Keratoconjunctivitis, recurrent epithelial keratitis, due to herpes simplex viruses
Adult Dose
Ophthalmic
Primary keratoconjunctivitis and recurrent epithelial keratitis due to herpes simplex viruses
Adult: As 1% soln: Instill 1 drop into affected eye 2 hrly. Max: 9 drops daily, until complete re-epithelialisation. Reduce to 1 drop 4 hrly (Min 5 drops daily) for 7 days. Treatment should not exceed 21 days.
Child Dose
Ophthalmic
Primary keratoconjunctivitis and recurrent epithelial keratitis due to herpes simplex viruses
Child: >6 yr: Instill 1 drop into affected eye 2 hrly. Max: 9 drops daily, until complete re-epithelialisation. Reduce to 1 drop 4 hrly (Min 5 drops daily) for 7 days. Treatment should not exceed 21 days.
Contraindication
Hypersensitivity.
Mode of Action
Trifluridine interferes with the synthesis of viral DNA following phosphorylation. It is active against HSV types 1 and 2 and vaccinia virus.
Precaution
Pregnancy; child 21 days to be avoided due to risk of ocular toxicity.
Side Effect
Transient burning or stinging upon instillation, irritation, hyperemia, palpebral oedema, dry eye, superficial punctate keratopathy, epithelial keratopathy, hypersensitivity reaction and increased intraocular pressure.
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.