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ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন

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Tplase 50

Injection-(5ml/50mg)
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Healthcare Pharmaceuticals Ltd.

Generic: Tenecteplase

1 x 1's Pack
৳ 52772.50
৳ 55000
4% OFF

Medicine Overview of Tplase 50 5ml/50mg Injection

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Introduction

Tplase 50 belongs to a group of medicines called thrombolytic agents. It is used in the emergency treatment of heart attack. It helps to dissolve blood clots that have formed in the blood vessels of the heart. Tplase 50 is an injectable drug, given directly into a vein and it is given by a doctor as soon as possible after the first signs of a heart attack. Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely. You may be given another medicine to stop blood clotting at the same time or after the treatment. This medicine may increase your risk of bleeding, so its better to be careful while shaving, cutting nails, or using sharp objects. Treatment with this drug can also cause nausea, vomiting, decreased blood pressure, and injection site bleeding. This drug needs to be administered with care by an expert and is not suitable for everyone. There is a long list of situations where you will not be given Tplase 50 including if you've had a head injury, or surgery on your brain or spinal cord and any current bleeding anywhere in your body. Your healthcare team will need to know a lot about your medical history before giving you this medicine.

Uses of Tplase 50

  • Heart attack

Side effects of Tplase 50

Common
  • Injection site bleeding
  • Nosebleeds
  • Blood in stool
  • Blood in urine
  • Gastrointestinal bleeding

How to use Tplase 50

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Tplase 50 works

Tplase 50 is a thrombolytic medication. It works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected tissue, thereby preventing tissue death and improving outcomes.

Quick Tips

  • Tplase 50 is used to treat myocardial infarctions (heart attacks) as soon as possible (usually within 12 hours) after the onset of symptoms.
  • It is given as an injection into the vein under the supervision of a doctor.
  • It may increase your risk of bleeding. Inform your doctor immediately if you notice bleeding at the injection site, nose bleed, and blood in urine.
  • Continue with your diet and exercise along with previously prescribed medications for heart attack.

Brief Description

Indication

Acute myocardial infarction

Administration

IV Preparation Add 10 mL SWI to a 50 mg vial using TwinPak® device directing stream of diluent into powder. If foaming (usually slight) occurs, leave vial undisturbed for several minutes to allow dissipation of any large bubbles. Gently swirl (do not shake) until contents are completely dissolved.

Adult Dose

Intravenous Acute myocardial infarction Adult: 30-50 mg as a single bolus dose over 5-10 sec as soon as possible after the onset of symptoms. The dose is based on body weight. Max: 50mg. Administer ASAP (within 30 minutes) after onset of acute MI 30-50 mg IV bolus over 5 sec once (based on weight) <60 kg: 30 mg 60-70 kg: 35 mg 70-80 kg: 40 mg 80-90 kg: 45 mg >90 kg: 50 mg

Contraindication

Patients at risk of cerebral bleeding including severe hypertension, history of stroke, intracranial or intraspinal surgery or trauma within 2 mth, arteriovenous malformation or aneurysm, cerebral neoplasm. Haemorrhage or known bleeding diathesis.

Mode of Action

Tenecteplase is a biosynthetic form of the enzyme human tissue-type plasminogen activator (t-PA). It is a fibrin-specific thrombolytic, converts plasminogen to plasmin, a proteolytic enzyme that has fibrinolytic effects.

Precaution

Patients with increased risk of bleeding. Recent history of GI or genitourinary bleed, recent major surgery, previous puncture of noncompressible vessels, hypertension (>180/110 mm Hg), high risk of left heart thrombus, acute pericarditis, subacute bacterial endocarditis, coagulation defects, invasive procedures, haemorrhagic ophthalmic conditions. Elderly, pregnancy and lactation. Severe hepatic impairment. Lactation: not known whether drug crosses into breast milk, nursing not a priority in AMI

Side Effect

>10% Minor bleeding (22%) Frequency Not Defined Reperfusion arrhythmias MI Fever Nausea Vomiting Cholesterol embolization Allergic reaction

Interaction

Increased risk of haemorrhage with heparin, oral anticoagulants, antiplatelet drugs and other drugs that can affect platelet function.

Buy Tplase 50 from Arogga

In Bangladesh, you can get the original Tplase 50. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Tplase 50 in Bangladesh?

The latest price of Tplase 50 in Bangladesh is 52772.5৳. You can buy Tplase 50 at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Tplase 50. Please consult your doctor.
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CONSULT YOUR DOCTOR
Tplase 50 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
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CAUTION
Tplase 50 should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
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NOT RELEVANT
Not relevant, as Tplase 50 is intended for use in hospitalised patients.
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CONSULT YOUR DOCTOR
There is limited information available on the use of Tplase 50 in patients with kidney disease. Please consult your doctor.
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CONSULT YOUR DOCTOR
There is limited information available on the use of Tplase 50 in patients with liver disease. Please consult your doctor.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.