overview of Linexil IV Infusion 0.20% Solution

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Introduction

Linexil IV Infusion is an antibiotic medicine used in the treatment of severe bacterial infections. It is used to treat infections of lungs (Pneumonia), skin and soft tissues. Linexil IV Infusion may be taken with or without food, preferably at a fixed time. You should take it regularly as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. Do not stop taking it until you have finished the complete course, even when you feel better. If you stop taking this medicine too early then infection may return or worsen. The most common side effects of Linexil IV Infusion include vomiting, headache, nausea, decreased blood cell counts and diarrhea. These are usually mild but let your doctor know if they bother you or last more than a few days. Before using it, you should tell your doctor if you are allergic to any antibiotics or have any kidney or liver problems. You should also let your doctor know all other medicines you are taking as they may affect, or be affected by this medicine. Pregnant and breastfeeding mothers should consult their doctor before using it.

Uses of Linexil IV Infusion

  • Severe bacterial infections

Side effects of Linexil IV Infusion

Common
  • Vomiting
  • Headache
  • Nausea
  • Decreased blood cells (red cells, white cells, and platelets)
  • Diarrhea

How to use Linexil IV Infusion

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Linexil IV Infusion may be taken with or without food, but it is better to take it at a fixed time. Avoid Linexil IV Infusion with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Linexil IV Infusion works

Linexil IV Infusion is an antibiotic. It stops bacterial growth by preventing synthesis of essential proteins required by bacteria to carry out vital functions.

Quick Tips

  • Linexil IV Infusion treats serious infections caused by certain types of bacteria.
  • Take it with food to avoid an upset stomach.
  • Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
  • Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
  • Avoid taking excessive cheese, processed meats, alcohol, or soy sauce while taking this medication as these may cause an excessive rise in your blood pressure.
  • Inform your doctor if you develop fever, shortness of breath, or any changes in your vision.
  • Do not take it for more than 14 days without consulting your doctor.

Brief Description

Indication

Community-acquired pneumonia, Skin and skin structure infections, Nosocomial pneumonia

Administration

Patients who commence treatment on the parenteral formulation may be switched to either oral presentation when clinically indicated. In such circumstances, no dose adjustment is required as Linzolid (Linezolid) has an oral bioavailability of approximately 100%. The injection should be administered over a period of 30 to 120 minutes.

Adult Dose

Intravenous Vancomycin-resistant Enterococcus faecium Adult: 600 mg 12 hrly for 14-28 days. Methicillin-resistant Staphylococcus aureus infections Adult: 600 mg bid for 7-21 days. Community-acquired pneumonia; Nosocomial pneumonia; Complicated skin and skin structure infections Adult: 600 mg 12 hrly for 10-14 days. Elderly: No dosage adjustment needed. Hepatic impairment: Mild to moderate: No dosage adjustment needed.

Child Dose

Intravenous For Pediatric Patients Pneumonia, complicated skin infections, vancomycin resistant enterococci: Birth–11 y: 30 mg/kg/day q8h >11 y: 1,200 mg/day q12h Uncomplicated skin infections: Birth–5 y: 30 mg/kg/day q8h 5–11 y: 20 mg/kg/day q12h >11–18 y: 1,200 mg/day q12h

Contraindication

Linzolid formulations are contraindicated for use in patients who have known hypersensitivity to Linzolid or any of the other product components. Linzolid should not be used in patients taking any medicinal product which inhibits monoamine oxidases A or B (e.g. phenelzine, isocarboxazid) or within two weeks of taking any such medicinal product. Linzolid should not be administered to patients with uncontrolled hypertension, pheochromocytoma, thyrotoxicosis, carcinoid syndrome and/or patients taking directly and indirectly acting sympathomimetic agents (e.g. pseudoephedrine), vasopressive agents (e.g. epinephrine, norepinephrine), dopaminergic agents (e.g. dopamine, dobutamine), serotonin re-uptake inhibitors, tricyclic antidepressants, serotonin 5-HT1 receptor agonists (triptans), meperidine or buspirone.

