12-24 Hours
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Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Clof 100.
CONSULT YOUR DOCTOR
Clof 100 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Information regarding the use of Clof 100 during breastfeeding is not available. Please consult your doctor.
UNSAFE
Clof 100 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CAUTION
Clof 100 should be used with caution in patients with kidney disease. Dose adjustment of Clof 100 may be needed. Please consult your doctor.
Use of Clof 100 is not recommended in patients with severe kidney disease.
CAUTION
Clof 100 should be used with caution in patients with liver disease. Dose adjustment of Clof 100 may be needed. Please consult your doctor.
Use of Clof 100 is not recommended in patients with severe liver disease. Regular monitoring of liver function tests is advisable while the patient is taking this medicine.
Medicine Overview of Clof 100mg Tablet
Introduction
Clof 100 is a pain relieving medicine. It alleviates pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis and osteoarthritis. Clof 100 should be taken in the dose and duration as advised by your doctor. It should be taken with food or milk to prevent stomach upset. Taking the medicine regularly at the right times increases its effectiveness. It is important to keep taking the medicine regularly until your doctor tells you it is safe to stop. Vomiting, stomach pain, nausea, and indigestion are some of the common side effects that might be observed on taking this medicine. It...
... Show moreUses of Clof 100
- Pain relief
Side effects of Clof 100
Common
- Vomiting
- Stomach pain/epigastric pain
- Nausea
- Indigestion
- Diarrhea
- Heartburn
- Loss of appetite
How to use Clof 100
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clof 100 is to be taken with food.
How Clof 100 works
Clof 100 is a non-steroidal anti-inflammatory drugs (NSAID). It works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).
Quick Tips
- You have been prescribed Clof 100 to relieve pain and inflammation.
- Take it with food or milk to prevent upset stomach.
- Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
- It may cause dizziness, drowsiness or visual disturbances. Use caution while driving or doing anything that requires concentration.
- Avoid consuming alcohol while taking Clof 100 as it can cause excessive drowsiness and increase your risk of stomach problems.
- Inform your doctor if you have a history of heart disease or stroke.
- Your doctor may regularly monitor your kidney function, liver function and levels of blood components, if you are taking this medicine for long-term treatment.
Brief Description
Indication
Adult: PO Ankylosing spondylitis; Osteoarthritis; Rheumatoid arthritis
100 mg twice daily.
SR Tablet : The recommended dose is 200 mg, once daily.
Elderly: The pharmacokinetics of aceclofenac are not altered in elderly patients, therefore it is not considered necessary to modify the dose and dose frequency.
Hepatic Impairment Reduce initial dose to 100 mg daily .
Administration
May increase plasma concentrations of lithium and digoxin. Increased nephrotoxicity when used with diuretics or ciclosporin. Monitor serum potassium when used with potassium-sparing diuretics and ACE inhibitors. May enhance activity of anticoagulants. May increase risk of methotrexate toxicity when administered within 24 hr of methotrexate admin. Increased risk of GI bleed with other NSAIDs. Increased risk of convulsion with quinolones.
Adult Dose
Cautiously administer to patients with GI disease, ulcerative colitis, Crohn's disease, haematological abnormalities, hepatic porphyria; history of bronchial asthma; history of heart failure or hypertension; mild renal, hepatic or cardiac impairment. May impair ability to drive or operate machinery. Elderly. Patients suffering from severe hepatic impairment must be monitored.
Renal Dose
Aceclofenac, a phenylacetic acid derivative, has antiinflammatory and analgesic properties. It is a potent inhibitor of cyclo-oxygenase which is involved in the production of prostaglandins.
Contraindication
Safety & Efficacy not established.
Mode of Action
Should be taken with food. Take w/ or immediately after meals.
Precaution
Indicated for the relief of pain and inflammation in both acute and chronic pain like, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, post-traumatic pain, low back pain, gynaecological pain.
Side Effect
No dose adjustment needed.
Pregnancy Category Note
Gastrointestinal disorders (dyspepsia, abdominal pain, nausea and diarrhoea) and occasional occurance of dizziness. Dermatological side effects including pruritus and rash. Abnormal hepatic enzyme levels and raised serum creatinine have occasionally been reported.
Potentially Fatal: Severe GI bleeding; nephrotoxicity; blood dyscrasias.
Interaction
Hypersensitivity to aspirin or NSAIDs; moderate to severe renal impairment; pregnancy (3rd trimester); history of peptic ulceration or GI bleed; patients with infections.
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