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Doxiderm
Incepta Pharmaceuticals Ltd.
Generic: Doxepin 5% Topical
Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Doxiderm.
CONSULT YOUR DOCTOR
Doxiderm may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Doxiderm is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
The baby should be monitored carefully for excessive sleepiness, and adequate weight gain.
UNSAFE
Doxiderm may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
SAFE IF PRESCRIBED
Doxiderm is safe to use in patients with kidney disease. No dose adjustment of Doxiderm is recommended.
However, talk to your doctor if you have any underlying kidney disease.
CAUTION
Doxiderm should be used with caution in patients with liver disease. Dose adjustment of Doxiderm may be needed. Please consult your doctor.
Medicine Overview of Doxiderm 50mg/1g Cream
Introduction
Doxiderm is a tricyclic antidepressant. It is used in the treatment of insomnia (difficulty in sleeping). It is also used in patients intolerant of or unresponsive to alternative (other) treatment options for depression and anxiety disorders. Doxiderm works by increasing the levels of chemical messengers in the brain that stabilizes and enhances the mood. It is usually advised to take it before bedtime because it can make you feel drowsy. It can be taken with or without food, but you should take it at a fixed time each day for better efficacy. The dose and duration will be decided by...
... Show moreUses of Doxiderm
- Insomnia
- Depression
- Anxiety
Side effects of Doxiderm
Common
- Constipation
- Difficulty in urination
- Dryness in mouth
- Increased heart rate
- Orthostatic hypotension (sudden lowering of blood pressure on standing)
- Weight gain
How to use Doxiderm
Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Doxiderm may be taken with or without food, but it is better to take it at a fixed time.
How Doxiderm works
Doxiderm is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.
What if you forget to take Doxiderm?
If you miss a dose of Doxiderm, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Doxiderm helps in the treatment of insomnia, depression and anxiety.
- Inform your doctor if you notice behavioral changes, mood changes and suicidal thoughts while taking this medicine.
- Inform your doctor if you notice a loss of consciousness, agitation, reduced breathing rate, convulsions, muscle rigidity, and mouth dryness.
- You may be asked for regular blood tests to monitor the blood cell count or level of sodium and sugar in the blood.
- Do not drive or do anything that requires concentration until you know how the medicine affects you.
- Do not stop taking the medication suddenly without talking to your doctor.
Brief Description
Indication
Pruritus, Chronic idiopathic urticaria (hives), Atopic dermatitis, lichen simplex chronicus
Adult Dose
Adult: apply thinly 3-4 times daily; usual max. 3 g per application; usual total max. 12 g daily; coverage should be less than 10% of body surface area.
Use in Elderly Patients:
Dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range.
Child Dose
Child over 12 years: apply thinly 3-4 times daily; usual max. 3 g per application; usual total max. 12 g daily; coverage should be less than 10% of body surface area.
The use of Doxepin cream in pediatric patients is not recommended.
Contraindication
Patients with untreated narrow angle glaucoma or a tendency to urinary retention because doxepin HCl has an anticholinergic effect
Individuals who have shown previous sensitivity to any of its components
Mode of Action
Potent histamine H1- & H2-receptor antagonist activity.
Precaution
Cautions should be exercised if there is susceptibility to angle-closure glaucoma, urinary retention, severe liver impairment, mania and also in pregnancy and breast-feeding. Drowsiness may affect performance of skilled tasks (e.g. driving) so patient should be careful.
Lactation: may pass into breast milk; do not nurse
Side Effect
>10%
Burning/stinging (23%),Drowsiness (20%; esp if applied to >10% BSA)
1-10%
Dizziness,Dry mouth,Eczema exacerbated,Edema,Fatigue,Mental changes,Pruritus,Taste perversion
Pregnancy Category Note
Pregnancy Category: B
Lactation: May pass into breast milk; do not nurse
Interaction
Methylphenidate may increase plasma doxepin levels.
Potentially Fatal: Potentiates hypertensive action of sympathomimetics. Increased anticholinergic effects with MAOIs. Additive CNS effects with anticholinergics, CNS depressants and alcohol.
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