ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন

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Caripran 1.5

Name: Caripran 1.5 1.5mg capsule
Brand: Incepta Pharmaceuticals Ltd.
SKU: ARG-MED-P-78147
Price: 123.5 BDT
Availability: InStock
Rating: 4.9 (1 reviews)

capsule - (1.5mg)

Incepta Pharmaceuticals Ltd.

Generic: Cariprazine

Medicine Overview of Caripran 1.5 1.5mg capsule

বাংলা

English

Indication

Schizophrenia, Indicated for acute treatment of manic or mixed episodes associated with, bipolar disorder

Administration

Take orally with or without food

Adult Dose

Adults Schizophrenia Starting dose: 1.5 mg PO qDay Dose may be increased to 3 mg/day on Day 2 Depending upon clinical response and tolerability, further dose adjustments can be made in 1.5 to 3-mg increments Dosage range: 1.5-6 mg PO qDay Bipolar Disorder Indicated for acute treatment of manic or mixed episodes associated with bipolar I disorder Starting dose: 1.5 mg PO qDay Dose should be increased to 3 mg/day on Day 2 Depending on clinical response and tolerability, further dose adjustments can be made in 1.5 to 3-mg increments Dosage range: 3-6 mg PO qDay Hepatic impairment Mild-to-moderate (Child-Pugh...

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Renal Dose

Renal impairment Mild-to-moderate (CrCl ?30 mL/min): No dosage adjustment required Severe (CrCl <30 mL/min): Not recommended; safety and efficacy has not been established

Contraindication

History of hypersensitivity to cariprazine

Mode of Action

Precise mechanism by which cariprazine works for schizophrenia or bipolar disorder is unknown Efficacy could be mediated through a combination of partial agonist activity at central dopamine (D2) and serotonin 5-HT1A receptors Forms 2 major metabolites, desmethyl cariprazine (DCAR) and didesmethyl cariprazine (DDCAR), that have in vitro receptor binding profiles similar to the parent drug

Precaution

Antipsychotic drugs increase the all-cause risk of death in elderly patients with dementia-related psychosis; a higher incidence of stroke and TIA, including fatal stroke, was also observed (see Black Box Warnings) Hypersensitivity reactions have ranged from rash, pruritus, urticaria, and events suggestive of angioedema (eg, swollen, tongue, lip swelling, face edema, pharyngeal edema, facial swelling) Neuroleptic malignant syndrome reported; monitor for hyperpyrexia, muscle rigidity, delirium, and autonomic instability; other signs include increased CPK, myoglobinuria (rhabdomyolysis), and acute renal failure; if NMS is suspected, immediately discontinue treatment Tardive dyskinesia, a potentially irreversible, involuntary, dyskinetic movement syndrome, may develop in patients treated...

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Side Effect

>10% (Schizophrenia) Extrapyramidal symptoms, all (24-33%) Parkinsonism (13-18%) Headache (9-18%) Akathisia (9-14%) Insomnia (11-13%) >10% (Bipolar Disorder) Extrapyramidal symptoms, all (41-45%) Parkinsonism (21-26%) Akathisia (20-21%) Headache (13-14%) Nausea (11-13%) Constipation (6-11%) 1-10% (Schizophrenia) Constipation (6-10%) Somnolence (5-10%) Nausea (5-8%) Abdominal pain (3-7%) Restlessness (4-6%) Anxiety (3-6%) Toothache (3-6%) Hypertension (2-6%) Dyspepsia (4-5%) Vomiting (4-5%) Dizziness (3-5%) Agitation (3-5%) Diarrhea (1-5%) Pain in extremity (2-4%) Cough (1-4%) Tachycardia (2-3%) Increased weight (2-3%) Decreased appetite (1-3%) Dry mouth (1-3%) Fatigue (1-3%) Increased CPK (1-3%) Musculoskeletal stiffness (1-3%) Back pain (1-3%) Dystonia (2%) Tachycardia (1-2%) Arthralgia (1-2%) Increased LFTs (1-2%) Nasopharyngitis (1-2%) Urinary...

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Pregnancy Category Note

Pregnancy Neonates exposed to antipsychotic drugs during third trimester of pregnancy are at risk for extrapyramidal symptoms or withdrawal symptoms after delivery; these complications vary in severity, with some being self-limited and others requiring ICU support and prolonged hospitalization Lactation Unknown if distributed in human breast milk Present in rat milk Consider the developmental and health benefits of breastfeeding along with the mother’s clinical need for the drug, and any potential adverse effects on the breastfed infant from the drug or from the underlying maternal condition

Interaction

Coadministration with a strong CYP3A4 inhibitor increases the exposures of cariprazine and its major active metabolite, didesmethylcariprazine (DDCAR), compared to use of cariprazine alone

ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন

0 People recently viewed this

Caripran 1.5

capsule - (1.5mg)

Incepta Pharmaceuticals Ltd.

Generic: Cariprazine

Additional Offers

Cashback

৳50

For purchasing above ৳5000+

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৳40

For purchasing above ৳4000+

Cashback

৳30

For purchasing above ৳3000+

Cashback

৳20

For purchasing above ৳2000+

Cashback

৳10

For purchasing above ৳1000+

Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.