Neufil 120 IV/SC Injection - Image 1
Express delivery icon 12-24 HOURS

ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন

Register
186 people viewed this
info-icon
info-icon
info-icon

Neufil 120 IV/SC Injection

Injection-(120mcg/0.2ml)
brand logo
Healthcare Pharmaceuticals Ltd.

Generic: Filgrastim

1 Injection
৳ 1377.50
৳ 1450
5% OFF

Medicine Overview of Neufil 120 IV/SC Injection 120mcg/0.2ml Injection

Switch language Iconবাংলা

Introduction

Neufil 120 IV/SC Injection is used to prevent infections after chemotherapy. It is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections. Neufil 120 IV/SC Injection is given as an injection by a qualified medical professional. You should continue to take as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. You might be asked for regular tests done to check the number of blood cells in your blood and your bone density level while you are taking this medicine. The most common side effects of this medicine include bone pain, weakness, headache, and rash. Other than this, pain or redness at the site of injection is common. But, inform your doctor if you notice a lump, swelling, or bruising that does not go away. It might not prevent you from all kinds of infection, hence inform your doctor if you notice fever, chills, rash, sore throat and swelling around face or neck. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Neufil 120 IV/SC Injection

  • Infections after chemotherapy

Side effects of Neufil 120 IV/SC Injection

Common
  • Bone pain
  • Weakness
  • Headache
  • Rash
  • Nausea
  • Increased lactate dehydrogenase level in blood
  • Vomiting
  • Increased uric acid level in blood
  • Oropharyngeal pain
  • Hair loss
  • Fatigue
  • Diarrhea
  • Constipation
  • Decreased appetite
  • Cough
  • Breathing problems

How to use Neufil 120 IV/SC Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Neufil 120 IV/SC Injection works

Neufil 120 IV/SC Injection is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections. .

What if you forget to take Neufil 120 IV/SC Injection?

If you miss a dose of Neufil 120 IV/SC Injection, please consult your doctor.

Quick Tips

  • Neufil 120 IV/SC Injection reduces the risk of infection in people treated with chemotherapy.
  • It is usually given as a daily injection into the tissue just under the skin or into the vein.
  • You will normally receive your first dose at least 24 hours after your chemotherapy or bone marrow transplant.
  • Store it in the refrigerator, protect it from light, and don't shake it.
  • For a more comfortable injection, leave the syringe at room temperature for 30 minutes before using it.
  • Pain or redness in the area of injection is common. Let your doctor know if you notice a lump, swelling, or bruising that doesn't go away.
  • Use caution while driving or doing anything that requires concentration as Neufil 120 IV/SC Injection may cause dizziness.
  • Your doctor may get regular tests done to monitor the number of blood cells in your blood, and your bone density level while you are receiving treatment with this medicine.
  • Stop taking Neufil 120 IV/SC Injection and inform your doctor if you have a fever, shortness of breath, fast rate of breathing or trouble breathing.

Brief Description

Indication

Myelosuppressive chemotherapy, Acute Myeloid Leukemia, receiving induction or consolidation chemotherapy, Peripheral blood progenitor cell collection and therapy, Severe Neutropenia, Bone marrow transplantation, HIV infection.

Administration

IV Preparation Vials may be diluted in D5W to >15 mcg/mL for infusion 5-15 mcg/mL dilution: Protect from adsorption to plastic materials by the addition of human albumin to a final concentration of 2 mg/mL Do not dilute with saline at any time, because the product may precipitate IV Administration Short IV infusion over 15-30 min, OR Continuous IV infusion SC Administration Administer undiluted by SC in the outer area of upper arms, abdomen, thighs, or upper outer areas of the buttock

Adult Dose

Parenteral Chemotherapy-induced neutropenia Adult: 5 mcg/kg daily as a single daily SC inj, as a continuous IV or SC infusion, or as a daily IV infusion over 15-30 minutes, starting not <24 hr after the last dose of antineoplastic. Continue treatment until neutrophil count has stabilised within the normal range which may take up to 14 days or more. Bone marrow transplantation Adult: 10 mcg/kg daily by IV infusion over 30 min or 4 hr or continuous IV or SC infusion over 24 hr. Adjust according to response. Subcutaneous Mobilisation of peripheral blood progenitor cells for autologous peripheral blood stem cell transplantation Adult: 10 mcg/kg daily, as a single inj or by continuous infusion, for 4-7 days until the last leucapheresis procedure. If it is given after myelosuppressive chemotherapy: 5 mcg/kg daily by inj; given from the 1st day after chemotherapy completion until expected neutrophil nadir is passed and neutrophil count has returned to normal range, so that leucapheresis can be performed. Congenital neutropenia Adult: 12 mcg/kg daily in single or divided doses. Adjust according to response. In patients with cyclic or idiopathic neutropenia: 5 mcg/kg daily in single or divided doses. Adjust according to response. HIV infection and persistent neutropenia Adult: Initially, 1 mcg/kg daily. Dose may be increased to 4 mcg/kg daily until normal neutrophil count is achieved. Maintenance: 300 mcg daily. Max: 4 mcg/kg daily.

