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Bugesic

Tablet-(200mcg)
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Beximco Pharmaceuticals Ltd.

Generic: Buprenorphine

1 Tablet
৳ 1
৳ 1

Medicine Overview of Bugesic 200mcg Tablet

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Introduction

Bugesic is used to treat moderate to severe pain and drug dependence/addiction to opioids. It helps to prevent withdrawal symptoms that may be caused due to withdrawal of other opioids. Bugesic is only prescribed to individuals who are at least 16 years of age or above. It may be habit forming and should be taken only as directed by your doctor. The medicine may be a part of your treatment which could include receiving social and psychological support. It can be taken with or without food. You should continue taking this medicine regularly until the doctor tells you it is alright to stop. Try not to miss doses as this will make the medicine less effective. Some common side effects of this medicine include weakness, drug withdrawal syndrome, anxiety, nervousness, dizziness, headache, sleepiness, diarrhea, nausea, vomiting, and abdominal pain. If any of these side effects do not resolve with time or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. To make it sure it is safe for you, before taking this medicine, let your doctor know if you have any medical conditions or disorders. You should also tell your doctor all the other medicines you are using or taking. Pregnant and breastfeeding women should consult their doctors before using this medicine.

Uses of Bugesic

  • Opioid (Morphine) dependence

Side effects of Bugesic

Common
  • Weakness
  • Drug withdrawal syndrome

How to use Bugesic

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bugesic may be taken with or without food, but it is better to take it at a fixed time.

How Bugesic works

Bugesic is a opioid partial agonist. It prevents withdrawal symptoms in patients who stop taking opioid drugs by producing similar effects to these drugs.

Quick Tips

  • Take it at the same time every day to help you remember to take it.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Use caution while driving or doing anything that requires concentration as Bugesic can cause dizziness and sleepiness.
  • Avoid drinking alcohol or taking other medicines that can cause drowsiness.
  • Discontinue the medicine and inform your doctor if you experience difficulty breathing.
  • Do not stop taking Bugesic without talking to your doctor first as it may cause a worsening of symptoms.
  • Your doctor may get regular blood tests to check for liver function while taking this medicine.

Brief Description

Indication

Pain, Anaesthesia, Opioid dependence

Administration

V Preparation Solution: Dilute to final concentration of 15 mcg/mL in D5W, D5/NS, NS, or LR Administer via controlled infusion device IV/IM Administration Administer by deep IM injection, by slow IV injection over >2 minutes, or by continuous IV infusion Also may be given by epidural injection at concentration of 6-30 mcg/mL

Adult Dose

Adult: Sublingual Moderate to severe pain 200-400 mcg 6-8 hrly. IV Perioperative analgesia 300-450 mcg via slow inj. IV/IM Moderate to severe pain 300-600 mcg 6-8 hrly. IM Anesth premed 300 mcg. Elderly: Moderate-to-Severe Pain 0.15 mg IV/IM q6hr; for IV, administered slowly over 2 minutes

Child Dose

Moderate-to-Severe Pain <2 years: Safety and efficacy not established 2-12 years: 2-6 mcg/kg slow IV/IM q4-6hr PRN >12 years: As in adults

Contraindication

Acute alcoholism; convulsive disorders; head injuries; increased intracranial pressure; comatose patients; resp depression and obstructive airway disease; patients on established opioid agonists.

Mode of Action

Buprenorphine exerts its analgesic effect by binding to the mu-opioid receptors in the CNS. It has a longer duration of analgesic action than morphine. Its partial agonist activity gives it a low level of physical dependence. Buprenorphine and morphine show similar dose-related resp depressant effect.

Precaution

Hepatic or renal disease; pregnancy, lactation; hypothyroidism; adrenocortical insufficiency; asthma; prostatic hyperplasia; shock; hypotension; inflammatory or obstructive bowel disorders; myasthaenia gravis; infants/neonates. Reduce dose in elderly and debilitated patients. May precipitate withdrawal symptoms in narcotic addicts. Lactation: Drug enters breast milk; use not recommended

Side Effect

>10% Sedation (2/3 of patients) 1-10% Dizziness,Headache,Hypotension,Hypoventilation,Miosis,Nausea,Sweating,Vertigo,Vomiting <1% Abdominal cramps,Amblyopia,Apnea,Blurred vision,Bradycardia,Coma,Confusion,Conjunctivitis,Constipation,Cyanosis,Depersonalization,Diplopia,Dreaming,Dry mouth,Dyspepsia,Dyspnea,Electrocardiographic (ECG) abnormalities,Euphoria,Fatigue,Flatulence,Hallucinations,Hypertension,Injection-site reactions,Malaise,Mental depression,Mydriasis,Nervousness,Paresthesia,Pruritus,Psychosis,Respiratory depression,Slurred speech,Tachycardia,Urticaria

Pregnancy Category Note

Pregnancy Data in pregnancy are limited; however, these data do not indicate an increased risk of major malformations specifically due to buprenorphine exposure; observational studies reported on congenital malformations among exposed pregnancies, but were also not designed appropriately to assess risk of congenital malformations specifically due to drug exposure Dosage adjustments of buprenorphine may be required during pregnancy, even if patient was maintained on stable dose prior to pregnancy; withdrawal signs and symptoms should be monitored closely and the dose adjusted as necessary Fetal/neonatal adverse reactions Neonatal opioid withdrawal syndrome may occur in newborn infants of mothers who are receiving treatment Lactation Data on two studies in 13 lactating women receiving therapy where the drug and it metabolite were present in low levels in human milk did not show adverse reactions in breastfed infants; developmental and health benefits of breastfeeding should be considered along with mother’s clinical need for therapy and any potential adverse effects on breastfed child from drug or from underlying maternal condition Advise breastfeeding women taking buprenorphine products to monitor infant for increased drowsiness and breathing difficulties

Interaction

Plasma-buprenorphine concentrations may be affected when co-administered with drugs that induce or inhibit cytochrome P450 isoenzyme CYP3A4. Enhanced depressant effects with other CNS depressants e.g. alcohol, anaesthetics, anxiolytics, hypnotics, TCAs and antipsychotics. Potentially Fatal: Diazepam may produce resp and cardiac collapse.

Buy Bugesic from Arogga

In Bangladesh, you can get the original Bugesic. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Bugesic in Bangladesh?

The latest price of Bugesic in Bangladesh is 1৳. You can buy Bugesic at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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UNSAFE
It is unsafe to consume alcohol with Bugesic.
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CONSULT YOUR DOCTOR
Bugesic may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
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CONSULT YOUR DOCTOR
Bugesic is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
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UNSAFE
Bugesic may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
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CAUTION
Bugesic should be used with caution in patients with severe kidney disease. Dose adjustment of Bugesic may be needed. Please consult your doctor.
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CAUTION
Bugesic should be used with caution in patients with liver disease. Dose adjustment of Bugesic may be needed. Please consult your doctor. Use of Bugesic is not recommended in patients with serious liver disease.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.