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Exforge 5/80

Tablet-(5mg+80mg)
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Nevian Lifescience PLC
14 Tablets (1 Strip)
৳ 659.84
৳ 707
7% OFF

Medicine Overview of Exforge 5/80 5mg+80mg Tablet

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Introduction

Exforge 5/80 contains two medicines, both of which help to control high blood pressure. It lowers the blood pressure by relaxing the blood vessels and making it easier for your heart to pump blood around your body. This will reduce your risk of having a heart attack or a stroke. Exforge 5/80 may be taken on an empty stomach or along with food. However, it is better to take it regularly at a fixed time each day, as prescribed by your doctor. The dose will depend on your condition and how you respond to the medicine. It's important to keep taking this medicine even if you feel well. By lowering your blood pressure, it is reducing your risk of heart attack or stroke so do not stop taking it unless your doctor tells you to. You can help this medicine work better by making a few changes to your lifestyle such as keeping active, stopping smoking, and eating a low salt and low fat diet. The most common side effects of this medicine include swelling in your ankles or feet (oedema), headache, sleepiness, dizziness, tiredness, taste change, and upset stomach. Since it may cause sleepiness and dizziness, do not drive or do anything requiring concentration until you know how it affects you. Talk to your doctor if any of the side effects bother you or will not go away. Before taking this medicine, let your doctor know if you have any kidney or liver problems or severe dehydration. Pregnant or breastfeeding women should also consult their doctor before taking it. While using this medicine, your blood pressure will need to be checked often and your kidney function may also need to be tested.

Uses of Exforge 5/80

  • Hypertension (high blood pressure)

Side effects of Exforge 5/80

Common
  • Headache
  • Dizziness
  • Ankle swelling
  • Tiredness
  • Palpitations
  • Increased potassium level in blood
  • Sleepiness
  • Taste change
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Upset stomach

How to use Exforge 5/80

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Exforge 5/80 may be taken with or without food, but it is better to take it at a fixed time.

How Exforge 5/80 works

Exforge 5/80 is a combination of two medicines: Amlodipine and Valsartan, which lowers blood pressure effectively. Amlodipine is a calcium channel blocker (CCB) and Valsartan is an angiotensin receptor blocker (ARB). They work by relaxing the blood vessels and making the heart more efficient at pumping blood throughout the body.

Quick Tips

  • Valembic 80 AM Tablet is a combination of two medicines that provides better blood pressure control than either medicine alone.
  • Valembic 80 AM Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • It may cause you to feel lightheaded or weak especially when you stand up. Rise slowly if you have been sitting or lying down.
  • Avoid consuming alcohol as it may enhance the blood pressure lowering effect of this medicine.
  • It can cause ankle or foot swelling. Raise your legs while you are sitting down and talk to your doctor if it does not go away.
  • Do not take Valembic 80 AM Tablet if you are pregnant, planning to conceive or breastfeeding.

Brief Description

Indication

Hypertension Initiate with 5 mg/160 mg PO qDay OR Substitute for individually titrated components May increase dose after at least 2 weeks, not to exceed 10 mg/day amlodipine and 320 mg/day valsartan May be adminsitered concomitantly with other antihypertensive agents Hepatic impairment Not recommended for initial therapy; amlodipine 2.5 mg is not an available strength with available dosage forms for this drug combination Amlodipine: Exposure is increased with hepatic insufficiency, consider decreasing dose Valsartan: Exposure increased with mild-to-moderate hepatic insufficiency does not require dosage adjustment; unknown for severe hepatic impairment Elderly: Since both components of the combination are equally well tolerated when used at similar doses in elderly or younger patients, normal dosage regimens are recommended.

Administration

Amlodipine : Plasma concentrations may be elevated w/ CYP3A4 inhibitors (e.g. azole antifungals, ritonavir). Concomitant therapy w/ simvastatin may increase risk of myopathy including rhabdomyolysis. May increase ciclosporin plasma levels and conivaptan. Valsartan : May antagonise hypotensive effects and increase the risk of renal impairment w/ NSAIDs. Increased risk of hyperkalaemia w/ K-sparing diuretics, K supplements or K-containing salt substitutes. Potentially Fatal: Increased risk of hypotension, hyperkalemia and changes in renal function (including acute renal failure) when used w/ aliskiren in patients w/ diabetes and renal impairment (GFR <60 mL/min).

Adult Dose

Impaired liver or renal function, CHF, sick-sinus syndrome, severe ventricular dysfunction, hypertrophic cardiomyopathy, severe aortic stenosis. Caution when used in patients with idiopathic hypertrophic subaortic stenosis. Elderly, children. During the second and third trimesters of pregnancy, these drugs have been associated with fetal injury that includes hypotension, neonatal skull hypoplasia, anuria, reversible or irreversible renal failure, and death. Discontinue as soon as possible when pregnancy is detected; affects renin-angiotensin system causing oligohydramnios, which may result in fetal injury and/or death Lactation: discontinue drug or do not nurse

Child Dose

Pregnancy Category: C (1st trimester); D (2nd & 3rd trimesters).

Renal Dose

Amlodipine relaxes peripheral and coronary vascular smooth muscle. It produces coronary vasodilation by inhibiting the entry of Ca ions into the slow channels or select voltage-sensitive channels of the vascular smooth muscle and myocardium during depolarisation. It also increases myocardial oxygen delivery in patients w/ vasospastic angina. Valsartan, an angiotensin II type 1 (AT1) receptor antagonist, produces its BP lowering effects by inhibiting angiotensin II-induced vasoconstriction, aldosterone release and renal reabsorption of Na.

Mode of Action

May be taken with or without food.

Precaution

Hypertension

Side Effect

Renal impairment Mild or moderate (CrCl >30 mL/min): Dose adjustment not necessary Severe (CrCl <30 mL/min): Not studied

Pregnancy Category Note

>10% Headache,Increased BUN (6-17%) 1-10% Peripheral edema (5-8%),Anxiety (3%),Nasopharyngitis (4%),Increased potassium (3%),Upper respiratory infection (3%),Dizziness (2%),Somnolence (3%),Diarrhea (3%),Nausea (3%),Abdominal pain (3%),Cough (2%) <1% Orthostatic hypotension,Syncope,Visual disturbance,Tinnitus,Exanthema Potentially Fatal: Hypotension, bradycardia, conductive system delay and CCF.

Interaction

Known hypersensitivity to dihydropyridines.

Buy Exforge 5/80 from Arogga

In Bangladesh, you can get the original Exforge 5/80. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Exforge 5/80 in Bangladesh?

The latest price of Exforge 5/80 in Bangladesh is 659.84. You can buy Exforge 5/80 at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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UNSAFE
It is unsafe to consume alcohol with Exforge 5/80.
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CONSULT YOUR DOCTOR
Exforge 5/80 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
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SAFE IF PRESCRIBED
Exforge 5/80 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
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UNSAFE
Exforge 5/80 may cause side effects which could affect your ability to drive. Exforge 5/80 may cause side effects such as dizziness, headaches, nausea or tiredness, all of which could affect your ability to concentrate and drive.
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CAUTION
Exforge 5/80 should be used with caution in patients with severe kidney disease. Dose adjustment of Exforge 5/80 may be needed. Please consult your doctor. Regular blood pressure monitoring is recommended. No dose adjustment is needed in patients with mild to moderate kidney disease.
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CAUTION
Exforge 5/80 should be used with caution in patients with liver disease. Dose adjustment of Exforge 5/80 may be needed. Please consult your doctor.
Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.