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Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Dobutamine Panpharma. Please consult your doctor.
SAFE IF PRESCRIBED
Dobutamine Panpharma is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Dobutamine Panpharma is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
UNSAFE
Dobutamine Panpharma may cause side effects which could affect your ability to drive.
SAFE IF PRESCRIBED
Dobutamine Panpharma is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Dobutamine Panpharma may not be needed in these patients. Please consult your doctor.
CONSULT YOUR DOCTOR
There is limited information available on the use of Dobutamine Panpharma in patients with liver disease. Please consult your doctor.
Medicine Overview of Dobutamine Panpharma 250mg/20ml Infusion
Introduction
Dobutamine Panpharma is a medicine used for short-term treatment of cardiac decompensation (low blood pressure due to poorly functioning heart) due to disease like heart failure, cardiogenic shock, or heart attack. It increases the blood pressure by increasing the pumping capacity of the heart. Dobutamine Panpharma is also used while performing stress echocardiography evaluation of the heart. It is administered under the supervision of a doctor as it requires continuous blood pressure monitoring. The dose has to be individually adjusted as per the patient's response to therapy. You should continue all your other medicines that are advised by the doctor...
... Show moreUses of Dobutamine Panpharma
- Heart failure
- Low blood pressure
Side effects of Dobutamine Panpharma
Common
- High blood pressure
- Insomnia (difficulty in sleeping)
How to use Dobutamine Panpharma
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Dobutamine Panpharma works
Dobutamine Panpharma is a sympathomimetic agonist. It works by activating the receptors in the heart. This makes the heart pump blood with more strength and force and increases its pumping capacity in conditions such as heart failure.
What if you forget to take Dobutamine Panpharma?
If you miss a dose of Dobutamine Panpharma, please consult your doctor.
Quick Tips
- It is given into the vein as a drip by a healthcare professional.
- Your doctor may perform regular blood tests to monitor the level of sodium and potassium in the blood.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Brief Description
Indication
Heart failure, Cardiac stress test
Administration
IV Preparation Solution: Dilute 250 mg in 250 mL of compatible solution to yield final concentration of 1000 mcg/mL; not to exceed 5000 mcg/mL The rate of administration and the duration of therapy should be adjusted according to the patient's response, The indicators are: haemodynamic parameters such as heart rate and rhythm, arterial pressure, and, whenever possible, cardiac output and measurements of ventricular filling pressures and signs of pulmonary congestion. Because of its short half-life, Dobutamine Hydrochloride must be administered as a continuous intravenous infusion. Following the initiation of a constant rate infusion, or upon changing the rate, a steady-state...
... Show moreAdult Dose
Cardiac Decompensation
0.5-1 mcg/kg/min IV continuous infusion initially, then 2-20 mcg/kg/min; not to exceed 40 mcg/kg/min
Adjust according to patient's BP, heart rate, cardiac and urine output.
Child Dose
Cardiac Decompensation
0.5-1 mcg/kg/min IV continuous infusion initially, then 2-20 mcg/kg/min; not to exceed 40 mcg/kg/min
Contraindication
Hypersensitivity; idiopathic hypertrophic subaortic stenosis (IHSS).
Mode of Action
Dobutamine increases contractility and heart rate by stimulating ?-adrenergic receptors in the cardiac tissues.
Precaution
Correct hypovolaemia prior to treatment. Increased risk of rapid ventricular response in patients with atrial fibrillation. Insufficient data to determine the safety and efficacy of dobutamine use after acute MI. Elderly. Neonates. Pregnancy.
Lactation: Unknown whether drug is excreted into breast milk; avoid use
Side Effect
1-10%
Tachyarrhythmia (10%),Hypertension (7.5%),Eosinophilic myocarditis (<7%),Premature ventricular beats (5%; dose related),Angina (1-3%),Dyspnea (1-3%),Fever (1-3%),Headache (1-3%),Nausea (1-3%),Palpation (1-3%)
Frequency Not Defined
Cardiac dysrhythmia,Exacerbation of coronary arteriosclerosis,Hypokalemia,Injection-site reactions,Syncope,10- to 20-mm Hg increase in systolic blood pressure and increase in heart rate of 5 to 15 beats/min
Potentially Fatal: Cardiac arrhythmias, allergy (rare), MI and hypotension.
Pregnancy Category Note
Pregnancy category: B
Lactation: Unknown whether drug is excreted into breast milk; avoid use
Interaction
Increased cardiac output when used with nitroprusside. Increased vasopressor effect of dobutamine when used with bretylium, guanethidine, oxytocic drugs or TCAs.