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Carplatin 450

Injection-(450mg/45ml)
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Drug International Ltd.

Generic: Carboplatin

1 Injection
৳ 3330
৳ 3700
10% OFF

Medicine Overview of Carplatin 450mg/45ml Injection

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Introduction

Carplatin 450 is used in the treatment of ovarian cancer and small cell lung cancer. It shows its working by stopping or slowing down the growth of cancer cells. Carplatin 450 is given as an injection into veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Nausea, vomiting, fatigue, and increased liver enzyme are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections or bleeding. Inform your doctor if you notice fever, sore throat, chills, unusual bleeding or bruising, and dark urine. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels. You must inform your doctor if you experience allergic reactions with injection such as skin rash, itching, and trouble breathing. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Carplatin 450

  • Ovarian cancer
  • Small cell lung cancer

Side effects of Carplatin 450

Common
  • Nausea
  • Vomiting
  • Anemia (low number of red blood cells)
  • Fatigue
  • Low blood platelets
  • Increased liver enzymes
  • Decreased white blood cell count (neutrophils)
  • Stomatitis (Inflammation of the mouth)
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Diarrhea

How to use Carplatin 450

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Carplatin 450 works

Carplatin 450 is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and multiplication.

What if you forget to take Carplatin 450?

If you miss a dose of Carplatin 450, please consult your doctor.

Quick Tips

  • It is given as an injection into the veins under the supervision of a doctor.

Brief Description

Indication

Ovarian carcinoma, Lung cancer

Administration

IV Preparation Single-dose lyophilized powder (reconstitution require) Reconstitute powder with sterile water for injection, D5W, or 0.9% NaCl to yield a final concentration of 10 mg/mL Can be further diluted to concentrations as low as 0.5 mg/mL with D5W or 0.9% NaCl Multidose premixed injectable solution Available as a 10 mg/mL aqueous solution Can be further diluted to concentrations as low as 0.5 mg/mL with D5W or 0.9% NaCl IV Administration Administer IV over 15 min or continuous IV infusion over 24 hr May also be administered intraperitoneally When administered as sequential infusions, taxane derivatives (docetaxel, paclitaxel) should be administered before platinum derivatives to limit myelosuppression and to enhance efficacy Do not use aluminum-containing needles or IV administration sets that may come in contact with carboplatin (aluminum can cause precipitate formation and loss of potency)

Adult Dose

Intravenous Small cell lung cancer; Advanced ovarian carcinoma Adult: IV As single agent in treatment-naive patients: 400 mg/m2; As single agent in previously treated patients: 360 mg/m2; W/ cyclophosphamide in treatment-naive patients: 300 mg/m2. Doses to be given not more frequently than every 4 wk. Adjust subsequent doses based on nadir of WBC and platelet counts. Hepatic Impairment Dose adjustment may not be necessary; not studied

Child Dose

Solid tumor 300-600 mg/m² IV q4Weeks Sarcoma (bone/soft tissue) 400 mg/m²/day for 2 days every 21 days Brain tumor 175 mg/m² qWeek x 4 weeks with a 2 weeks recovery period between courses Bone marrow transplant preparative regimen 500 mg/m²/day x 3 days Retinoblastoma 1-2 mL subconjunctival injection of 10 mg/mL solution per dose

Renal Dose

Renal impairment: CrCl (ml/min) >40 Recommended dose: 400 mg/m2. 20-39 Recommended dose: 250 mg/m2.

Contraindication

Previous allergy; pregnancy, lactation; allergy to other platinum compounds; severe bone marrow depression; significant bleeding, aluminium containing needles and IV sets.

Mode of Action

Carboplatin is an alkylating agent which binds covalently to DNA. It modifies the cell cycle by interfering with DNA structure and function.

Precaution

Neonates; diminished renal function; neurotoxicity; liver function impairment. Lactation: not known if excreted in breast milk; do not nurse

Side Effect

>10% Leukopenia (26-97%),Neutropenia (21-96%),Nausea (81-93%),Vomiting (81-93%),Anemia (14-90%),Magnesium loss (43-61%),Thrombocytopenia (33-66%),Alopecia (2-49%),Asthenia (11-41%),Elevated alkaline phosphatase (29-37%),Central neurotoxicity (5-26%),Elevated AST (19-20%),Peripheral neuropathy (6-15%) 1-10% Immune hypersensitivity reaction (2-9.2%),Elevated bilirubin (5%) Frequency Not Defined Visual disturbance (rare) Potentially Fatal: Bone marrow suppression and anaphylactic reactions.

Pregnancy Category Note

Pregnancy Category: D Lactation: not known if excreted in breast milk; do not nurse

Interaction

Increased risk of ototoxicity when used with aminoglycosides.

Buy Carplatin 450 from Arogga

In Bangladesh, you can get the original Carplatin 450. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Carplatin 450 in Bangladesh?

The latest price of Carplatin 450 in Bangladesh is 3330৳. You can buy Carplatin 450 at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Carplatin 450. Please consult your doctor.
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CONSULT YOUR DOCTOR
Carplatin 450 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
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UNSAFE
Carplatin 450 is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
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UNSAFE
Carplatin 450 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
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CAUTION
Carplatin 450 should be used with caution in patients with kidney disease. Dose adjustment of Carplatin 450 may be needed. Please consult your doctor. Use of Carplatin 450 is not recommended in patients with severe kidney disease. Regular monitoring of kidney function tests may be advised while you are taking this medicine.
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SAFE IF PRESCRIBED
Carplatin 450 is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Carplatin 450 may not be needed in these patients. Please consult your doctor.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.