Mode of Action

Linezolid is a bacteriostatic oxazolidinone which acts by inhibiting ribosomal protein synthesis. It is active against gm+ve bacteria including vancomycin-resistant enterococci and MRSA. It has limited in vitro activity against gm-ve bacteria.

Precaution

Preexisting myelosuppression, renal impairment (CrCl < 30ml/min), uncontrolled hypertension, phaeochromocytoma, carcinoid syndrome, untreated hyperthyroidism, chronic infection, history of seizures, bipolar depression, schizophrenia or acute confusional states. Pregnancy and lactation. Monitor complete blood counts weekly. Give after haemodialysis. Not known if linezolid or metabolites removed during peritoneal dialysis. Lactation: Unknown; use caution

Side Effect

>10% Pediatrics Diarrhea (7.8-10.8%) 1-10% Headache (5.7-8.8%).Diarrhea (8.2-8.3%),Nausea (5.1-6.6%),Vomiting (2-4.3%),Dizziness (1.8-2.6%),Rash (1.1-2.3%),Vaginal moniliasis (1.1-1.8%),Taste alteration (1-1.8%),Oral moniliasis (0.5-1.7%),Abnormal LFTs (0.4-1.6%),Fungal infection (0.3-1.5%),Localized abdominal pain (1.2-1.3%),Tongue discoloration (0.3-1.3%),Generalized abdominal pain (0.9-1.2%) Pediatrics Vomiting (2.9-9.4%),Headache (0.9-6.5%),Anemia (5.6%),Thrombocytopenia (4.7%),Nausea (1.9-3.7%),Generalized abdominal pain (0.9-2.4%),Localized abdominal pain (0.5-2.4%),Loose stools (1.6-2.3%),Eosinophilia (0.4-1.9%),Pruritus, other than application site (0.8-1.4%),Vertigo (1.2%) <1% Lactic acidosis,Myelosuppression,Peripheral neuropathy,Disorder of optic nerve,Serotonin syndrome Potentially Fatal: Reversible myelosuppression including anaemia, leukopenia, pancytopenia and thrombocytopenia (particularly if using > 10-14 days), transient ischaemic attacks, renal failure, Stevens-Johnson syndrome.

Interaction

May reduce serum levels w/ rifampicin and phenytoin. May cause hypoglycaemia w/ insulin or oral antidiabetics. May increase risk of seizures w/ tramadol. Potentially Fatal: Increased risk of serotonin syndrome w/ MAOIs, TCAs, SNRIs, or other serotonergic drugs (e.g. bupropion, vilazodone, mirtazapine, amoxapine, buspirone, maprotiline, meperidine, trazodone, nefazodone). Significant increase in BP w/ vasopressive agents (e.g. epinephrine, norepinephrine), sympathomimetic agents (e.g. pseudoephedrine) and dopaminergic agents (e.g. dopamine, dobutamine).

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What is the price of Linexil IV Infusion in Bangladesh?

The latest price of Linexil IV Infusion in Bangladesh is 410.28৳. You can buy Linexil IV Infusion at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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UNSAFE
It is unsafe to consume alcohol with Linexil IV Infusion.
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CONSULT YOUR DOCTOR
Linexil IV Infusion may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
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CONSULT YOUR DOCTOR
Linexil IV Infusion is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
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UNSAFE
Linexil IV Infusion may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
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SAFE IF PRESCRIBED
Linexil IV Infusion is safe to use in patients with kidney disease. No dose adjustment of Linexil IV Infusion is recommended. However, talk to your doctor if you have any underlying kidney disease.
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CAUTION
Linexil IV Infusion should be used with caution in patients with severe liver disease. Dose adjustment of Linexil IV Infusion may be needed. Please consult your doctor. Limited information is available on the use of Linexil IV Infusion in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.