Contraindication

Hypersensitivity to E. coli derived proteins, Filgrastim or any component of the product. Myeloid malignancies. Not to be used within 24 hr of cytotoxic chemotherapy admin due to the sensitivity of rapidly dividing myeloid cells. Severe congenital neutropaenia (Kostman's syndrome) with abnormal cytogenetics.

Mode of Action

Filgrastim is a granulocyte-colony stimulating factor which binds to cell surface receptors on haemetopoietic cells thus stimulating the development of granulocytes to increase their migration and cytotoxicity.

Precaution

Filgrastim should not be administered within 24 hours before and after chemotherapy. Premalignant or malignant myeloid condition; sickle-cell disease; osteoporotic bone disease; withdraw treatment if there are signs of pulmonary infiltrates. Fluid retention or heart failure. Monitor CBC and platelet count during therapy. Monitor bone density in patients with osteoporosis (long-term treatment). Regular morphological and cytogenic bone-marrow examinations in severe congenital neutropenia. Pregnancy and lactation. Lactation: excretion in milk unknown; use with caution

Side Effect

>10% Nausea (57%),Vomiting (57%),Bone pain (22%-33%),Alopecia (18%),Diarrhea (14%),Fever (12%),Fatigue (11%) 1-10% Headache,Anorexia,Chest pain,Cough,Dyspnea,Constipation,Stomatitis,Sore throat,Rash Frequency Not Defined Elevated uric acid,Elevated lactate dehydrogenase,Elevated alkaline phosphatase Potentially Fatal: Pulmonary infiltrates leading to resp failure or acute resp distress syndrome.

Pregnancy Category Note

Pregnancy Available data from published studies, including several observational studies of pregnancy outcomes in women exposed to filgrastim products and those who were unexposed, have not established an association with use during pregnancy and major birth defects, miscarriage, or adverse maternal or fetal outcomes Reports in scientific literature have described transplacental passage of drug in pregnant women when administered less than or equal to 30 hours prior to preterm delivery (less than or equal to 30 weeks' gestation) In animal reproduction studies, effects of filgrastim on prenatal development have been studied in rats and rabbits; no malformations were observed in either species; no maternal or fetal effects were observed in pregnant rats at doses up to 58 times the human doses; drug has been shown to have adverse effects in pregnant rabbits at doses 2 -10 times higher than the human doses Lactation There is published literature documenting transfer of filgrastim into human milk; there are a few case reports describing use of filgrastim in breastfeeding mothers with no adverse effects noted in the infants; there are no data on effects of filgrastim on milk production; other filgrastim products are secreted poorly into breast milk, and filgrastim products are not absorbed orally by neonates; developmental and health benefits of breastfeeding should be considered along with mother’s clinical need for therapy and any potential adverse effects on the breastfed child from the drug or from underlying maternal condition

Interaction

Myelosuppressive antineoplastic agents. Drugs which may potentiate the release of neutrophils e.g. lithium.

Buy Neufil 120 IV/SC Injection from Arogga

In Bangladesh, you can get the original Neufil 120 IV/SC Injection. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Neufil 120 IV/SC Injection in Bangladesh?

The latest price of Neufil 120 IV/SC Injection in Bangladesh is 1377.5. You can buy Neufil 120 IV/SC Injection at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

Rocket Icon
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Neufil 120 IV/SC Injection. Please consult your doctor.
Rocket Icon
CONSULT YOUR DOCTOR
Neufil 120 IV/SC Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Rocket Icon
SAFE IF PRESCRIBED
Neufil 120 IV/SC Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Rocket Icon
UNSAFE
Neufil 120 IV/SC Injection may cause side effects which could affect your ability to drive. Neufil 120 IV/SC Injection may cause fatigue. This may affect your driving ability.
Rocket Icon
SAFE IF PRESCRIBED
Neufil 120 IV/SC Injection is safe to use in patients with kidney disease. No dose adjustment of Neufil 120 IV/SC Injection is recommended.
Rocket Icon
SAFE IF PRESCRIBED
Neufil 120 IV/SC Injection is safe to use in patients with liver disease. No dose adjustment of Neufil 120 IV/SC Injection is recommended.
Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.