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Melphalan 50 IV Infusion

injection-(50mg/vial)
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Renata Limited

Generic: Melphalan

1 x 50mg Vial
৳ 7740
৳ 8600
10% OFF

Medicine Overview of Melphalan 50 IV Infusion 50mg/vial injection

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Introduction

Melphalan 50 IV Infusion is used to treat cancer of ovaries and a type of cancer of bone marrow called multiple myeloma. It may be also used to treat other conditions, as determined by the doctor. Melphalan 50 IV Infusion should be taken on an empty stomach, but try to take it at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes skin more sensitive towards sunlight, wear protective clothing or use sunscreen. The most common side effects of this medicine include nausea, vomiting, and anemia (low number of red blood cells). This medicine may reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. Inform your doctor if you observe signs of infections such as fever, chills, body ache or if you have unusual bruising or bleeding and bleeding gums or blood in your urine or stool. Before taking it, tell your doctor if you have bleeding, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Melphalan 50 IV Infusion

  • Ovarian cancer
  • Multiple myeloma

Side effects of Melphalan 50 IV Infusion

Common
  • Nausea
  • Vomiting
  • Stomatitis (Inflammation of the mouth)
  • Anemia (low number of red blood cells)
  • Hair loss
  • Low blood platelets
  • Diarrhea
  • Decreased white blood cell count

How to use Melphalan 50 IV Infusion

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Melphalan 50 IV Infusion is to be taken empty stomach.

How Melphalan 50 IV Infusion works

Melphalan 50 IV Infusion is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

What if you forget to take Melphalan 50 IV Infusion?

If you miss a dose of Melphalan 50 IV Infusion, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick Tips

  • Melphalan 50 IV Infusion should be taken as per dose and duration suggested by the doctor.

Brief Description

Indication

Breast cancer, Ovarian cancer, Multiple myeloma, Neuroblastoma, Soft tissue sarcoma, Malignant melanoma, Retinoblastoma, Polycythaemia vera

Administration

Should be taken on an empty stomach. Take on an empty stomach 1 hr before or 2 hr after meals.

Adult Dose

Adult Multiple Myeloma Palliative treatment Indicated for the palliative treatment of patients with MM Oral 6 mg PO qDay for 2-3 weeks, OR 10 mg PO qDay for 7-10 days, OR 0.15 mg/kg/day PO for 7 days, THEN After adequate recovery from toxicity (monitor WBCs and platelets) give 1-3 mg or 0.05 mg/kg PO qDay Intravenous If unable to take oral, may administer IV 16 mg/m² IV as a single infusion over 15-20 minutes q2wk for 4 doses, THEN After adequate recovery from toxicity (monitor WBCs and platelets) administer q4wk Conditioning treatment Indicated for use as a high-dose conditioning treatment prior to hematopoietic progenitor (stem) cell transplantation 100 mg/m²/day IV administered over 30 min for 2 consecutive days (Day -3 and Day -2) prior to autologous stem cell transplantation (ASCT, Day 0) Patients weighing >130% of their ideal body weight, body surface area should be calculated based on adjusted ideal body weight Oral Ovarian Cancer 0.2 mg/kg/day PO for 5 days; repeat q4-5Weeks Breast cancer Adult: 150 mcg/kg daily or 6 mg/m2 daily for 5 days, repeated every 6 wk. Elderly Multiple Myeloma Induction 6 mg PO qDay for 2-3 weeks, OR 10 mg PO qDay for 7-10 days, OR 0.15 mg/kg/day PO for 7 days, OR 16 mg/m² IV q2Weeks for 4 doses Maintenance Wait until WBC and platelet counts rise 1-3 mg PO qDay, OR 0.05 mg/kg/day PO, OR 16 mg/m² IV q4Weeks Ovarian Cancer 0.2 mg/kg/day PO for 5 days; repeat q4-5Weeks

Child Dose

Safety and efficacy not established

Renal Dose

Renal impairment (BUN >30 mg/dL): Consider dosage reduction of up to 50%

Contraindication

Hypersensitivity. Severe bone marrow suppression. Pregnancy.

Mode of Action

Melphalan, a mechlorethamine derivative, is an alkylating antineoplastic agent. It forms carbonium ions, resulting in DNA and RNA synthesis inhibition. It cross-links DNA strands and acts on both resting and rapidly dividing tumour cells.

Precaution

Renal impairment. Lactation. Prior bone marrow suppression, prior chemotherapy or irradiation. May mask signs of infection e.g. fever and increased WBC. Elderly. Lactation: not known if excreted in breast milk

Side Effect

>10% Myelosuppression (30%) Frequency Not Defined Diarrhoea, stomatitis, vomiting; haemolytic anaemia, vasculitis, pulmonary fibrosis, hepatic disorders, suppression of ovarian function in premenopausal women, temporary or permanent sterility in male patients. Allergic reactions. Potentially Fatal: Bone marrow suppression. Secondary malignancy, cardiac arrest. Anaphylaxis.

Interaction

Potentially Fatal: Fatal haemorrhagic enterocolitis with concurrent nalidixic acid in children. Potentiates risk of renal damage with ciclosporin.

Buy Melphalan 50 IV Infusion from Arogga

In Bangladesh, you can get the original Melphalan 50 IV Infusion. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Melphalan 50 IV Infusion in Bangladesh?

The latest price of Melphalan 50 IV Infusion in Bangladesh is 7740৳. You can buy Melphalan 50 IV Infusion at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Melphalan 50 IV Infusion. Please consult your doctor.
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CONSULT YOUR DOCTOR
Melphalan 50 IV Infusion is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
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UNSAFE
Melphalan 50 IV Infusion is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
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CONSULT YOUR DOCTOR
It is not known whether Melphalan 50 IV Infusion alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
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CAUTION
Melphalan 50 IV Infusion should be used with caution in patients with kidney disease. Dose adjustment of Melphalan 50 IV Infusion may be needed. Please consult your doctor.
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CONSULT YOUR DOCTOR
There is limited information available on the use of Melphalan 50 IV Infusion in patients with liver disease. Please consult your doctor.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.