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Bupi

Injection-(5mg/ml)
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Popular Pharmaceuticals Ltd.

Generic: Bupivacaine

1 Injection
৳ 55.29
৳ 60.22
8% OFF

Medicine Overview of Bupi 5mg/ml Injection

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Introduction

Bupi is a prescription medication used as a local anesthetic. It is used during minor surgical procedures such as dental, oral, diagnostic, or other therapeutic procedures to anesthetize or numb the surgical area. This medicine can also be useful in the relief of pain, e.g. during labor. Bupi blocks the nerve impulses that send pain signals to your brain and helps to perform a painless procedure by temporarily numbing the surgical area. Like many other medicines, this medicine also has few side effects. The most common side effects of this medicine are nausea, tingling sensation, slow heart rate, high blood pressure, dizziness, inability to empty the urinary bladder, etc. These are usually mild and short-lived. If the numbness or other side effects persist, consult your doctor without delay. Before using Bupi, it is very important to tell your doctor if you have any underlying heart disease or are taking medicines for heart rhythm problems. Let your doctor know if you are pregnant or breastfeeding. Also, it is not safe to drive or operate heavy machinery while on medication, unless your doctor permits you to do so.

Uses of Bupi

  • Local anesthesia (Numb tissues in a specific area)

Side effects of Bupi

Common
  • Nausea
  • Paresthesia (tingling or pricking sensation)
  • Slow heart rate
  • Decreased blood pressure
  • Dizziness
  • Urinary retention
  • High blood pressure
  • Vomiting

How to use Bupi

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Bupi works

Bupi is a local anesthetic. It works by blocking the transmission of pain signals from the nerves to the brain. This helps to decrease the sensation of pain.

What if you forget to take Bupi?

If you miss a dose of Bupi, please consult your doctor.

Quick Tips

  • Bupi is given as an injection by the healthcare professional.
  • It may affect your concentration or make you feel sleepy, so avoid driving or using tools or machines until the next day.
  • Consult your doctor immediately if you experience dizziness, lightheadedness, problem with sight or hearing or numbness around lips, tongue and mouth.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Brief Description

Indication

Local anesthesia, Epidural, Intrathecal anesthesia, Epidural analgesia

Adult Dose

Adult: Inj Percutaneous infiltration anesth For prolonged action: 9 mg w/ adrenaline (1 in 200,000), may repeat 2-10 mins later if needed. Max: 90 mg per dental sitting. Surgical anaesthesia Peripheral nerve block 12.5 mg (as 0.25% soln) or 25 mg (as 0.5% soln) . Max: 150 mg/dose. Sympathetic nerve block As 0.25% soln: 50-125 mg. Retrobulbar block As 0.75% soln: 15-30 mg. Caudal block In surgery: 37.5-75 mg (as 0.25% soln) or 75-150 mg (as 0.5% soln). Lumbar epidural block In surgery: 25-50 mg (as 0.25% soln) and 50-100 mg (as 0.5% soln). Spinal block: 0.5% soln: 10-20 mg (2-4 mL). Acute pain Adult: Lumbar block in labour pain: 0.25% soln: 15-30 mg (6-12 mL); 0.375% soln: 22.5-45 mg (6-12 mL); 0.5% soln: 30-60 mg (6-12 mL). Alternatively, 0.1% soln: 10-15 mg (10-15 mL) per hr; 0.125% soln: 10-15 mg (8-12 mL) per hr via infusion. Caudal block in labour pain: 0.25% soln: 25-50 mg (10-20 mL); 0.375% soln: 37.5-75 mg (10-20 mL); 0.5% soln: 50-100 mg (10-20 mL).

Child Dose

<12 years: Not recommended Caudal Block, Epidural Block, Local Block >12 years Local Anesthesia: Infiltration 0.25% infiltrated locally: 175 mg maximum Caudal Block: 15-30 mL of 0.25% or 0.5% (preservative free) Epidural Block Other Than Caudal Block: 10-20 mL of 0.25% or 0.5%; administer in 3-5 mL increments allowing sufficient time to detect toxic manifestations of inadvertent IV or IT administration (preservative free); for surgical procedures requiring high degree of muscle relaxation and prolonged effects administer10-20 mL of 0.75%; not to be used in obstetrical cases Peripheral or Sympathetic Nerve Block >12 years Peripheral Nerve Block: 5 mL of 0.25-0.5%; 400 mg/day maximum Sympathetic Nerve Block: 20-50 mL of 0.25%

Contraindication

Hypersensitivity to local anaesthetics of amide type. IV regional anaesthesia; paracervical block in obstetrics; spinal anaesthesia <18 yr. Lactation. Solutions containing preservatives for caudal or epidural block.

Mode of Action

Bupivacaine blocks both the initiation and conduction of nerve impulses reducing the permeability of neuronal membranes to Na ions resulting in inhibition of depolarization w/ resultant blockade of conduction.

Precaution

Hepatic disease; CV disease; children <12 yr; pregnancy. Elderly and debilitated patients. Lactation: excretion in milk unknown/not recommended

Side Effect

CNS excitation may be followed by depression. Hypotension, bradycardia, arrhythmias and cardiac arrest; methaemoglobinaemia; seizures, restlessness, dizziness. Hypersensitivity. Prolonged block, Edema, Headache, Hypotension, Hypoventilation, Nausea, Nervousness, Palpitation, Respiratory arrest, Tachycardia, Tinnitus, Tremors, Vomiting Potentially Fatal: Cardiac and sudden respiratory arrest.

Pregnancy Category Note

Pregnancy Category: C Lactation: excretion in milk unknown/not recommended

Interaction

Additive systemic toxic effect w/ other local anaesth or agents structurally related to amide-type local anaesth (e.g. lidocaine and mexiletine). Increased risk of myocardial depression w/ antiarrhythmics. Enhanced adverse effects w/ hyaluronidase. Decreased clearance resulting to increased plasma concentrations w/ cimetidine and ranitidine. Increased risk of adverse effects w/ beta-blockers and Ca channel blockers.

Buy Bupi from Arogga

In Bangladesh, you can get the original Bupi. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Bupi in Bangladesh?

The latest price of Bupi in Bangladesh is 55.29. You can buy Bupi at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Bupi. Please consult your doctor.
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CONSULT YOUR DOCTOR
Bupi may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
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SAFE IF PRESCRIBED
Bupi is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
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UNSAFE
Bupi may cause side effects which could affect your ability to drive. Bupi may cause numbness to certain areas of the body for about 2-4 hours after having it. You should wait for the effect to wear off as this may affect your ability to drive
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CAUTION
Bupi should be used with caution in patients with kidney disease. Dose adjustment of Bupi may be needed. Please consult your doctor.
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CAUTION
Bupi should be used with caution in patients with liver disease. Dose adjustment of Bupi may be needed. Please consult your doctor.
Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.