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Spotex

cream-(0.1%)
brand logo
Opsonin Pharma Limited

Generic: Tretinoin

1 x 50gm tube
৳ 450
৳ 500
10% OFF

Medicine Overview of Spotex 0.1% cream

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Introduction

Spotex is a form of vitamin A that is used to treat acne which appears as spots or pimples on your face, chest or back. It also helps to smooth rough facial skin and to reduce fine wrinkles on the skin. Spotex reduces excessive oil production of the skin. Ideally, a pinpoint application at nighttime is recommended for the duration prescribed by your doctor. The amount you need and for how long you need to take it will depend on what you are being treated for. You should normally wash and dry the affected area before applying a thin layer of this medicine. Follow your doctor's instructions. You should not apply it to damaged or broken skin and avoid contact with your mouth, eyes and nose. It may take several weeks for your symptoms to improve but keep using it regularly to get the most benefit. Consult your doctor again if you do not notice any improvement after a few weeks. Using more medicine or applying it more often than prescribed will not make it work any faster and may increase the side effects. The most common side effects include irritation, dryness and redness of the skin. They are usually mild and improve as your body gets used to the medicine. Drink plenty of water and use moisturizer as it may lead to dryness of the mouth, lips and eyes. Let your doctor know if these side effects bother you or do not go away. Serious side effects with this medicine are rare. This medicine may make you more sensitive to sunlight so you should limit exposure to the sun if possible. It may make your skin more fragile. It is advised, not to have any waxing (hair removal), or laser treatments during treatment. Pregnant women or women who are planning to get pregnant should not use this medicine as it can lead to birth defects.

Uses of Spotex

  • Acne

Side effects of Spotex

Common
  • Erythema (skin redness)
  • Skin irritation
  • Dry skin
  • Dry lips
  • Pale red skin
  • Increased sensitivity to light

How to use Spotex

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

How Spotex works

Spotex is a form of vitamin A. When applied on skin, it reduces oil production in the skin, replenishes acne-prone skin and helps keep your pores open.

What if you forget to take Spotex?

If you miss a dose of Spotex, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick Tips

  • You have been prescribed Spotex for the treatment of acne.
  • Clean the affected area with water and a non-medicated soap. Let it dry for 20-30 minutes before applying Spotex.
  • It may increase the severity of the spots or pimples in the first few weeks of use. Continue using it as prescribed by your doctor.
  • It may cause a stinging sensation or a feeling of warmth when you first start using it. Inform your doctor if this persists.
  • Avoid exposure to sunlight while using Spotex as it increases the sensitivity of your skin. Use protective measures such as sunscreen or protective clothing.
  • Avoid face waxing and laser treatment while using this medicine as it makes your skin more fragile.
  • Avoid taking tetracycline (e.g. doxycycline) as it may reduce the Spotex activity.
  • Do not use Spotex if you are pregnant.
  • Inform your doctor if excessive skin dryness or skin sensitivity take place.

Brief Description

Indication

Acute promyelocytic leukaemia

Administration

Should be taken with food.

Adult Dose

Oral Acute promyelocytic leukaemia Adult: Remission induction: 45 mg/m2 daily in 2 divided doses. Treatment is continued until 30 days after complete remission or up to 90 days, whichever occurs first. Hepatic impairment: Reduce dose to 25 mg/m2 daily.

Child Dose

Oral Acute promyelocytic leukaemia Child: Remission induction: 1-16 yr 45 mg/m2 daily in 2 divided doses. Treatment is continued until 30 days after complete remission or up to 90 days, whichever occurs first. Hepatic impairment: Reduce dose to 25 mg/m2 daily.

Renal Dose

Renal impairment: Reduce dose to 25 mg/m2 daily.

Contraindication

Hypersensitivity to retinoids. Application to eczematous, sunburnt or abraded skin. Pregnancy, lactation.

Mode of Action

Tretinoin is a trans-retinoic acid form of vitimin A. It stimulates mitosis and turnover of follicular epithelial cells and reduce their cohesiveness. This facilitates extrusion of existing comedones and prevents formation of new comedone. It also exhibits thinning effect on the stratum corneum. In acute promyelocytic leukaemia, it induces cellular differentiation and decreases proliferations.

Precaution

Children, hepatic or renal impairment. Reduce dose if intractable headache occurs. Discontinue temporarily if LFT exceed 5 times upper limit of normal. Monitor closely for leukocytosis or respiratory compromise. Monitor haematologic profile, coagulation parameters, LFT, serum triglyceride and cholesterol concentrations regularly. Lactation: Unknown if excreted in breast milk; do not breast-feed, because of potential for serious adverse reactions in infant

Side Effect

>10% Headache (86%),Fever (83%),Bone pain (77%),Dry mucous membranes (77%),Malaise (67%),URI (63%),Shivering (60%),Dyspnea (60%),Hemorrhage (60%),Elevated liver function tests (50-60%),Hyperlipidemia (60%).Infections (58%),Nausea and vomiting (57%),Rash (54%),Peripheral edema (52%),Leukocytosis (40%),Pain (37%),Abdominal pain (31%),DIC (26%),Respiratory insufficiency (26%),Mucositis (26%),GI disorder (26%),Retinoic acid-APL syndrome (25%),Ear ache (23%),Diarrhea (23%),Pleural effusion (20%),Dizziness (20%),Pruritus (20%),Sweating (20%),Anxiety (17%),Paresthesia (17%),Constipation (17%),Vision changes (17%),Dyspepsia (14%),Depression(14%),Insomnia (14%),Alopecia (14%),Skin changes (14%),Confusion (11%),Abdominal distention (11%),Renal insufficiency (11%) 1-10% (selected) Cardiac failure,Pseudotumor cerebri,Ulcer Potentially Fatal: Retinoic acid syndrome, cardiac arrthythmia, disseminated intravascular coagulation, blood dyscrasias, cardiac arrest, cerebral haemorrhage.

Interaction

Enhances percutaneous absorption of minoxidil. Increased risk of fatal thrombotic complications with antifibrinolytic. Increased tretinoin concentrations with azole antifungals. Enhances peeling action of sulphur, resorcinol, benzoyl peroxide, salicylic acid. Increased photosensitivity with photosensitising medications eg, thiazides, tetracyclines, fluoroquinolones, phenothiazines and sulfonamides. Potentially Fatal: Increased risk of intracranial pressure with tetracyclines.

Buy Spotex from Arogga

In Bangladesh, you can get the original Spotex. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Spotex in Bangladesh?

The latest price of Spotex in Bangladesh is 450৳. You can buy Spotex at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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No interaction found/established
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CONSULT YOUR DOCTOR
Spotex may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
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SAFE IF PRESCRIBED
Spotex is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
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No interaction found/established
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No interaction found/established
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No interaction found/established

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.