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Adribin 50

Injection-(2mg/ml)
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Healthcare Pharmaceuticals Ltd.
1 x 50mg vial
৳ 1022.12
৳ 1100
7% OFF

Medicine Overview of Adribin 50 2mg/ml Injection

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Introduction

Adribin 50 is used in the treatment of some kinds of cancer. It is also used in the treatment of breast cancer, where there is an increased cardiac risk. It can be used on its own, or sometimes given together with certain other medicines as part of combination chemotherapy. Adribin 50 can be used in both adults and children. It is given as injection into vein with extreme caution by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes contraceptive pills less effective, so it advised to use reliable contraception during and after 6 months of the treatment. The most common side effects of this medicine include nausea, vomiting, rash, weakness, low blood platelets. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lead to problems with your blood, liver or heart. Your doctor will advise you regular blood tests to check for these. Before taking this medicine, let your doctor know if you have liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding.

Uses of Adribin 50

  • Cancer

Side effects of Adribin 50

Common
  • Nausea
  • Vomiting
  • Rash
  • Weakness
  • Low blood platelets
  • Fatigue
  • Fever
  • Decreased white blood cell count (neutrophils)
  • Loss of appetite
  • Anemia (low number of red blood cells)
  • Constipation
  • Stomatitis (Inflammation of the mouth)
  • Diarrhea
  • Painful blisters on hands and feet

How to use Adribin 50

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Adribin 50 works

Adribin 50 is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

Quick Tips

  • Adribin 50 helps treat cancer of the breast, blood, and ovaries.
  • It is given through a drip into a vein (intravenous infusion) by a doctor or nurse.
  • It may make you feel tired or sleepy. Do not drive or do anything that requires mental focus until you know how it affects you.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for 6 months after stopping treatment.
  • Inform your doctor if you notice sores, discolouration or any discomfort in your mouth.
  • Your doctor may get regular blood tests done to monitor your blood cells, liver, and heart function during treatment with this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.

Brief Description

Indication

AIDS-related Kaposi's sarcoma, Ovarian carcinoma, Metastatic breast carcinoma, bladder carcinoma

Adult Dose

Intravenous As Doxorubicin liposomal Kaposi's Sarcoma Indicated for AIDS-related Kaposi’s sarcoma in patients after failure of prior systemic chemotherapy or intolerance to such therapy 20 mg/m² IV q3Weeks Ovarian Cancer Indicated for ovarian cancer in patients whose disease has progressed or recurred after platinum-based chemotherapy 50 mg/m² IV q4Weeks x 4 courses minimum Multiple Myeloma Indicated in combination with bortezomib for multiple myeloma in patients who have not previously received bortezomib and have received at least 1 prior therapy 30 mg/m² IV on day 4 following bortezomib 1.3 mg/m² on days 1, 4, 8 & 11 q3Weeks Metastatic breast cancer Adult: 60-75 mg/m2 BSA once every 3 wk in combination with cyclophosphamide given as an infusion over 1 hr diluted in 0.9% sodium chloride or 5% glucose. Irrigation Local malignant neoplasms in the bladder Adult: 50 ml of a 1 mg/ml solution instilled into the bladder for 1 hr once a mth. Hepatic Impairment Serum bilirubin <1.2 mg/dL: Dose adjustment not necessary Serum bilirubin 1.2-3 mg/dL [20.5-51.3 micromoles/L]: Give 50% dose Serum bilirubin: 3.1-5 mg/dL [53-85.5 micromoles/L]: Give 25% dose Severe hepatic impairment: Contraindicated

Child Dose

Safety and efficacy not established

Renal Dose

Renal Impairment Dose adjustment not necessary

Contraindication

Cardiac disease, neonates, pregnancy and lactation, prior irradiation to mediastinum. IM/SC admin. Severe myelosuppression due to previous treatment with antitumour agents or radiotherapy.

Mode of Action

Doxorubicin is a cytotoxic anthracycline antibiotic. The cytotoxic action results from its binding to DNA and inhibition of nucleic acid synthesis. Doxorubicin has been shown to produce regression in a variety of disseminated malignancies.

Precaution

Elderly, children, hepatic impairment. Monitor blood counts and ECG. Lactation: Enters breast milk/not recommended

Side Effect

>10% Kaposi's Sarcoma Anemia (>50%),Thrombocytopenia (>50%),Neutropenia (10-50%),Anemia (18.2%),Nausea (17%) Ovarian cancer >25% Hand-foot syndrome (50%),Nausea (46%),Stomatitis (41%),Asthenia (40.2%),Vomiting (32.6%),Rash (28%),Constipation (>25%),Abdominal pain (>25%) Ovarian cancer 10-25% Fever (21.3%),Anorexia (20%),Diarrhea (20%),Peripheral edema,Dyspepsia,Pharyngitis,Dyspnea,Alopecia 1-10% Kaposi's Sarcoma 5-10% Asthenia (9.9%),Fever (9.1%),Diarrhea (7.8%),Vomiting (7.8%),Stomatitis (6.8%),Rash (1-5%),Alopecia (1-5%),Increased alkaline phosphatase Kaposi's Sarcoma 1-5% Hand-foot syndrome (3.4%),Hypotension,Tachycardia,Dyspnea,Hemolysis,Rash Ovarian cancer (selected) Neutropenia (13.3%),Anemia (0.4-5.4%),Thrombocytopenia (1.3%) <1% Abscess,Acute myeloid leukemia,Cardiomegaly,Cardiomyopathy,Erythema nodosum,Hyperkalemia,Hyperuricemia,Ketosis Potentially Fatal: Bone marrow suppression, cardiotoxicity.

Pregnancy Category Note

Pregnancy Category: D Lactation: Enters breast milk/not recommended

Interaction

Doxorubicin interacts with a number of other drugs e.g. antibiotics (aminoglycosides), steroids, aminophylline and propranolol. Potentially Fatal: Cholestasis induced by mercaptopurine may be potentiated by concurrent administration of the drug. Toxicity may be increased if streptozocin is given concurrently.

Buy Adribin 50 from Arogga

In Bangladesh, you can get the original Adribin 50. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Adribin 50 in Bangladesh?

The latest price of Adribin 50 in Bangladesh is 1022.12. You can buy Adribin 50 at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Adribin 50. Please consult your doctor.
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CONSULT YOUR DOCTOR
Adribin 50 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
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CONSULT YOUR DOCTOR
Information regarding the use of Adribin 50 during breastfeeding is not available. Please consult your doctor.
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UNSAFE
Adribin 50 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
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SAFE IF PRESCRIBED
Adribin 50 is safe to use in patients with kidney disease. No dose adjustment of Adribin 50 is recommended. Caution is advised in patients with severe kidney disease as the information available is limited for use of this medicine in these patients.
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CAUTION
Adribin 50 should be used with caution in patients with liver disease. Dose adjustment of Adribin 50 may be needed. Please consult your doctor. Use of Adribin 50 is not recommended in patients with severe liver disease.
Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.