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Safety Advices
বাংলা
English
SAFE
Consuming alcohol with Kanamycin-POS does not cause any harmful side effects.
CONSULT YOUR DOCTOR
Kanamycin-POS is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
SAFE IF PRESCRIBED
Kanamycin-POS is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
UNSAFE
Kanamycin-POS may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CAUTION
Kanamycin-POS should be used with caution in patients with kidney disease. Dose adjustment of Kanamycin-POS may be needed. Please consult your doctor.
CONSULT YOUR DOCTOR
There is limited information available on the use of Kanamycin-POS in patients with liver disease. Please consult your doctor.
Medicine Overview of Kanamycin-POS 0.5% Eye Drop
Introduction
Kanamycin-POS is an antibiotic used to treat a wide variety of bacterial infections. This may include infections of the urinary tract, bones and joints, lungs (eg. pneumonia), blood, and some others. It is also used in the treatment of resistant tuberculosis. Kanamycin-POS works by stopping the growth of bacteria. It is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle under the supervision of a healthcare professional. It should be used regularly at evenly spaced time intervals as prescribed by your doctor. Do not skip any doses and finish the full course...
... Show moreUses of Kanamycin-POS
- Bacterial infections
- Tuberculosis (TB)
Side effects of Kanamycin-POS
Common
- Hearing loss
- Balance disorder (loss of balance)
- Injection site pain
- Renal impairment
How to use Kanamycin-POS
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Kanamycin-POS works
Kanamycin-POS is an antibiotic. It stops bacterial growth by preventing synthesis of essential proteins required by bacteria to carry out vital functions.
What if you forget to take Kanamycin-POS?
If you miss a dose of Kanamycin-POS, please consult your doctor.
Quick Tips
- Your doctor has prescribed Kanamycin-POS to cure your infection and improve your symptoms.
- Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
- It is given by an injection into a muscle.
- Use caution while driving or doing anything that requires concentration as Kanamycin-POS may cause dizziness.
- Your doctor may get regular blood, urine, or hearing tests while you are on this medication.
- Your doctor will ensure that you are well hydrated before and during treatment with this medicine.
- Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
- Discontinue Kanamycin-POS and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
- Your doctor has prescribed Kanamycin-POS to cure your infection and improve your symptoms.
- Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
- It is given by an injection into a muscle.
- Use caution while driving or doing anything that requires concentration as Kanamycin-POS may cause dizziness.
- Your doctor may get regular blood, urine, or hearing tests while you are on this medication.
- Your doctor will ensure that you are well hydrated before and during treatment with this medicine.
- Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
- Discontinue Kanamycin-POS and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
Brief Description
Indication
Susceptible Infections
Administration
IV Preparation
For adults, IV infusions are prepared by adding 500 mg of kanamycin to 100-200 mL of usual IV infusion fluid such as NS or D5W or by adding 1 g of the drug to 200-400 mL of diluent
IV/IM Administration
Administer by deep IM injection, or IV infusion
May administer by intraperitoneal instillation, irrigation, or inhalation
Infuse over 30-60 min
Adult Dose
Susceptible Infections
IV Administration: 5-7.5 mg/kg/dose divided q8-12hr; not to exceed 15 mg/kg/day divided q6-12hr; administer slowly
IM Administration: 5-7.5 mg/kg/dose divided q8-12hr; not to exceed 15 mg/kg/day IM divided q12hr at equally divided intervals; continuously high blood levels are desired; daily dose of 15 mg/kg may be given divided q6-8hr
Aerosol: 250 mg q6-12hr by nebulization
Renal Dose
Renal Impairment
CrCl 50-80 mL/min: give 60-90% of usual dose or give q8-12hr
CrCl 10-50 mL/min: give 30-70% of usual dose or give q12hr
CrCl <10 mL/min: give 20-30% of usual dose or give q24-48hr
Contraindication
Documented hypersensitivity
Mode of Action
Bactericidal
Aminoglycoside contain 1 or 2 amino sugars linked to an aminocyclitol nucleus. Nucleus is 2-deoxystreptamine. Bactericidal and believed to inhibit protein synthesis by binding to 30 S ribosomal subunit.
Precaution
Auditory toxicity more common with kanamycin than with streptomycin and capreomycin; monthly audiometry is recommended while patients are being treated with this drug; vestibular toxicity is rare; renal toxicity occurs at a frequency similar to that of capreomycin; regular monitoring of serum creatinine recommended Neurotoxicity, manifested as both bilateral auditory and vestibular ototoxicity, can occur in patients with preexisting renal damage and in patients with normal renal function treated at higher doses and/or for periods longer than those recommended. High-frequency deafness usually occurs first and can be detected only by audiometric testing. Vertigo may occur and may be evidence of...
... Show moreSide Effect
Frequency Not Defined
Agranulocytosis
Anorexia
Diarrhea
Dyspnea
Edema
Elevated BUN
Enterocolitis
Headache
Incr salivation
Muscle cramps
Muscle weakness
Nausea
Nephrotoxicity
Neurotoxicity
Ototoxicity
Pruritus
Pseudotumor cerebri
Rash
Tinnitus
Thrombocytopenia
Tremor
Vertigo
Weakness
Pregnancy Category Note
Pregnancy Category: D
Lactation: usually compatible
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Disclaimer
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.