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Demarin

Tablet-(600mg)
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ACI Limited

Generic: Oxaprozin

1 Tablet
৳ 6.41
৳ 7.05
9% OFF

Medicine Overview of Demarin 600mg Tablet

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Introduction

Demarin is a pain relieving medicine. It provides relief to pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, gout, and juvenile arthritis. It also helps in relieving muscle and joint pain, headache, fever, toothache, and menstrual cramps. Demarin should be taken with food to avoid stomach upset and reduce side effects. In general, you should try to use the smallest amount necessary to control your symptoms, for the shortest possible time. You should take this medicine regularly while you need it. Try not to miss doses as it will become less effective if you do. The common side effects of this medicine include vomiting, stomach pain, nausea, and indigestion. If any of these side effects do not resolve with time or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. This medicine is generally considered safe but is not suitable for everybody. Before you take it, you should tell your doctor if you have kidney problems, asthma, blood disorders or drink a lot of alcohol. Also, tell your doctor what other medicines you are taking to make sure you are safe. It is best to avoid drinking alcohol while using this medicine.

Uses of Demarin

  • Fever
  • Headache
  • Arthralgia (joint pain)
  • Muscle pain
  • Dental pain
  • Post operative pain
  • Pain during menstruation
  • Osteoarthritis
  • Rheumatoid arthritis
  • Ankylosing spondylitis
  • Gout

Side effects of Demarin

Common
  • Vomiting
  • Nausea
  • Indigestion

How to use Demarin

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Demarin may be taken with or without food, but it is better to take it at a fixed time. Avoid Demarin with herbs/food with anti-platelet activity such as alfalfa, anise, bilberry, grape seed, green tea, turmeric, fenugreek, garlic, ginger.

How Demarin works

Demarin is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).

Quick Tips

  • You have been prescribed Demarin to relieve pain and inflammation.
  • Take it with food or milk to prevent upset stomach.
  • Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
  • Do not take indigestion remedies (antacids) within two hours of taking Demarin.
  • Avoid consuming alcohol while taking Demarin as it can increase your risk of stomach problems.
  • Inform your doctor if you have a history of heart disease or stroke.
  • Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.

Brief Description

Indication

Rheumatoid arthritis, Osteoarthritis, Juvenile rheumatoid arthritis

Administration

Take with food or water to avoid GI effects

Adult Dose

Osteoarthritis Initial in mild to moderate disease: 600mg PO qDay Usual in moderate to severe disease: 1200mg PO qDay Maximum 1,800 mg/day or 26 mg/kg/day, whichever is lower, divided PO q12hr Rheumatoid Arthritis 1200mg PO qDay (individualize) Maximum 1,800 mg/day or 26 mg/kg/day, whichever is lower, divided PO q12hr Hepatic Impairment Caution in patients with severe liver impairment

Child Dose

Juvenile Rheumatoid Arthritis <6 years Safety and efficacy not established >6 years 22-31 kg: 600 mg PO qDay 32-54 kg: 900 mg PO qDay >55 kg: 1200 mg PO qDay

Renal Dose

Renal Impairment Severe renal impairment or on dialysis: 600 mg PO qDay; may increase to 1200 mg/day; monitor closely

Contraindication

Previous or active peptic ulceration, known hypersensitivity to NSAIDs. Perioperative pain in CABG setting.

Mode of Action

Oxaprozin is a propionic acid derivative NSAID. It inhibits the enzyme cyclooxygenase resulting in the blockage of prostaglandin synthesis.

Precaution

Be alert for ulceration and bleeding in patients treated chronically. History of serious GI events, alcoholism, smoking, other factors known to be associated with peptic ulcer. Elderly or debilitated patients. Uncompensated cardiac failure, history of hypertension, cardiac decompensation, chronic diuretic therapy, conditions predisposing to fluid retention. Renal and hepatic impairment. Underlying coagulation defects or patients who are undergoing surgical procedures where a high degree of haemostasis is required. Pregnancy (avoid in 3rd trimester) and lactation. Lactation: not known whether excreted in breast milk; effect on infant unknown

Side Effect

Common Edema,Rash,Abdominal pain,Anorexia,Constipation,Diarrhea,Indigestion,Nausea/Vomiting,GI ulcer,Gross bleeding with perforation,Heartburn,Anemia,LFT's increased.Tinnitus,Dysuria, Increased frequency of urination,Myocardial infarction (<2%) <1% Hypertension (<1%),Palpitations (<1%),Thrombotic tendency observations,Erythema multiforme (rare),Scaling eczema,Stevens-Johnson syndrome (rare),Toxic epidermal necrolysis (rare),Cerebrovascular accident,Gastrointestinal hemorrhage (<1%),Agranulocytosis (rare),Leukopenia (<1%),Thrombocytopenia (<1%),Hepatitis (rare),Jaundice, Liver failure,Anaphylactoid reaction (<1%),Amblyopia (<1%),Hearing loss (<1%),Acute renal failure (rare),Hematuria (rare),Interstitial nephritis (rare),Bronchospasm,Serum sickness due to drug (rare) Potentially Fatal: Anaphylactoid reactions, exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, severe hepatic reactions.

Pregnancy Category Note

Pregnancy Category: C; D in 3rd trimester or near delivery.

Interaction

Increased risk of salicylate toxicity with aspirin. May increase effects of oral anticoagulants. May reduce effects of beta-blockers, diuretics and other antihypertensive agents. May increase risk of methotrexate and lithium toxicity.

Buy Demarin from Arogga

In Bangladesh, you can get the original Demarin. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Demarin in Bangladesh?

The latest price of Demarin in Bangladesh is 6.41. You can buy Demarin at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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UNSAFE
It is unsafe to consume alcohol with Demarin.
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CONSULT YOUR DOCTOR
Demarin may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
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CONSULT YOUR DOCTOR
Demarin is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
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UNSAFE
Demarin may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
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CAUTION
Demarin should be used with caution in patients with kidney disease. Dose adjustment of Demarin may be needed. Please consult your doctor.
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CAUTION
Demarin should be used with caution in patients with liver disease. Dose adjustment of Demarin may be needed. Please consult your doctor. Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine.
Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.