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Cetrolix
Eskayef Pharmaceuticals Ltd.
Generic: Cetrorelix
Safety Advices
বাংলা
English
CAUTION
Caution is advised when consuming alcohol with Cetrolix. Please consult your doctor.
UNSAFE
Cetrolix is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
UNSAFE
Cetrolix is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
SAFE
Cetrolix does not usually affect your ability to drive.
CAUTION
Cetrolix should be used with caution in patients with kidney disease. Dose adjustment of Cetrolix may be needed. Please consult your doctor.
However, the use of Cetrolix is not recommended in patients with severe kidney disease.
CAUTION
Cetrolix should be used with caution in patients with liver disease. Dose adjustment of Cetrolix may be needed. Please consult your doctor.
Medicine Overview of Cetrolix 0.25mg Injection
Introduction
Cetrolix is an anti-gonadotropin-releasing hormone medicine. It is used in the treatment of infertility in females. It restricts eggs to release directly and prevents premature ovulation. Cetrolix is injecting directly into the skin under the supervision of a doctor. Do not self administer the injection. Your doctor or nurse may help you to know the best way to inject the medicine at home. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as...
... Show moreUses of Cetrolix
- Female infertility
Side effects of Cetrolix
Common
- Nausea
- Ovarian hyperstimulation syndrome
- Injection site reactions (pain, swelling, redness)
- Itching
- Irritation
- Vomiting
- Lower abdominal pain
How to use Cetrolix
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Cetrolix works
In females undergoing treatment for infertility, sometimes premature ovulation can lead to the release of eggs which are not ready for fertilisation. Cetrolix blocks the action of a natural hormone and prevents premature release of the eggs from the ovary.
What if you forget to take Cetrolix?
If you miss a dose of Cetrolix, please consult your doctor.
Quick Tips
- Cetrolix helps prevent premature ovulation in women undergoing assisted reproduction treatments such as IVF.
- It is given as an injection under the skin (subcutaneously), preferably of the upper leg.
- Inform your doctor immediately if you get very dizzy, faint, vomit, or have diarrhea while using this medicine. These could be symptoms of ovarian hyperstimulation syndrome (OHSS).
- Do not use this medicine if you are already pregnant or breastfeeding.
Brief Description
Indication
Assisted reproductive technologies, In-vitro fertilization
Adult Dose
Subcutaneous
Assisted reproductive technologies
Adult: As acetate: equiv to 0.25 mg cetrorelix either in the morning beginning on the day 5 or 6 of ovarian stimulation or in the evening beginning on day 5, and continued until ovulation induction.
Renal Dose
Severe renal impairment: Contraindicated
Contraindication
Hypersensitivity. Moderate to severe renal or hepatic impairment. Women with severe allergic conditions. Pregnancy and lactation;
Mode of Action
Cetrorelix, a synthetic decapeptide analog of naturally occurring gonadorelin, is a gonadorelin antagonist. It competitively blocks gonadorelin receptors on the anterior piyuitary gonadotroph and the subsequent transduction pathway, inducing a rapid, reversible suppression of gonadotrophin secretion.
Precaution
Women with active allergic conditions or a history of allergies; childn; elderly >65 yrs
Lactation: Excretion in milk unknown/contraindicated
Side Effect
1-10%
Ovarian hyperstimulation syndrome (4%),Nausea (1%),Hepatic enzyme elevation (1-2%),Headache (1%)
<1%
Erythema at injection site,Itching,Pruritus,Swelling,Redness,Hypotension,Rash,Cough
Pregnancy Category Note
Pregnancy Category: X
Lactation: Excretion in milk unknown/contraindicated
Interaction
In vitro investigations have shown that interactions are unlikely with medications that are metabolised by cytochrome P-450 or glucuronised or conjugated in some other way. However, the possibility of interactions with commonly used medicinal products can not entirely be excluded.
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